Pablo Laborda
@pablolaborda.bsky.social
Postdoctoral researcher at DTU | Ecology and evolution of antibiotic resistance and infection microbiology of Pseudomonas aeruginosa
Reposted by Pablo Laborda
Everything you need to explain antimicrobial resistance to family and friends, also in Spanish-5
@pablolaborda.bsky.social
How we can fight AMR
imili.org/new_gallerie...
@sbigot.bsky.social
@pablolaborda.bsky.social
How we can fight AMR
imili.org/new_gallerie...
@sbigot.bsky.social
November 11, 2025 at 12:23 PM
Everything you need to explain antimicrobial resistance to family and friends, also in Spanish-5
@pablolaborda.bsky.social
How we can fight AMR
imili.org/new_gallerie...
@sbigot.bsky.social
@pablolaborda.bsky.social
How we can fight AMR
imili.org/new_gallerie...
@sbigot.bsky.social
Reposted by Pablo Laborda
Everything you need to explain antimicrobial resistance to family and friends, also in Spanish-6
@pablolaborda.bsky.social, @crisherencias.bsky.social
How we can fight AMR
imili.org/pdf/Antimicr...
@pablolaborda.bsky.social, @crisherencias.bsky.social
How we can fight AMR
imili.org/pdf/Antimicr...
November 11, 2025 at 12:27 PM
Everything you need to explain antimicrobial resistance to family and friends, also in Spanish-6
@pablolaborda.bsky.social, @crisherencias.bsky.social
How we can fight AMR
imili.org/pdf/Antimicr...
@pablolaborda.bsky.social, @crisherencias.bsky.social
How we can fight AMR
imili.org/pdf/Antimicr...
Reposted by Pablo Laborda
Everything you need to explain antimicrobial resistance to family and friends, also in Spanish-7
@pablolaborda.bsky.social
@crisherencias.bsky.social
How we can fight AMR
imili.org/pdf/Antimicr...
@pablolaborda.bsky.social
@crisherencias.bsky.social
How we can fight AMR
imili.org/pdf/Antimicr...
November 11, 2025 at 12:30 PM
Everything you need to explain antimicrobial resistance to family and friends, also in Spanish-7
@pablolaborda.bsky.social
@crisherencias.bsky.social
How we can fight AMR
imili.org/pdf/Antimicr...
@pablolaborda.bsky.social
@crisherencias.bsky.social
How we can fight AMR
imili.org/pdf/Antimicr...
Reposted by Pablo Laborda
Everything you need to explain antimicrobial resistance to family and friends, also in Spanish-8
@pablolaborda.bsky.social
@crisherencias.bsky.social
How it works
imili.org/pdf/Antimicr...
@pablolaborda.bsky.social
@crisherencias.bsky.social
How it works
imili.org/pdf/Antimicr...
November 11, 2025 at 12:46 PM
Everything you need to explain antimicrobial resistance to family and friends, also in Spanish-8
@pablolaborda.bsky.social
@crisherencias.bsky.social
How it works
imili.org/pdf/Antimicr...
@pablolaborda.bsky.social
@crisherencias.bsky.social
How it works
imili.org/pdf/Antimicr...
Reposted by Pablo Laborda
Everything you need to explain antimicrobial resistance to family and friends, also in Spanish-9
@pablolaborda.bsky.social
@crisherencias.bsky.social
How it works
imili.org/pdf/Antimicr...
@pablolaborda.bsky.social
@crisherencias.bsky.social
How it works
imili.org/pdf/Antimicr...
November 11, 2025 at 12:50 PM
Everything you need to explain antimicrobial resistance to family and friends, also in Spanish-9
@pablolaborda.bsky.social
@crisherencias.bsky.social
How it works
imili.org/pdf/Antimicr...
@pablolaborda.bsky.social
@crisherencias.bsky.social
How it works
imili.org/pdf/Antimicr...
Reposted by Pablo Laborda
Everything you need to explain antimicrobial resistance to family and friends, also in Spanish-4
@pablolaborda.bsky.social
imili.org/pdf/Antimicr...
@pablolaborda.bsky.social
imili.org/pdf/Antimicr...
November 7, 2025 at 4:20 PM
Everything you need to explain antimicrobial resistance to family and friends, also in Spanish-4
@pablolaborda.bsky.social
imili.org/pdf/Antimicr...
@pablolaborda.bsky.social
imili.org/pdf/Antimicr...
Reposted by Pablo Laborda
Everything you need to explain antimicrobial resistance to family and friends, also in Spanish-3
@pablolaborda.bsky.social
imili.org/pdf/Antimicr...
