Prateek Yadav
@prateekjaiyadav.bsky.social
Biologist in the making|
BS-MS @iiserpune| MSCA @Cell2_Cell
PhD student @siegel-lab.bsky.social in @bmc-lmu.bsky.social |
Part of @crc1064.bsky.social
Trying to visualize genome architecture during antigenic variation
BS-MS @iiserpune| MSCA @Cell2_Cell
PhD student @siegel-lab.bsky.social in @bmc-lmu.bsky.social |
Part of @crc1064.bsky.social
Trying to visualize genome architecture during antigenic variation
Reposted by Prateek Yadav
Hi there! Our group at LMU Munich is hiring a postdoc to work on Toxoplasma and Plasmodium.
Start: from Oct 1, 2025 | Location: Munich, Germany
1-year contract with extension possible
Apply by Aug 31: bit.ly/LMUpostdoc
Contact: elena.jimenez@lmu.de
Start: from Oct 1, 2025 | Location: Munich, Germany
1-year contract with extension possible
Apply by Aug 31: bit.ly/LMUpostdoc
Contact: elena.jimenez@lmu.de
bit.ly
August 8, 2025 at 6:40 AM
Hi there! Our group at LMU Munich is hiring a postdoc to work on Toxoplasma and Plasmodium.
Start: from Oct 1, 2025 | Location: Munich, Germany
1-year contract with extension possible
Apply by Aug 31: bit.ly/LMUpostdoc
Contact: elena.jimenez@lmu.de
Start: from Oct 1, 2025 | Location: Munich, Germany
1-year contract with extension possible
Apply by Aug 31: bit.ly/LMUpostdoc
Contact: elena.jimenez@lmu.de
Reposted by Prateek Yadav
We’re very excited about the potential of IACS for advancing infectious disease research and believe this review from the Goda lab and its collaborators in @natrevbioeng.nature.com highlights its many powerful applications. Check out the full paper here: www.nature.com/articles/s44...
July 18, 2025 at 9:21 AM
We’re very excited about the potential of IACS for advancing infectious disease research and believe this review from the Goda lab and its collaborators in @natrevbioeng.nature.com highlights its many powerful applications. Check out the full paper here: www.nature.com/articles/s44...
Reposted by Prateek Yadav
June was a productive month: brought two things into this world, both of which were great collaborative efforts and about nine months in the making. Check out where we map P. falciparum genome architecture at high resolution with Micro-C here:
www.nature.com/articles/s41...
www.nature.com/articles/s41...
June 30, 2025 at 3:22 PM
June was a productive month: brought two things into this world, both of which were great collaborative efforts and about nine months in the making. Check out where we map P. falciparum genome architecture at high resolution with Micro-C here:
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Prateek Yadav
We’re excited to share our review: "Next-generation genetic screens in kinetoplastids", now published in NAR!
It covers a range of perturbation methods—from RNAi to prime editing—as well as emerging assay technologies like scRNA-seq and image-activated cell sorting.
academic.oup.com/nar/article/...
It covers a range of perturbation methods—from RNAi to prime editing—as well as emerging assay technologies like scRNA-seq and image-activated cell sorting.
academic.oup.com/nar/article/...
Next generation genetic screens in kinetoplastids
Abstract. The genomes of all organisms encode diverse functional elements, including thousands of genes and essential noncoding regions for gene regulation
academic.oup.com
June 23, 2025 at 12:57 PM
We’re excited to share our review: "Next-generation genetic screens in kinetoplastids", now published in NAR!
It covers a range of perturbation methods—from RNAi to prime editing—as well as emerging assay technologies like scRNA-seq and image-activated cell sorting.
academic.oup.com/nar/article/...
It covers a range of perturbation methods—from RNAi to prime editing—as well as emerging assay technologies like scRNA-seq and image-activated cell sorting.
academic.oup.com/nar/article/...
