My take away was that this was *not* saying "no new funding of animal only research" but rather that NIH will not release new NOFOs that are animal-only and that NOFOs need to consider non-animal methods...I think (hope) the drug discovery trends news piece is over-extrapolating.

I tried something similar using ChatGPT 4.o.

"I'm trying to put together a portfolio of three to five papers to highlight my breadth and depth as a research scientist. (I'm Carl Bergstrom.)

Could you help me choose papers?"

Here's the result.

Not so - apps are being rejected without review if the justification is missing, rather than missing info being requested at JIT, which was the case in the past.

Safwan Hyder (a former MD/PhD student) and Willian Lazarini Lopes (a current postdoc) demonstrate a striking bi-directional modulation of seizures when they silenced and activated dorsal striatum. This effect was present in models of focal and generalized seizures.

NIEHS - 22 April, to be published tomorrow (public-inspection.federalregister.gov/2025-05015.pdf)

NINDS - 10 April, to be published tomorrow
(public-inspection.federalregister.gov/2025-05025.pdf)

NIAMSD - 21 April, to be published tomorrow
(public-inspection.federalregister.gov/2025-04968.pdf)