@pablolaborda.bsky.social
imili.org/pdf/Antimicr...
November 7, 2025 at 4:18 PM
Everything you need to explain antimicrobial resistance to family and friends, also in Spanish-3
@pablolaborda.bsky.social
imili.org/pdf/Antimicr...
@pablolaborda.bsky.social
imili.org/pdf/Antimicr...
Reposted by Pablo Laborda
Everything you need to explain antimicrobial resistance to family and friends, also in Spanish-2
@pablolaborda.bsky.social
imili.org/pdf/Antimicr...
@pablolaborda.bsky.social
imili.org/pdf/Antimicr...
November 7, 2025 at 4:16 PM
Everything you need to explain antimicrobial resistance to family and friends, also in Spanish-2
@pablolaborda.bsky.social
imili.org/pdf/Antimicr...
@pablolaborda.bsky.social
imili.org/pdf/Antimicr...
Reposted by Pablo Laborda
Everything you need to explain antimicrobial resistance to family and friends, also in Spanish-1
@pablolaborda.bsky.social
imili.org/pdf/Antimicr...
@pablolaborda.bsky.social
imili.org/pdf/Antimicr...
November 7, 2025 at 4:10 PM
Everything you need to explain antimicrobial resistance to family and friends, also in Spanish-1
@pablolaborda.bsky.social
imili.org/pdf/Antimicr...
@pablolaborda.bsky.social
imili.org/pdf/Antimicr...
New preprint out! 📣🚨
We found that loss-of-function mutations in the carbapenem entry porin OprD of Pseudomonas aeruginosa do more than confer #AntibioticResistance: they reshape the bacterial membrane and interaction with the host, enhancing epithelial colonization capacity 🦠
#Microsky
We found that loss-of-function mutations in the carbapenem entry porin OprD of Pseudomonas aeruginosa do more than confer #AntibioticResistance: they reshape the bacterial membrane and interaction with the host, enhancing epithelial colonization capacity 🦠
#Microsky
Carbapenem-resistance oprD mutations reshape Pseudomonas aeruginosa host-pathogen interactions during infection https://www.biorxiv.org/content/10.1101/2025.10.24.684370v1
October 25, 2025 at 12:29 PM
New preprint out! 📣🚨
We found that loss-of-function mutations in the carbapenem entry porin OprD of Pseudomonas aeruginosa do more than confer #AntibioticResistance: they reshape the bacterial membrane and interaction with the host, enhancing epithelial colonization capacity 🦠
#Microsky
We found that loss-of-function mutations in the carbapenem entry porin OprD of Pseudomonas aeruginosa do more than confer #AntibioticResistance: they reshape the bacterial membrane and interaction with the host, enhancing epithelial colonization capacity 🦠
#Microsky
Reposted by Pablo Laborda
We just opened the Bluesky account of the International Microbiology Literacy Initiative (IMiLI) headed by Ken Timmis. Follow us to know more about the initiative or even better become one of our volunteers to bring Microbiology to kids all ages around the world 🦠 🏫
Welcome to the social media account of the International Microbiology Literacy Initiative (IMiLI). Nearly 1,000 researchers freely contribute to the IMiLI project integrating microbiology into education providing downloadable resources for all. Explore at imili.org
September 23, 2025 at 7:19 PM
We just opened the Bluesky account of the International Microbiology Literacy Initiative (IMiLI) headed by Ken Timmis. Follow us to know more about the initiative or even better become one of our volunteers to bring Microbiology to kids all ages around the world 🦠 🏫
Reposted by Pablo Laborda
Welcome to the social media account of the International Microbiology Literacy Initiative (IMiLI). Nearly 1,000 researchers freely contribute to the IMiLI project integrating microbiology into education providing downloadable resources for all. Explore at imili.org
September 23, 2025 at 6:45 PM
Welcome to the social media account of the International Microbiology Literacy Initiative (IMiLI). Nearly 1,000 researchers freely contribute to the IMiLI project integrating microbiology into education providing downloadable resources for all. Explore at imili.org
Reposted by Pablo Laborda
This work is finally published! 🥳🧬
Plasmids are associated with very variable fitness costs in their different bacterial hosts. But, what is the contribution of each of the plasmid-genes in these host-specific effects? Study led by
@jorgesastred.bsky.social, @sanmillan.bsky.social and myself! 1/14
Plasmids are associated with very variable fitness costs in their different bacterial hosts. But, what is the contribution of each of the plasmid-genes in these host-specific effects? Study led by
@jorgesastred.bsky.social, @sanmillan.bsky.social and myself! 1/14
Dissecting pOXA-48 fitness effects in clinical Enterobacterales using plasmid-wide CRISPRi screens
Nature Communications - This study investigates the effects of the carbapenem resistance plasmid pOXA-48 in clinical enterobacteria. Using CRISPRi screens, the authors revealed that the...