Reposted by Prateek Yadav
Next generation genetic screens in kinetoplastids pubmed.ncbi.nlm.nih.gov/40530689/
June 19, 2025 at 4:34 PM
Next generation genetic screens in kinetoplastids pubmed.ncbi.nlm.nih.gov/40530689/
Reposted by Prateek Yadav
🚨 Preprint Alert 🚨
We performed genetic crosses between phenotypically different Cryptosporidium strains and identified genomic loci responsible for their differences!
#Cryptosporidium #Genomics #Parasitology #InfectiousDiseases #Preprint #BioRxiv
www.biorxiv.org/content/10.1...
We performed genetic crosses between phenotypically different Cryptosporidium strains and identified genomic loci responsible for their differences!
#Cryptosporidium #Genomics #Parasitology #InfectiousDiseases #Preprint #BioRxiv
www.biorxiv.org/content/10.1...
Genetic crosses reveal genomic loci responsible for virulence in Cryptosporidium parvum infection
The relationship between parasite genotype and pathogenesis is largely unknown for Cryptosporidium, a leading cause of diarrheal disease in children. An array of parasites with similar genomes produce...
www.biorxiv.org
May 22, 2025 at 3:52 PM
🚨 Preprint Alert 🚨
We performed genetic crosses between phenotypically different Cryptosporidium strains and identified genomic loci responsible for their differences!
#Cryptosporidium #Genomics #Parasitology #InfectiousDiseases #Preprint #BioRxiv
www.biorxiv.org/content/10.1...
We performed genetic crosses between phenotypically different Cryptosporidium strains and identified genomic loci responsible for their differences!
#Cryptosporidium #Genomics #Parasitology #InfectiousDiseases #Preprint #BioRxiv
www.biorxiv.org/content/10.1...
Reposted by Prateek Yadav
Just a reminder, if you haven’t already signed up for the workshops to please do so – the link to do so is in your ticket confirmation. Do get in touch with us by email if you encounter any issues with registrations.
📌For more info and to register: www.munich-interact.de
📌For more info and to register: www.munich-interact.de
Interact Munich 2025
PhD conference, interact 2025, organised in Munich, Germany. Great opportunity for PhD candidates to network with fellow early career researchers and learn about their future career opportunities.
www.munich-interact.de
March 28, 2025 at 12:32 PM
Just a reminder, if you haven’t already signed up for the workshops to please do so – the link to do so is in your ticket confirmation. Do get in touch with us by email if you encounter any issues with registrations.
📌For more info and to register: www.munich-interact.de
📌For more info and to register: www.munich-interact.de
Reposted by Prateek Yadav
⏳The work week may be almost over but the countdown to (and the registration for 👀) <interact> is in its final stages! We're less than a week away from the big event, and we couldn't be more excited!✨🎉
March 28, 2025 at 12:32 PM
⏳The work week may be almost over but the countdown to (and the registration for 👀) <interact> is in its final stages! We're less than a week away from the big event, and we couldn't be more excited!✨🎉
Reposted by Prateek Yadav
Delighted to have been part of this great work driven by @marketanovotna.bsky.social in the Horn lab, showing the power of precision editing to study the direct role of histone modifications on gene expression regulation! Check it out!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Precision-edited histone tails disrupt polycistronic gene expression controls in trypanosomes
Transcription of protein coding genes in trypanosomatids is atypical and almost exclusively polycistronic. In Trypanosoma brucei, approximately 150 polycistrons, and 8000 genes, are constitutively tra...
www.biorxiv.org
March 24, 2025 at 8:35 AM
Delighted to have been part of this great work driven by @marketanovotna.bsky.social in the Horn lab, showing the power of precision editing to study the direct role of histone modifications on gene expression regulation! Check it out!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Prateek Yadav
📢Workshop registrations also open this week on Thursday the 20th of March 2025. Information and link for workshop registrations will be also on our website and spots will be given out on a first-come-first-serve basis (and of course, only to people with a valid ticket 😉).
