Pedro Torres-Ayuso
ptorresayuso.bsky.social
Pedro Torres-Ayuso
@ptorresayuso.bsky.social
Assistant Professor @templemedschool @FoxChaseCancer. #Kinase #SignalingNetworks; #PrecisionMedicine; #LungCancer & #HeadandNeck #CancerResearch.
Reposted by Pedro Torres-Ayuso
Super pleased to announce our latest suggesting the cell of origin for #SCLC is most likely the basal cell @nature.com, not the accepted neuroendocrine cell. Implications for the earliest events in cancer, & providing new models of tuft-like cancer.
rdcu.be/eGUtj
Basal cell of origin resolves neuroendocrine–tuft lineage plasticity in cancer
Nature - Basal cells, rather than neuroendocrine cells, have been identified as the probable origin of small cell lung cancer and other neuroendocrine–tuft cancers, explaining...
rdcu.be
September 17, 2025 at 3:21 PM
Reposted by Pedro Torres-Ayuso
Excited about my first PhD Poster Presentation at Dawn Marks Research Day 2025! Shared research on mitochondrial metabolism in squamous cancers. Big thanks to everyone for their insights and to my mentor @ptorresayuso.bsky.social. Looking forward to more learning and networking! #KatzTempleMed
August 31, 2025 at 2:49 AM
Reposted by Pedro Torres-Ayuso
I am so lucky to count with the amazing #oneandonly @rolanddunbrack.bsky.social as my colleague and thrilled to count him as my dear friend!!!
#congratulations!!!
September 6, 2025 at 3:30 PM
Reposted by Pedro Torres-Ayuso
Online now: Online Now: FAK inhibition combined with the RAF-MEK clamp avutometinib overcomes resistance to targeted and immune therapies in BRAF V600E melanoma
FAK inhibition combined with the RAF-MEK clamp avutometinib overcomes resistance to targeted and immune therapies in BRAF V600E melanoma
By transcriptomic analysis, Lubrano et al. demonstrate that FAK-regulated pathways are enriched in BRAFi+MEKi-resistant melanoma lesions. In BRAF V600E melanomas, MAPK inhibition decreases RhoE (RND3) expression, activating the RhoA-FAK-AKT pathway and…
dlvr.it
February 28, 2025 at 12:53 PM
Reposted by Pedro Torres-Ayuso
Hi greater Philly area folks, here's the link to the local site for this action. It will be 3/7 at 11am at City Hall. An important opportunity to make it clear that science in the US as we know it is in danger! Science is for everyone and benefits everyone. standupforscience2025.org/philadelphia...
February 24, 2025 at 1:14 AM
Reposted by Pedro Torres-Ayuso
Welcome to the Bluesky account for Stand Up for Science 2025!

Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!

#scienceforall #sciencenotsilence
February 12, 2025 at 5:04 PM
Reposted by Pedro Torres-Ayuso
The Stand Up For Science website has been updated. Find your local protest site! March 7! Get out there!

standupforscience2025.org
STAND UP FOR SCIENCE
March 7, 2025. Washington DC and Nationwide. Because Science is for everyone.
standupforscience2025.org
February 22, 2025 at 12:34 AM
Reposted by Pedro Torres-Ayuso
President Trump's NIH cuts will damage our health, our research, and our global leadership.

Thanks to my 149 House Democratic colleagues who joined @amo.house.gov, @degette.house.gov, @replindasanchez.bsky.social, and me in making the case to rescind harmful NIH cuts.
February 21, 2025 at 4:09 PM
Reposted by Pedro Torres-Ayuso
🧬 Happy International Day of Women and Girls in Science! 🧬

Today we celebrate metastasis research leaders:

🔬 Dr. Alana Welm @alanawelm.bsky.social, MRS President.

🔬 Dr. Neta Erez @netaerez.bsky.social, incoming President.

Inspiring the future! 💪✨ #WomenInScience #IDWGS #MetastasisResearch
February 12, 2025 at 12:22 AM
Reposted by Pedro Torres-Ayuso
Kudos to the @theaacr.bsky.social for making it easy to reach out to your representatives. Nice to see courage and action. nam02.safelinks.protection.outlook.com?url=https%3A...
AACR Legislative Action Center
Directly contact your elected officials about the importance of cancer research, the need for continued funding and the latest lifesaving breakthroughs. In the United States, you can do so by sending ...
nam02.safelinks.protection.outlook.com
February 18, 2025 at 10:27 PM
Reposted by Pedro Torres-Ayuso
The AACR is deeply concerned that the Administration’s recent actions are threatening NIH and its mission to accelerate progress for patients with cancer and other diseases that afflict millions of Americans. Read our statement: https://buff.ly/4gRXNB8
February 18, 2025 at 6:09 PM
Reposted by Pedro Torres-Ayuso
AACR urges Congress to reaffirm its long history of steadfast and bipartisan support for medical research by ensuring that NIH has all of the resources needed to advance its lifesaving mission to prevent, diagnose, and treat cancer and other diseases: AACR.org/NIH
February 18, 2025 at 6:10 PM
Reposted by Pedro Torres-Ayuso
🧪Researchers at @irbbarcelona.org and the @upf.edu unravel peroxiredoxinylation, a type of post-translational modification.