rdcu.be
August 20, 2025 at 1:25 PM
This work is finally published! 🥳🧬
Plasmids are associated with very variable fitness costs in their different bacterial hosts. But, what is the contribution of each of the plasmid-genes in these host-specific effects? Study led by
@jorgesastred.bsky.social, @sanmillan.bsky.social and myself! 1/14
Plasmids are associated with very variable fitness costs in their different bacterial hosts. But, what is the contribution of each of the plasmid-genes in these host-specific effects? Study led by
@jorgesastred.bsky.social, @sanmillan.bsky.social and myself! 1/14
Reposted by Pablo Laborda
New paper out! 🔈🔈📣📣
Plasmids promote antimicrobial resistance through Insertion Sequence-mediated gene inactivation.
Combining experimental and computational approaches, we unveil how two of the most prevalent bacterial MGE accelerate the evolution of AMR. 🧵👇🏻
www.biorxiv.org/content/10.1...
Plasmids promote antimicrobial resistance through Insertion Sequence-mediated gene inactivation.
Combining experimental and computational approaches, we unveil how two of the most prevalent bacterial MGE accelerate the evolution of AMR. 🧵👇🏻
www.biorxiv.org/content/10.1...
Plasmids promote antimicrobial resistance through Insertion Sequence-mediated gene inactivation
Antimicrobial Resistance (AMR) is a major threat to public health. Plasmids are mobile genetic elements that can rapidly spread across bacterial populations, promoting the dissemination of AMR genes i...
www.biorxiv.org
August 13, 2025 at 6:26 AM
New paper out! 🔈🔈📣📣
Plasmids promote antimicrobial resistance through Insertion Sequence-mediated gene inactivation.
Combining experimental and computational approaches, we unveil how two of the most prevalent bacterial MGE accelerate the evolution of AMR. 🧵👇🏻
www.biorxiv.org/content/10.1...
Plasmids promote antimicrobial resistance through Insertion Sequence-mediated gene inactivation.
Combining experimental and computational approaches, we unveil how two of the most prevalent bacterial MGE accelerate the evolution of AMR. 🧵👇🏻
www.biorxiv.org/content/10.1...
Reposted by Pablo Laborda
Do plasmids evolve faster 🐇, slower 🐢, or just like chromosomes 🧬?
In our new paper, we tackled this question using theory, simulations, bioinformatics, and experiments!
👇 Check out all the details in Paula’s thread!
Hint: 🐇 (most of the time)
In our new paper, we tackled this question using theory, simulations, bioinformatics, and experiments!
👇 Check out all the details in Paula’s thread!
Hint: 🐇 (most of the time)
July 22, 2025 at 3:05 PM
Do plasmids evolve faster 🐇, slower 🐢, or just like chromosomes 🧬?
In our new paper, we tackled this question using theory, simulations, bioinformatics, and experiments!
👇 Check out all the details in Paula’s thread!
Hint: 🐇 (most of the time)
In our new paper, we tackled this question using theory, simulations, bioinformatics, and experiments!
👇 Check out all the details in Paula’s thread!
Hint: 🐇 (most of the time)
Reposted by Pablo Laborda
Our paper “Global dissemination of npmA mediated pan‑aminoglycoside resistance via a mobile element in Gram‑positive bacteria” is now in @natcomms.nature.com. Part of my freshly defended PhD, so doubly happy! 😄🎉
🧵 (1/14)
www.doi.org/10.1038/s414...
🧵 (1/14)
www.doi.org/10.1038/s414...
Global dissemination of npmA mediated pan-aminoglycoside resistance via a mobile genetic element in Gram-positive bacteria - Nature Communications
The authors investigate the distribution of the aminoglycoside resistance gene npmA in Gram-positive bacteria via a mobile genetic element, highlighting its global presence and cross-species transfer ...
www.doi.org
July 17, 2025 at 12:13 PM
Our paper “Global dissemination of npmA mediated pan‑aminoglycoside resistance via a mobile element in Gram‑positive bacteria” is now in @natcomms.nature.com. Part of my freshly defended PhD, so doubly happy! 😄🎉
🧵 (1/14)
www.doi.org/10.1038/s414...
🧵 (1/14)
www.doi.org/10.1038/s414...
