Preslava
@preslavatdrv.bsky.social
PhD student at KCL interested in neurodevelopmental disorders, E/I balance and gene therapy
Reposted by Preslava
SCN2A loss is strongly linked to neurodevelopmental delays and, at times, seizure. In an amazing collaboration with @nadavahituv.bsky.social, led by Serena Tamura, Andrew Nelson, and Perry Spratt, we leveraged CRISPR activator approaches to rescue this loss.
rdcu.be/eGU0W
rdcu.be/eGU0W
CRISPR activation for SCN2A-related neurodevelopmental disorders
Nature - Using SCN2A haploinsufficiency as a proof-of-concept, upregulation of the existing functional gene copy through CRISPR activation was able to rescue neurological-associated phenotypes in...
rdcu.be
September 17, 2025 at 6:27 PM
SCN2A loss is strongly linked to neurodevelopmental delays and, at times, seizure. In an amazing collaboration with @nadavahituv.bsky.social, led by Serena Tamura, Andrew Nelson, and Perry Spratt, we leveraged CRISPR activator approaches to rescue this loss.
rdcu.be/eGU0W
rdcu.be/eGU0W
Reposted by Preslava
Planning to record LTP or LTD in acute brain slices with whole-cell patch clamp? Give my latest article on Scientifica's NeuroWire a look! www.scientifica.uk.com/learning-zon... #plasticity #patchclamp #electrophysiology #ephys 🔬🪄⚡️
Electrophysiology protocols for LTP and LTD: Recording synaptic…
Learn how to record LTP and LTD using whole-cell patch clamp. Step-by-step guide to measuring synaptic plasticity in individual neurons
www.scientifica.uk.com
September 1, 2025 at 4:25 AM
Planning to record LTP or LTD in acute brain slices with whole-cell patch clamp? Give my latest article on Scientifica's NeuroWire a look! www.scientifica.uk.com/learning-zon... #plasticity #patchclamp #electrophysiology #ephys 🔬🪄⚡️