Petra Mocellin
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petramoce.bsky.social
Petra Mocellin
@petramoce.bsky.social
Neuroscientist studying midbrain circuits & motivated behaviors 🔎🧠🐭

novelty | information seeking | Parkinson Disease

EMBO postdoctoral fellow
PostDoc @UCBerkeley - Lammel Lab
PhD @UniBonn - Remy Lab
Huge thanks to Drew Kesner for organizing this panel—despite being Bluesky-less! Wishing the NIH situation was different so he could join us. ⛰️
January 29, 2025 at 10:31 PM
Wow!
December 11, 2024 at 7:59 PM
December 6, 2024 at 3:31 PM
Congrats Sabine! 🤩
December 3, 2024 at 4:44 PM
Me 🙋🏻‍♀️
December 3, 2024 at 4:43 PM
Me too 🙋🏻‍♀️
November 30, 2024 at 5:26 PM
3️⃣ Within the GABAergic population, we identified 6 subclusters in the continuum.

These include:
- PV+ and calretinin+ neurons, confirming prior observations
- NPAS1+/Sst+ neurons, which form a distinctive subpopulation
- Nts expressing neurons, adding to the complexity of the GABA population

4/4
November 20, 2024 at 4:14 PM
2️⃣ ChAT-expressing neurons are better described along a transcriptomic continuum with two distinct endpoints:

- one predominantly expresses Galanin, a neuropeptide largely underexplored
-one co-expresses GABAergic machinery, aligning with the previously reported ChAT-GABA co-releasing neurons

3/n
November 20, 2024 at 4:13 PM
Key findings:

1️⃣ Gad1 and Gad2, traditionally considered specific to GABAergic neurons, also show unexpected expression in ChAT and VGluT2-expressing neurons, challenging established assumptions about neuronal markers in the MSDB.

2/n
November 20, 2024 at 4:13 PM