March 19, 2025 at 10:09 AM
📢Workshop registrations also open this week on Thursday the 20th of March 2025. Information and link for workshop registrations will be also on our website and spots will be given out on a first-come-first-serve basis (and of course, only to people with a valid ticket 😉).
Reposted by Prateek Yadav
⏳We've started the countdown to <interact>! Get excited🎉
📢The deadline for ticket sales is next Friday on the 28th of March 2025. There are limited numbers of tickets left - be sure to register early on our website!
📢The deadline for ticket sales is next Friday on the 28th of March 2025. There are limited numbers of tickets left - be sure to register early on our website!
March 19, 2025 at 10:09 AM
⏳We've started the countdown to <interact>! Get excited🎉
📢The deadline for ticket sales is next Friday on the 28th of March 2025. There are limited numbers of tickets left - be sure to register early on our website!
📢The deadline for ticket sales is next Friday on the 28th of March 2025. There are limited numbers of tickets left - be sure to register early on our website!
Reposted by Prateek Yadav
How Pathogens Outsmart the Immune System!
💡 A new @nature.com study by Maria Colomé-Tatché and @siegel-lab.bsky.social shows how #pathogens control changes in their #cell #surface to evade the #immune #system. 🧪
➡️ www.med.lmu.de/bmc/en/news/...
@lmumuenchen.bsky.social @www.helmholtz-munich.de
💡 A new @nature.com study by Maria Colomé-Tatché and @siegel-lab.bsky.social shows how #pathogens control changes in their #cell #surface to evade the #immune #system. 🧪
➡️ www.med.lmu.de/bmc/en/news/...
@lmumuenchen.bsky.social @www.helmholtz-munich.de
Antigenic variation: decoding the mechanism controlling antigen activation in trypanosomes
A new study by Maria Colomé-Tatché and Nicolai Siegel shows how pathogens control changes in their cell surface to evade the immune system.
www.med.lmu.de
March 18, 2025 at 9:37 AM
How Pathogens Outsmart the Immune System!
💡 A new @nature.com study by Maria Colomé-Tatché and @siegel-lab.bsky.social shows how #pathogens control changes in their #cell #surface to evade the #immune #system. 🧪
➡️ www.med.lmu.de/bmc/en/news/...
@lmumuenchen.bsky.social @www.helmholtz-munich.de
💡 A new @nature.com study by Maria Colomé-Tatché and @siegel-lab.bsky.social shows how #pathogens control changes in their #cell #surface to evade the #immune #system. 🧪
➡️ www.med.lmu.de/bmc/en/news/...
@lmumuenchen.bsky.social @www.helmholtz-munich.de
Reposted by Prateek Yadav
Antigenic Variation: How Parasites Outsmart the Immune System 🦠
A new study by #HelmholtzMunich & LMU reveals how Trypanosoma brucei controls antigen switching to evade the immune system.
👉 t1p.de/n37tm
@lmumuenchen.bsky.social
#AntigenicVariation #Trypanosomes #Genomics #InfectiousDiseases
A new study by #HelmholtzMunich & LMU reveals how Trypanosoma brucei controls antigen switching to evade the immune system.
👉 t1p.de/n37tm
@lmumuenchen.bsky.social
#AntigenicVariation #Trypanosomes #Genomics #InfectiousDiseases
March 13, 2025 at 10:09 AM
Antigenic Variation: How Parasites Outsmart the Immune System 🦠
A new study by #HelmholtzMunich & LMU reveals how Trypanosoma brucei controls antigen switching to evade the immune system.
👉 t1p.de/n37tm
@lmumuenchen.bsky.social
#AntigenicVariation #Trypanosomes #Genomics #InfectiousDiseases
A new study by #HelmholtzMunich & LMU reveals how Trypanosoma brucei controls antigen switching to evade the immune system.
👉 t1p.de/n37tm
@lmumuenchen.bsky.social
#AntigenicVariation #Trypanosomes #Genomics #InfectiousDiseases
Reposted by Prateek Yadav
Happy to share our latest pre-print!