✍️ Gerhard Seisenbacher, @laia-de-nadal.bsky.social, Francesc Posas, et al.

📰 Cell Reports

➡️ bit.ly/4k53Hlq

📌DOI: 10.1016/j.celrep.2024.115224

#IRBScience #ChemBio
February 18, 2025 at 9:59 AM
Reposted by Pedro Torres-Ayuso
This week we had International Day of Women and Girls in Science 👩‍🔬 🥼 🔬

There are many women working to provided the resources at PDBe, AlphaFoldDB, EMDB and EMPIAR. Lets met a few of them!

#IDWGS #WomeninSTEM #WomenInScience #WhatAScientistLooksLike
February 14, 2025 at 5:30 PM
Reposted by Pedro Torres-Ayuso
My lab is looking for an enthusiastic postdoc interested in studying lysosomal signaling dynamics in cardiac health and disease. Those especially interested in development & use of targeted biosensors and dynamic super-resolution imaging are encouraged to apply. www.nature.com/naturecareer...
Postdoctoral Fellow - Philadelphia, Pennsylvania (US) job with Temple University School of Medicine | 12836829
Postdoctoral fellow within the Aging + Cardiovascular Discovery Center at Temple University
nam10.safelinks.protection.outlook.com
February 7, 2025 at 7:50 PM
Reposted by Pedro Torres-Ayuso
Breaking news: 22 states are suing to block NIH’s cutting of indirect costs.

See our updated story on the Friday night news and its aftermath. scim.ag/4hTJQ6v
NIH slashes overhead payments for research, sparking outrage and lawsuit
Move to cut indirect cost rate to 15% could cost universities billions of dollars
scim.ag
February 10, 2025 at 6:43 PM
Reposted by Pedro Torres-Ayuso
My #Yale colleague Harlan Krumholz explains why the cuts to indirect costs are a disaster for biomedical research in the United States. Want to do something about it? I'll list those who have to hear from us below. Share, recruit friends and family to help. 1/ www.statnews.com/2025/02/08/n....
The NIH’s drastic cut to indirect cost rates is a critical threat to U.S. research infrastructure
The drastic reduction in indirect costs is not a path to innovation or cost savings — it’s a threat to U.S.’s position as global leader in medical research.
www.statnews.com
February 9, 2025 at 10:29 AM
Reposted by Pedro Torres-Ayuso
1. Today the NIH director issued a new directive slashing overhead rates to 15%.

I want to provide some context on what that means and why it matters.

grants.nih.gov/grants/guide...
NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD
grants.nih.gov
February 8, 2025 at 12:18 AM
Reposted by Pedro Torres-Ayuso
I wrote this just two weeks ago - could not have imagined how broadly #science and #researchers in the US have been impacted since then



Science is a #global community 🌍 🌎 🌏

We're all very concerned for our friends, colleagues, and young researchers in the US right now



#solidarityforscience 🧪
Seeing a huge increase in applications to our lab from scientists in the US 🧪 in the last few months

It feels like the coming years are going to have a far-reaching impact on global science..
February 1, 2025 at 1:10 PM
Reposted by Pedro Torres-Ayuso
Here's what I've heard so far from inside the National Cancer Institute as well as other NIH institutes.
Trump's Assault on NIH Will Kill People With Cancer
Splinter is your home for news and opinions that challenge power in our political and economic system that's becoming more unhinged each and every day.
www.splinter.com
January 25, 2025 at 6:27 PM
Reposted by Pedro Torres-Ayuso
'Most Americans probably don’t know this, but so much of what we take for granted when we seek care in the US—the medicines, the diagnostics, the procedures—have come out of NIH research.'
@gregggonsalves.bsky.social
www.thenation.com/article/soci...
Trump Is Trying to Destroy Public Health in America
The administration has forced crucial scientific activity to grind to a halt. It’s an act of national suicide.
www.thenation.com
January 25, 2025 at 1:56 AM