PhoenixMiaoLab@UChicago
phoenixmiao1010.bsky.social
PhoenixMiaoLab@UChicago
@phoenixmiao1010.bsky.social
Assistant professor at University of Chicago, studying stem cell & immune interactions in cancer and tissue regeneration
https://www.themiaolab.com
Pinned
Our recent work demonstrating the superior immune resistance that is rooted in a subset of cancer stem cells.
Adaptive Immune Resistance Emerges from Tumor-Initiating Stem Cells cell.com/cell/fulltex...
Adaptive Immune Resistance Emerges from Tumor-Initiating Stem Cells
A subset of TGF-β-responsive squamous cell carcinoma stem cells are refractory to immunotherapy via expression of CD80, leading to dampening of cytotoxic T cell responses, and these tumor stem cells a...
cell.com
Looking to launch your faculty career during these turbulent times? Join Ben May Dept for Cancer Research and University of Chicago. With the strong support, this is the ideal place to start your journey! #CancerResearch
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July 3, 2025 at 2:11 PM
TODAY WE ALL MARCH FOR SCIENCE!
March 8, 2025 at 12:34 AM
Thrilled to have Jeffrey Rathmell, PhD, as our new chair! The future of our department is bright and strong!
UChicago names Jeffrey Rathmell, PhD, as Chair of the Ben May Department for Cancer Research
Rathmell, a pioneer in immune and cancer cell metabolism research, has been named Chair of the Ben May Department for Cancer Research and Director of the Ludwig Center for Metastasis Research at the U...
biologicalsciences.uchicago.edu
March 4, 2025 at 1:39 AM
Our recent work demonstrating the superior immune resistance that is rooted in a subset of cancer stem cells.
Adaptive Immune Resistance Emerges from Tumor-Initiating Stem Cells cell.com/cell/fulltex...
Adaptive Immune Resistance Emerges from Tumor-Initiating Stem Cells
A subset of TGF-β-responsive squamous cell carcinoma stem cells are refractory to immunotherapy via expression of CD80, leading to dampening of cytotoxic T cell responses, and these tumor stem cells a...
cell.com
November 14, 2024 at 12:25 AM
Thrilled to share our latest review with
@JudithAgudo1
on the unique immune resistance mechanisms of #CancerStemCells in solid tumors! Explore how these insights are reshaping cancer therapy approaches. #Immunology #CancerResearch #CancerImmunotherapy"
www.nature.com/articles/s41...
Stemness in solid malignancies: coping with immune attack - Nature Reviews Cancer
Immunotherapy shows promise in treating cancers by engineering T cells or using antibodies to activate them. However, cancer stem cells (CSCs) resist immunotherapies and drive cancer relapse. In this ...
www.nature.com
November 14, 2024 at 12:19 AM
Our new work is published on Immunity today. We have unveiled a surprising role of epithelial stem cells in mounting a robust Treg response to build a temporary and protective niche during wound repair.
sciencedirect.com/science/arti...
CD80 on skin stem cells promotes local expansion of regulatory T cells upon injury to orchestrate repair within an inflammatory environment
Following tissue damage, epithelial stem cells (SCs) are mobilized to enter the wound, where they confront harsh inflammatory environments that can im…
sciencedirect.com
November 14, 2024 at 12:18 AM