We solved the cryoEM structures of human DNA repair factor MRN bound to DNA and to TRF2. Main work of Yilan, Filiz @filizkuybu.bsky.social and Hengjun. Great collab within the @sfb1361.bsky.social and @genecenter-lmu.bsky.social 🧬🔨
www.biorxiv.org/content/10.1...
We solved the cryoEM structures of human DNA repair factor MRN bound to DNA and to TRF2. Main work of Yilan, Filiz @filizkuybu.bsky.social and Hengjun. Great collab within the @sfb1361.bsky.social and @genecenter-lmu.bsky.social 🧬🔨
www.biorxiv.org/content/10.1...
Structural basis for DNA double-strand break sensing by human MRE11-RAD50-NBS1 and its TRF2 complex
The MRE11-RAD50-NBS1 (MRN) complex is a central, multifunctional factor in the detection, signaling and nucleolytic processing of DNA double-strand breaks (DSBs). To clarify how human MRN binds generi...
www.biorxiv.org
March 17, 2025 at 9:43 AM
Happy to share our latest pre-print!
We solved the cryoEM structures of human DNA repair factor MRN bound to DNA and to TRF2. Main work of Yilan, Filiz @filizkuybu.bsky.social and Hengjun. Great collab within the @sfb1361.bsky.social and @genecenter-lmu.bsky.social 🧬🔨
www.biorxiv.org/content/10.1...
We solved the cryoEM structures of human DNA repair factor MRN bound to DNA and to TRF2. Main work of Yilan, Filiz @filizkuybu.bsky.social and Hengjun. Great collab within the @sfb1361.bsky.social and @genecenter-lmu.bsky.social 🧬🔨
www.biorxiv.org/content/10.1...
Reposted by Prateek Yadav
Our paper sheding light on the antigenic selection mechanism in Trypanosoma brucei is out! 🥳
Check it out!🤓
Check it out!🤓
If you are interested in antigenic variation, you may have wondered how parasites ‘select’ which antigen to express next.
Our manuscript, just published in Nature, provides some answers!
www.nature.com/articles/s41...
@lmumuenchen.bsky.social
@erc.europa.eu a.eu
@nature.com
Our manuscript, just published in Nature, provides some answers!
www.nature.com/articles/s41...
@lmumuenchen.bsky.social
@erc.europa.eu a.eu
@nature.com
March 12, 2025 at 6:14 PM
Our paper sheding light on the antigenic selection mechanism in Trypanosoma brucei is out! 🥳
Check it out!🤓
Check it out!🤓
Reposted by Prateek Yadav
If you are interested in antigenic variation, you may have wondered how parasites ‘select’ which antigen to express next.
Our manuscript, just published in Nature, provides some answers!
www.nature.com/articles/s41...
@lmumuenchen.bsky.social
@erc.europa.eu a.eu
@nature.com
Our manuscript, just published in Nature, provides some answers!
www.nature.com/articles/s41...
@lmumuenchen.bsky.social
@erc.europa.eu a.eu
@nature.com
March 12, 2025 at 4:31 PM
If you are interested in antigenic variation, you may have wondered how parasites ‘select’ which antigen to express next.
Our manuscript, just published in Nature, provides some answers!
www.nature.com/articles/s41...
@lmumuenchen.bsky.social
@erc.europa.eu a.eu
@nature.com
Our manuscript, just published in Nature, provides some answers!
www.nature.com/articles/s41...
@lmumuenchen.bsky.social
@erc.europa.eu a.eu
@nature.com
Reposted by Prateek Yadav
Yesterday, we did a quick spot check, asking our colleagues if they were concerned about current events affecting research freedom. The response was huge-most passers-by expressed their solidarity with the global scientific community 🧪 Imagine if we'd asked more...
