🧵 This project is co-lead by Casia Nursyifa as her PhD project, and Xi Wang as her postdoc project. Congratulations to all 31 authors, including the senior authors Rasmus Heller, Bambang Purwantara, & Mohammad Agil.

🧵 The potential of new unique variants that can improve cattle productivity via genomic selection, making them high yield while being adaptive to hot climate, and potentially breed environmentally friendly cattle with low carbon footprint.

🧵 This study reveal ~3.5mio novel genetic variants previously unknown to cattle genomics, where the ones coming from high proportion of banteng ancestry coincides with traits related to coat coloring (Figure 5a & b) and productivity traits, among other things.

🧵 This recent introgression was thought to be the cause of their high genetic diversity (Figure 4d).

🧵 🧬 Genomics also shown that Indonesian cattle came to islands of Indonesia via mainland Southeast Asia as opposed to India where they have been thought to originate. They came in two pulses, Sumatra and Java (Figure 4a).

🧵 🧬 Genomic analyses found that from 7 breeds, 5 were hosting a recent introgression from local wild cattle, banteng, which is listed as Critically Endangered by the IUCN. One breed, Madura cattle, has 36% of its genome from the banteng (Fig 3)

🧵 🧬 Compared to other domestic cattle where genomic data were available, Indonesian cattle hosted more genetic variation and lower level of inbreeding relative to other cattle, especially Madura, Jabres, and Pasundan (Fig 2)

🧵 🧬 We sequenced 126 WGS from 7 breeds 🐂 (Fig 1), revealing a unique evolutionary history and its promise for sustainable cattle #farming.

Day 1 of #EPIC25
@sagitaninta.bsky.social (KU) presented her work on Indonesian cattle and the evolutionary forces shaping their genomic landscape.

Day 1 of #EPIC25
Cool talk by Marta Ciucani (KU) on the giant forest hog and what its #genome reveals about the evolutionary history of its subspecies.

Day 1 of #EPIC25
Nuno Martins (KU) presented his preliminary analyses on the Greenlandic #reindeers

We then continued with Emil Jørsboe (SSI) and explored the genetics of permanent tooth eruption.

Shixu He (KU) gave a brilliant talk about the #metagenome of the Greenland population, revealing unique microbial signatures. Seems like ice-cream can improve your health!?

Congratulations and thanks to all co-authors, especially to the two co-first authors @erillgenis.bsky.social and Shanlin Liu for starting and leading this project and the seniors @aalbrechtsen.bsky.social, Tom Gilbert and Rasmus Heller.