Magnus Kjærgaard
@proteinmagnus.bsky.social
Protein biophysicist working on intrinsically disordered proteins in neuroscience and biotech. Assoc. prof at @MolBiolAU and @PromemoAU. (He/Him)
Would you like to hear about our work developing a screening pipeline for de novo designed binders us the microfluidic sizing?
Then tune in on Thursday for a virtual seminar. Sign-up below:
fidabio.webinargeek.com/how-to-scree...
Then tune in on Thursday for a virtual seminar. Sign-up below:
fidabio.webinargeek.com/how-to-scree...
September 29, 2025 at 1:49 PM
Would you like to hear about our work developing a screening pipeline for de novo designed binders us the microfluidic sizing?
Then tune in on Thursday for a virtual seminar. Sign-up below:
fidabio.webinargeek.com/how-to-scree...
Then tune in on Thursday for a virtual seminar. Sign-up below:
fidabio.webinargeek.com/how-to-scree...
We find that it works excellently with “boiling lysis” – exploiting the high thermostability of binder designs to remove endogenous proteins – and then simply dilution the supernatant with buffer before measurement.
June 19, 2025 at 6:45 AM
We find that it works excellently with “boiling lysis” – exploiting the high thermostability of binder designs to remove endogenous proteins – and then simply dilution the supernatant with buffer before measurement.
FIDA measure radius of hydration based on diffusion in a microfluidic capillary.
This allows us to pick out successful binders based on the increase in R_H – a one-point measurement for initial screening and titration for affinity determination.
This allows us to pick out successful binders based on the increase in R_H – a one-point measurement for initial screening and titration for affinity determination.
June 19, 2025 at 6:45 AM
FIDA measure radius of hydration based on diffusion in a microfluidic capillary.
This allows us to pick out successful binders based on the increase in R_H – a one-point measurement for initial screening and titration for affinity determination.
This allows us to pick out successful binders based on the increase in R_H – a one-point measurement for initial screening and titration for affinity determination.
The most wholesome Fox News show: 5 fox cubs playing in our garden.
May 17, 2025 at 1:54 PM
The most wholesome Fox News show: 5 fox cubs playing in our garden.
Baby fox in the garden!
May 15, 2025 at 6:35 PM
Baby fox in the garden!
Trigger warning: FOMO
How often do you go to a conference where you are excited about EVERY SINGLE TALK! Well, I guess it helps if you get to make the program. 😀
"Biomolecular condensates: From fundamental principles to applications in health and biotech" kicking off at 9 AM!
How often do you go to a conference where you are excited about EVERY SINGLE TALK! Well, I guess it helps if you get to make the program. 😀
"Biomolecular condensates: From fundamental principles to applications in health and biotech" kicking off at 9 AM!
May 13, 2025 at 5:31 AM
Trigger warning: FOMO
How often do you go to a conference where you are excited about EVERY SINGLE TALK! Well, I guess it helps if you get to make the program. 😀
"Biomolecular condensates: From fundamental principles to applications in health and biotech" kicking off at 9 AM!
How often do you go to a conference where you are excited about EVERY SINGLE TALK! Well, I guess it helps if you get to make the program. 😀
"Biomolecular condensates: From fundamental principles to applications in health and biotech" kicking off at 9 AM!
Probably the best conference venue in Denmark?
Tomorrow, we kick-off our condensate meeting in the Carlsberg Academy ⬇️.
Thank you to the Novo Nordisk Foundation for the grant to host our dream meeting, and to the Carlsberg Foundation for hosting us at this beautiful site.
Tomorrow, we kick-off our condensate meeting in the Carlsberg Academy ⬇️.
Thank you to the Novo Nordisk Foundation for the grant to host our dream meeting, and to the Carlsberg Foundation for hosting us at this beautiful site.
May 12, 2025 at 6:03 PM
Probably the best conference venue in Denmark?
Tomorrow, we kick-off our condensate meeting in the Carlsberg Academy ⬇️.
Thank you to the Novo Nordisk Foundation for the grant to host our dream meeting, and to the Carlsberg Foundation for hosting us at this beautiful site.
Tomorrow, we kick-off our condensate meeting in the Carlsberg Academy ⬇️.
Thank you to the Novo Nordisk Foundation for the grant to host our dream meeting, and to the Carlsberg Foundation for hosting us at this beautiful site.