#StandUpForScience #ScienceMatters
#StandUpForScience #ScienceMatters
March 12, 2025 at 8:54 AM
Yesterday, we did a quick spot check, asking our colleagues if they were concerned about current events affecting research freedom. The response was huge-most passers-by expressed their solidarity with the global scientific community 🧪 Imagine if we'd asked more...
#StandUpForScience #ScienceMatters
#StandUpForScience #ScienceMatters
Reposted by Prateek Yadav
Epigenetics Gordon Research Conference. Consider joining us for what will be an excellent, exciting meeting and will be held in Europe for the first time: 10-15 Aug25 Barcelona, Spain. Please repost and apply early - this meeting is popular! www.grc.org/epigenetics-...
2025 Epigenetics Conference GRC
The 2025 Gordon Research Conference on Epigenetics will be held in Castelldefels, Barcelona Spain. Apply today to reserve your spot.
www.grc.org
February 25, 2025 at 4:54 PM
Epigenetics Gordon Research Conference. Consider joining us for what will be an excellent, exciting meeting and will be held in Europe for the first time: 10-15 Aug25 Barcelona, Spain. Please repost and apply early - this meeting is popular! www.grc.org/epigenetics-...
Reposted by Prateek Yadav
Here it is... an amazing team effort from 3 Masters students and collaborators! Thanks to reviewers for constructive comments. Plasmids available here: www.addgene.org/search/catal...
royalsocietypublishing.org/doi/10.1098/...
royalsocietypublishing.org/doi/10.1098/...
A high-throughput protein tagging toolkit that retains endogenous untranslated regions for studying gene regulation in kinetoplastids | Open Biology
Kinetoplastid parasites cause diseases that threaten human and animal health. To survive
transitions between vertebrate hosts and insect vectors, these parasites rely on precise
regulation of gene exp...
royalsocietypublishing.org
February 26, 2025 at 7:28 AM
Here it is... an amazing team effort from 3 Masters students and collaborators! Thanks to reviewers for constructive comments. Plasmids available here: www.addgene.org/search/catal...
royalsocietypublishing.org/doi/10.1098/...
royalsocietypublishing.org/doi/10.1098/...
Reposted by Prateek Yadav
📢 Abstract submissions for student talks for 2025 have officially closed! We'd like to massively thank you for all your submissions!
By popular request, we have extended the submissions for posters abstracts by an extra week!
Sign up by visiting us at:
www.munich-interact.de/register
By popular request, we have extended the submissions for posters abstracts by an extra week!
Sign up by visiting us at:
www.munich-interact.de/register
February 24, 2025 at 11:49 AM
📢 Abstract submissions for student talks for 2025 have officially closed! We'd like to massively thank you for all your submissions!
By popular request, we have extended the submissions for posters abstracts by an extra week!
Sign up by visiting us at:
www.munich-interact.de/register
By popular request, we have extended the submissions for posters abstracts by an extra week!
Sign up by visiting us at:
www.munich-interact.de/register
Reposted by Prateek Yadav
Happy to share this with you!
Together with the Längst lab (Uni Regensburg) we characterized PfSnf2L as essential regulator for „just in time“ transcription.
A big thanks to our collaboration partners (Marti lab) and Llinas lab (@llinaslab.bsky.social).
www.nature.com/articles/s41...
Together with the Längst lab (Uni Regensburg) we characterized PfSnf2L as essential regulator for „just in time“ transcription.
A big thanks to our collaboration partners (Marti lab) and Llinas lab (@llinaslab.bsky.social).
www.nature.com/articles/s41...
Plasmodium blood stage development requires the chromatin remodeller Snf2L - Nature
Plasmodium falciparum Snf2L is an ISWI-related ATPase that actively repositions P. falciparum nucleosomes in vivo.
www.nature.com
February 19, 2025 at 4:32 PM
Happy to share this with you!
Together with the Längst lab (Uni Regensburg) we characterized PfSnf2L as essential regulator for „just in time“ transcription.
