peterdoohan.bsky.social
@peterdoohan.bsky.social
Reposted
1/ Excited to share that our symposium review covering cognitive mapping in the PFC just came out in the Journal of Neuroscience: www.jneurosci.org/content/45/4...
Cognitive Maps in the Prefrontal Cortex
The prefrontal cortex (PFC) is critical for our ability to rapidly and flexibly adapt our behavior in new environments based on our previous experience. Despite its importance, the neural substrates a...
www.jneurosci.org
November 15, 2025 at 6:03 PM
Reposted
Come join us at #SfN25 for the minisymposium "Cognitive Maps in the Prefrontal Cortex"!
Saturday, Nov 15, 2:00-4:30pm, Room SDCC 6CF
www.abstractsonline.com/pp8/#!/21171...
We will explore how the PFC represents structured relationships across species and how this supports flexible behavior.
November 14, 2025 at 4:48 AM
Reposted
🚨New pre-print!🚨

Can we truly independently read and write neuronal activity at the same time using all-optical techniques? Here we show that even two-photon imaging over large fields of view with low dwell time per cell can bias neural dynamics!

Read on for some potential fixes: (1/5)
Desensitization of opsin responses during all-optical interrogation depends on imaging parameters
Significance The combination of two-photon calcium imaging and two-photon optogenetic stimulation, termed all-optical interrogation, provides spatial and temporal precision when recording and manipula...
www.biorxiv.org
October 15, 2025 at 4:47 PM
Reposted
** We have up to TWO funded PhD positions available in our lab!! Apply below to find new ways to enhance memory👇 Pls retweet **

Deadline: 2nd December

1. Cross-species closed-loopTMR: tinyurl.com/bddu4tp6

2. TUS and TMR in humans:
tinyurl.com/jjws5ctj

Happy to chat to interested applicants.
Enhancing memory using cross-species closed-loop Targeted Memory Reactivation | mrcbndu
tinyurl.com
October 6, 2025 at 11:51 AM
Reposted
Twenty-four years ago today, our paper “A forkhead-domain gene is mutated in a severe speech and language disorder” was published: www.nature.com/articles/350....
A personal thread about the ups & downs of the journey we took to get to that point....1/n
🗣️🧬🧪
October 4, 2025 at 1:34 PM
Reposted
I’m pleased to share our new paper, “Hippocampal ripple diversity organizes neuronal reactivation dynamics in the offline brain”, out in @cp-neuron.bsky.social !

With @vitorlds.bsky.social and David Dupret, we show that diversity in ripple current profiles shapes reactivation dynamics
October 2, 2025 at 3:46 PM
Planning with attractors in PFC!
I’m super excited to finally put my recent work with @behrenstimb.bsky.social on bioRxiv, where we develop a new mechanistic theory of how PFC structures adaptive behaviour using attractor dynamics in space and time!

www.biorxiv.org/content/10.1...
September 24, 2025 at 1:16 PM
Reposted
I’m super excited to finally put my recent work with @behrenstimb.bsky.social on bioRxiv, where we develop a new mechanistic theory of how PFC structures adaptive behaviour using attractor dynamics in space and time!

www.biorxiv.org/content/10.1...
September 24, 2025 at 12:04 PM
Reposted
🚨We believe this is a major step forward in how we study hippocampus function in healthy humans.

Using novel behavioral tasks, fMRI, RL & RNN modeling, and transcranial ultrasound stimulation (TUS), we demonstrate the causal role of hippocampus in relational structure learning.
August 28, 2025 at 2:00 PM
Reposted
Our new paper out now in Science explores how neural activity in the lateral entorhinal cortex (LEC) *drifts* over time - and *jumps* at key boundaries - to help organize events in memory.

🔗 www.science.org/doi/10.1126/...

Here's a quick summary of what we found 🧵👇
June 26, 2025 at 6:15 PM
Reposted
Large-scale projects run the risk of stifling scientific independence. Instead, let’s explore alternative mechanisms of collaboration, writes @neuralreckoning.bsky.social.

#neuroskyence

www.thetransmitter.org/funding/neur...
Neuroscience needs to empower early-career researchers, not fund moon shots
Large-scale projects run the risk of stifling scientific independence. Instead, let’s explore alternative mechanisms of collaboration.
www.thetransmitter.org
May 26, 2025 at 3:40 PM
Reposted
*** Come join us !! We are recruiting !! ***
How does the brain generate beliefs that go beyond direct experience? How do these mechanisms go awry in psychosis?

The Barron lab tinyurl.com/bdf4drjf @MRCBNDU @NDCNOxford are recruiting a new postdoc tinyurl.com/ut4vbwt4 to work in mouse models
Barron Group | mrcbndu
Our group investigates how cells and circuits in the brain work together to perform computations that support memory. Using a wide range of technical approaches, we investigate how these computations ...
tinyurl.com
May 13, 2025 at 11:01 AM
Reposted
This is not to be missed. You’ll spend your day trying to make RNNs psychotic. And we’ll pay you for it!
May 9, 2025 at 6:16 PM
Reposted
"Science is an investment.

We will put forward a new 500 million package for 2025-2027 to support the best and the brightest researchers and scientists from Europe and around the world."

— President @vonderleyen.ec.europa.eu at the ‘Choose Europe for Science' event at La Sorbonne 🇫🇷
May 5, 2025 at 10:16 AM
Reposted
How do cognitive maps fail? And how can this help us understand/treat psychosis? My lab at @oxexppsy.bsky.social is hiring a Postdoc tinyurl.com/2p935hhz and RA tinyurl.com/3myfpb78 to answer these questions in mouse models.
Here's why you might want to join: 🧵
April 8, 2025 at 10:54 AM
Reposted
Happy to share the latest version of our work on compositional maps in hippocampus with Jo Warren, @jcrwhittington.bsky.social, @behrenstimb.bsky.social. We propose hippocampus constructs maps from cortical building blocks in replay – now with empirical support! www.nature.com/articles/s41... 1/9
Constructing future behavior in the hippocampal formation through composition and replay - Nature Neuroscience
A model of compositional state spaces in the hippocampus shows latent learning and rapid generalization. Bakermans et al. show that this model predicts the emergence of place responses in replay.
www.nature.com
March 17, 2025 at 10:48 AM
Reposted
I wrote an introduction to RL for neuroscience last year that was just published in NBDT: tinyurl.com/5f58zdy3

This review aims to provide some intuition for and derivations of RL methods commonly used in systems neuroscience, ranging from TD learning through the SR to deep and distributional RL!
An introduction to reinforcement learning for neuroscience | Published in Neurons, Behavior, Data analysis, and Theory
By Kristopher T. Jensen. Reinforcement learning for neuroscientists
tinyurl.com
December 21, 2024 at 5:59 PM
Reposted
Our paper "Memory reactivation generates new, adaptive behaviours that reach beyond direct experience" is now out www.nature.com/articles/s41...! With Annie Rawson, Jill O’Reilly and Helen Barron at MRC BNDU @ndcnoxford.bsky.social 1/6
December 13, 2024 at 4:26 PM