Impressive outreach setup at Aarhus Uni’s “Ole Rømer Observatory”. A shame that it is always clouded here though 😅☁️
January 17, 2025 at 9:10 PM
Impressive outreach setup at Aarhus Uni’s “Ole Rømer Observatory”. A shame that it is always clouded here though 😅☁️
The Danish Villum Foundation seems to be concerned about the cost of writing unsuccesful grants and are experimenting with their call to solve this.
Examples:
* Pre-application lottery for who gets to apply
* Institutions are only allowed to apply in alternating years
Examples:
* Pre-application lottery for who gets to apply
* Institutions are only allowed to apply in alternating years
January 16, 2025 at 1:26 PM
The Danish Villum Foundation seems to be concerned about the cost of writing unsuccesful grants and are experimenting with their call to solve this.
Examples:
* Pre-application lottery for who gets to apply
* Institutions are only allowed to apply in alternating years
Examples:
* Pre-application lottery for who gets to apply
* Institutions are only allowed to apply in alternating years
The methods sections in published papers are usually not very detailed when it comes to the analysis:
December 5, 2024 at 11:01 AM
The methods sections in published papers are usually not very detailed when it comes to the analysis:
What is the most rigorous way to determine the cloud point of a phase separating system from scattering data (as the attached)?
We had a long discussion about this at group meeting yesterday without reaching a clear conclusion?
We had a long discussion about this at group meeting yesterday without reaching a clear conclusion?
December 5, 2024 at 10:59 AM
What is the most rigorous way to determine the cloud point of a phase separating system from scattering data (as the attached)?
We had a long discussion about this at group meeting yesterday without reaching a clear conclusion?
We had a long discussion about this at group meeting yesterday without reaching a clear conclusion?
Actually, one of the very first proteins I ever worked (uPAR) on had a domain structure very similar to neurotoxins 😀:
November 29, 2024 at 10:27 AM
Actually, one of the very first proteins I ever worked (uPAR) on had a domain structure very similar to neurotoxins 😀:
Do you need a starting pack of researcher working on intrinsically disordered proteins?
Well, you might head over to @idpseminars.bsky.social and hit followers.
Tw***** was important for the birth of IDPseminars and for spreading the word. It would be cool to re-kindle that community here.
Well, you might head over to @idpseminars.bsky.social and hit followers.
Tw***** was important for the birth of IDPseminars and for spreading the word. It would be cool to re-kindle that community here.
November 25, 2024 at 11:44 AM
Do you need a starting pack of researcher working on intrinsically disordered proteins?
Well, you might head over to @idpseminars.bsky.social and hit followers.
Tw***** was important for the birth of IDPseminars and for spreading the word. It would be cool to re-kindle that community here.
Well, you might head over to @idpseminars.bsky.social and hit followers.
Tw***** was important for the birth of IDPseminars and for spreading the word. It would be cool to re-kindle that community here.
Do you know our next PhD students?
We have two openings starting this summer, one for engineering of biomolecular condensates, and one for de novo design of protein binders (and their applications).
Details ⬇️
We have two openings starting this summer, one for engineering of biomolecular condensates, and one for de novo design of protein binders (and their applications).
Details ⬇️
January 8, 2024 at 2:16 PM
Do you know our next PhD students?
We have two openings starting this summer, one for engineering of biomolecular condensates, and one for de novo design of protein binders (and their applications).
Details ⬇️
We have two openings starting this summer, one for engineering of biomolecular condensates, and one for de novo design of protein binders (and their applications).
Details ⬇️
On Thursday, we welcome Ayala Lampel (Tel Aviv Uni) and Karen Duff (UK Dementia Research Institute) at IDPseminars.
Topics will be minimalistic peptide condensates and abnormal tau in neurodegenerative disorders.
New attendees can sign up at: idpseminars.com
Topics will be minimalistic peptide condensates and abnormal tau in neurodegenerative disorders.
New attendees can sign up at: idpseminars.com
December 12, 2023 at 7:56 AM
On Thursday, we welcome Ayala Lampel (Tel Aviv Uni) and Karen Duff (UK Dementia Research Institute) at IDPseminars.
Topics will be minimalistic peptide condensates and abnormal tau in neurodegenerative disorders.
