Paul Chammas
paulchammas.bsky.social
Paul Chammas
@paulchammas.bsky.social
Postdoc in the Percharde lab @ MRC-LMS.
Happy to see this finally out! Incredible effort from @notquitesincere.bsky.social to push it over the line!💪
Finally out on @devbiol.bsky.social‬: we find that Epop mutant mice have near-perfect Polycomb phenotype (orderly posterior shift of vertebral identity🩻) linked to accelerated HOX clock⏰.

Bonus: Epop has maternal effect!

Study co-led by the the labs of Bernie Payer and @lucianodicroce.bsky.social
The PRC2-associated factor EPOP is required for Hox gene regulation during axial development in mice
The Polycomb repressive complex 2 (PRC2) is an essential modulator of gene repression. We previously reported that, in mouse embryonic stem cells, PRC…
www.sciencedirect.com
August 26, 2025 at 1:40 PM
Reposted by Paul Chammas
It’s official 🎉 I am excited to share that I will start my lab this spring at the Max Planck Institute for Immunobiology and Epigenetics @mpi-ie.bsky.social in beautiful Freiburg 🤩🗻☀️ I am looking forward to new collaborations and working with the fantastic community in Freiburg & its surroundings!
January 16, 2025 at 6:38 PM
Reposted by Paul Chammas
Happy to share our first #bluetorial & our latest #preprint, lead by postdoc @paulchammas.bsky.social. We used CRISPRa to disentangle the close relationship between Dux and MERVL elements in the induction of the 2-cell like state: #TEsky #MERVL www.biorxiv.org/content/10.1... (1/8)
November 26, 2024 at 1:45 PM