A big thanks to our collaboration partners (Marti lab) and Llinas lab (@llinaslab.bsky.social).
www.nature.com/articles/s41...
Together with the Längst lab (Uni Regensburg) we characterized PfSnf2L as essential regulator for „just in time“ transcription.
A big thanks to our collaboration partners (Marti lab) and Llinas lab (@llinaslab.bsky.social).
www.nature.com/articles/s41...
Reposted by Prateek Yadav
Don’t miss out on this deep dive into protein structure, design, and function—where science meets innovation! 💡
🔗 More info: www.munich-interact.de
#proteindesign #ai #biophysics #deeplearning #keynote #scienceinnovation
🔗 More info: www.munich-interact.de
#proteindesign #ai #biophysics #deeplearning #keynote #scienceinnovation
February 21, 2025 at 10:28 AM
Don’t miss out on this deep dive into protein structure, design, and function—where science meets innovation! 💡
🔗 More info: www.munich-interact.de
#proteindesign #ai #biophysics #deeplearning #keynote #scienceinnovation
🔗 More info: www.munich-interact.de
#proteindesign #ai #biophysics #deeplearning #keynote #scienceinnovation
Reposted by Prateek Yadav
From computational design to wet lab biophysical characterization, he’ll break down how machine learning is revolutionizing protein science—pushing the boundaries of what’s possible beyond nature! 🌍
Interact Munich 2025
PhD conference, interact 2025, organised in Munich, Germany. Great opportunity for PhD candidates to network with fellow early career researchers and learn about their future career opportunities.
www.munich-interact.de
February 21, 2025 at 10:28 AM
From computational design to wet lab biophysical characterization, he’ll break down how machine learning is revolutionizing protein science—pushing the boundaries of what’s possible beyond nature! 🌍
Reposted by Prateek Yadav
We’re thrilled to welcome Prof. Dr. Lukas Milles (@lfmilles.bsky.social) as our keynote speaker! With a background in de novo protein design, deep learning, and biophysics, his talk will dive into the cutting-edge world of AI-driven protein engineering. 🧪
Interact Munich 2025
PhD conference, interact 2025, organised in Munich, Germany. Great opportunity for PhD candidates to network with fellow early career researchers and learn about their future career opportunities.
www.munich-interact.de
February 21, 2025 at 10:28 AM
We’re thrilled to welcome Prof. Dr. Lukas Milles (@lfmilles.bsky.social) as our keynote speaker! With a background in de novo protein design, deep learning, and biophysics, his talk will dive into the cutting-edge world of AI-driven protein engineering. 🧪
Reposted by Prateek Yadav
📣 Deadline coming up soon! Don't forget to register for the INTERACT MUNICH 2025 conference!
📅 3 - 4 April 2025
📍 Biomedical Center (BMC), LMU
💬 Young life scientists
📝 Abstract deadline: 24.02.2025
➡️ lnkd.in/eKcwZJwV
#interact #munich #interact2025 #conference #PhD #Master #Postdoc
📅 3 - 4 April 2025
📍 Biomedical Center (BMC), LMU
💬 Young life scientists
📝 Abstract deadline: 24.02.2025
➡️ lnkd.in/eKcwZJwV
#interact #munich #interact2025 #conference #PhD #Master #Postdoc
February 12, 2025 at 8:46 AM
📣 Deadline coming up soon! Don't forget to register for the INTERACT MUNICH 2025 conference!
📅 3 - 4 April 2025
📍 Biomedical Center (BMC), LMU
💬 Young life scientists
📝 Abstract deadline: 24.02.2025
➡️ lnkd.in/eKcwZJwV
#interact #munich #interact2025 #conference #PhD #Master #Postdoc
📅 3 - 4 April 2025
📍 Biomedical Center (BMC), LMU
💬 Young life scientists
📝 Abstract deadline: 24.02.2025
➡️ lnkd.in/eKcwZJwV
#interact #munich #interact2025 #conference #PhD #Master #Postdoc