New attendees can sign up at: idpseminars.com
Topics will be minimalistic peptide condensates and abnormal tau in neurodegenerative disorders.
New attendees can sign up at: idpseminars.com
The joys of navigating the European train system amid overlapping German and Belgian train strikes include visiting unexpected destinations 😌
December 7, 2023 at 4:00 PM
The joys of navigating the European train system amid overlapping German and Belgian train strikes include visiting unexpected destinations 😌
Peer review - pro-tip! 😎
December 6, 2023 at 2:09 PM
Peer review - pro-tip! 😎
New toy in the lab! Thanks to the Carlsberg Foundation (and beer drinkers around the world) our core facility has a brand new ITC (Malvern PEAQ-ITC). Looking forward to all the data it will generate!
November 15, 2023 at 8:01 AM
New toy in the lab! Thanks to the Carlsberg Foundation (and beer drinkers around the world) our core facility has a brand new ITC (Malvern PEAQ-ITC). Looking forward to all the data it will generate!
Are interactions between intrinsically disordered proteins too naughty for Microsoft?
My entry in the "PhD thesis title as DALL-E 3 prompt" was declared "unsafe content".
My entry in the "PhD thesis title as DALL-E 3 prompt" was declared "unsafe content".
November 2, 2023 at 8:59 AM
Are interactions between intrinsically disordered proteins too naughty for Microsoft?
My entry in the "PhD thesis title as DALL-E 3 prompt" was declared "unsafe content".
My entry in the "PhD thesis title as DALL-E 3 prompt" was declared "unsafe content".
New lab equipment/art installation designed by the technicians on our floor. 😂
October 23, 2023 at 11:12 AM
New lab equipment/art installation designed by the technicians on our floor. 😂
IDPseminars happening tomorrow!
CEST 19:00, UK 6PM, Eastern 1PM, Pacific 10 AM, New Zealand Friday 6 AM (sorry Davide, but thank you for your dedication!)
Link should have been sent out by email to those already registered. New attendees sign-up at: www.idpseminars.com
CEST 19:00, UK 6PM, Eastern 1PM, Pacific 10 AM, New Zealand Friday 6 AM (sorry Davide, but thank you for your dedication!)
Link should have been sent out by email to those already registered. New attendees sign-up at: www.idpseminars.com
October 18, 2023 at 9:05 AM
IDPseminars happening tomorrow!
CEST 19:00, UK 6PM, Eastern 1PM, Pacific 10 AM, New Zealand Friday 6 AM (sorry Davide, but thank you for your dedication!)
Link should have been sent out by email to those already registered. New attendees sign-up at: www.idpseminars.com
CEST 19:00, UK 6PM, Eastern 1PM, Pacific 10 AM, New Zealand Friday 6 AM (sorry Davide, but thank you for your dedication!)
Link should have been sent out by email to those already registered. New attendees sign-up at: www.idpseminars.com
The AI apocalypse just moved closer! Now they have learned to use knives! 😳
October 15, 2023 at 12:30 PM
The AI apocalypse just moved closer! Now they have learned to use knives! 😳
Exciting big box waiting outside our biophysics core facility!
October 9, 2023 at 6:19 AM
Exciting big box waiting outside our biophysics core facility!
Time to put the tortoises in the fridge. See you in six months!
October 8, 2023 at 4:12 PM
Time to put the tortoises in the fridge. See you in six months!
New program out for IDPseminars!
New attendees sign up here: idpseminars.com
We have relied heavily on Twitter for our PR until now, so its slow but painful death spiral leaves us in a bit of a pickle. Please help us rebuild our following over here by re-tweeting.
New attendees sign up here: idpseminars.com
We have relied heavily on Twitter for our PR until now, so its slow but painful death spiral leaves us in a bit of a pickle. Please help us rebuild our following over here by re-tweeting.
October 6, 2023 at 1:00 PM
New program out for IDPseminars!
New attendees sign up here: idpseminars.com
We have relied heavily on Twitter for our PR until now, so its slow but painful death spiral leaves us in a bit of a pickle. Please help us rebuild our following over here by re-tweeting.
New attendees sign up here: idpseminars.com
We have relied heavily on Twitter for our PR until now, so its slow but painful death spiral leaves us in a bit of a pickle. Please help us rebuild our following over here by re-tweeting.