Jonathan Keats, PhD 🇨🇦
@pedalheadphx.bsky.social
🇨🇦 boiling in the Arizona desert and not riding my bikes enough. Cancer researcher focused on multiple myeloma and clinical genomics at TGen, part of City of Hope. Creator of MyelomaSky and Sequencing Tech feeds. Director, Collaborative Sequencing Center
For it to work you need high molecular weight DNA going in. But it is a very easy prep, just load DNA on the cartridge, hope the workflow gets deployed to the Dragen appliances on the NovaSeq X
October 22, 2025 at 3:51 PM
For it to work you need high molecular weight DNA going in. But it is a very easy prep, just load DNA on the cartridge, hope the workflow gets deployed to the Dragen appliances on the NovaSeq X
Lots of very good treatments available today. Try to get to a center with a myeloma specialist if possible. Easiest suggestion without knowing location is to find the closest NCI designated comprehensive cancer center. The @imfmyeloma.bsky.social and @themmrf.bsky.social have good resources
October 9, 2025 at 6:07 PM
Lots of very good treatments available today. Try to get to a center with a myeloma specialist if possible. Easiest suggestion without knowing location is to find the closest NCI designated comprehensive cancer center. The @imfmyeloma.bsky.social and @themmrf.bsky.social have good resources
Absolutely agree and you started with one of my pet peeves of the random XY distribution that is clearly BS and gets a good R2 or even worse 0.33 but with some damn pValue < 0.05 that gets a random paint splatter in a published paper as biological truth
October 2, 2025 at 3:03 PM
Absolutely agree and you started with one of my pet peeves of the random XY distribution that is clearly BS and gets a good R2 or even worse 0.33 but with some damn pValue < 0.05 that gets a random paint splatter in a published paper as biological truth
Reposted by Jonathan Keats, PhD 🇨🇦
Thank you Tommy!
The link you gave is good but points to a 2yr old rendering. This one uses recent versions of R and all packages and has all the latest typo fixes:
www.huber.embl.de/msmb/
The link you gave is good but points to a 2yr old rendering. This one uses recent versions of R and all packages and has all the latest typo fixes:
www.huber.embl.de/msmb/
Modern Statistics for Modern Biology
If you are a biologist and want to get the best out of the powerful methods of modern computational statistics, this is your book.
www.huber.embl.de
August 29, 2025 at 1:48 PM
Thank you Tommy!
The link you gave is good but points to a 2yr old rendering. This one uses recent versions of R and all packages and has all the latest typo fixes:
www.huber.embl.de/msmb/
The link you gave is good but points to a 2yr old rendering. This one uses recent versions of R and all packages and has all the latest typo fixes:
www.huber.embl.de/msmb/
Hard day I suspect. If that ends up being the diagnosis make sure to find a reputable myeloma center, outcomes are so much better now overall but management and outcomes are better in centers with disease experts
July 31, 2025 at 10:36 PM
Hard day I suspect. If that ends up being the diagnosis make sure to find a reputable myeloma center, outcomes are so much better now overall but management and outcomes are better in centers with disease experts