Reposted by Pablo Laborda
🚨🚨New paper out in @natcomms.nature.com!!
Come for the first large-scale analysis of plasmid copy number across species,
stay for one of the most intriguing results of my lab: universal scaling laws in plasmid biology! 📈🧬
👉 www.nature.com/articles/s41...
Come for the first large-scale analysis of plasmid copy number across species,
stay for one of the most intriguing results of my lab: universal scaling laws in plasmid biology! 📈🧬
👉 www.nature.com/articles/s41...
Universal rules govern plasmid copy number - Nature Communications
Plasmids exhibit a broad range of sizes and copies per cell, and these two parameters appear to be negatively correlated. Here, Ramiro-Martínez et al. analyse the copy number of thousands of diverse b...
www.nature.com
July 2, 2025 at 11:08 AM
🚨🚨New paper out in @natcomms.nature.com!!
Come for the first large-scale analysis of plasmid copy number across species,
stay for one of the most intriguing results of my lab: universal scaling laws in plasmid biology! 📈🧬
👉 www.nature.com/articles/s41...
Come for the first large-scale analysis of plasmid copy number across species,
stay for one of the most intriguing results of my lab: universal scaling laws in plasmid biology! 📈🧬
👉 www.nature.com/articles/s41...
Reposted by Pablo Laborda
Una nueva investigación identifica un mecanismo molecular que interviene en la pérdida de la resistencia bacteriana al antibiótico ciprofloxacino.
📰Lee aquí más información: bit.ly/4mMl2AN
DOI: bit.ly/43uUtbT
📰Lee aquí más información: bit.ly/4mMl2AN
DOI: bit.ly/43uUtbT
June 4, 2025 at 9:50 AM
Una nueva investigación identifica un mecanismo molecular que interviene en la pérdida de la resistencia bacteriana al antibiótico ciprofloxacino.
📰Lee aquí más información: bit.ly/4mMl2AN
DOI: bit.ly/43uUtbT
📰Lee aquí más información: bit.ly/4mMl2AN
DOI: bit.ly/43uUtbT
Reposted by Pablo Laborda
Aquí os cuentan mis compañeras Susana de Lucas y Jennifer Palencia, de Comunicación y Cultura Científica del @cnb-csic.bsky.social, nuestro último trabajo. Describimos una estrategia de base evolutiva para eliminar la resistencia a ciprofloxacino en aislados clínicos de P. aeruginosa. Felices! 🤩
Una nueva investigación identifica un mecanismo molecular que interviene en la pérdida de la resistencia bacteriana al antibiótico ciprofloxacino.
📰Lee aquí más información: bit.ly/4mMl2AN
DOI: bit.ly/43uUtbT
📰Lee aquí más información: bit.ly/4mMl2AN
DOI: bit.ly/43uUtbT
June 4, 2025 at 10:13 AM
Aquí os cuentan mis compañeras Susana de Lucas y Jennifer Palencia, de Comunicación y Cultura Científica del @cnb-csic.bsky.social, nuestro último trabajo. Describimos una estrategia de base evolutiva para eliminar la resistencia a ciprofloxacino en aislados clínicos de P. aeruginosa. Felices! 🤩
Check out this cool collaboration with @hernando-amado.bsky.social, just out in @natcomms.nature.com!
We show that ciprofloxacin resistance rapidly declines in clinical P. aeruginosa strains under drug-free conditions, suggesting that ciprofloxacin restriction periods could help in clinics 🦠🧫
We show that ciprofloxacin resistance rapidly declines in clinical P. aeruginosa strains under drug-free conditions, suggesting that ciprofloxacin restriction periods could help in clinics 🦠🧫
I am very happy to share our latest study on ciprofloxacin resistance instability in P. aeruginosa during periods of drug restriction. A fantastic collaboration @pablolaborda.bsky.social, RuggeroLaRosa, JLMartínez, SørenMolin & HelleJohansen 🥳 @cnb-csic.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Ciprofloxacin resistance rapidly declines in nfxB defective clinical strains of Pseudomonas aeruginosa - Nature Communications
Antimicrobial resistance can decline due to compensatory mutations or genetic reversions to wild-type alleles. Here, the authors analyse the decline of ciprofloxacin resistance in nfxB-defective Pseud...
www.nature.com
June 4, 2025 at 9:38 AM
Check out this cool collaboration with @hernando-amado.bsky.social, just out in @natcomms.nature.com!
We show that ciprofloxacin resistance rapidly declines in clinical P. aeruginosa strains under drug-free conditions, suggesting that ciprofloxacin restriction periods could help in clinics 🦠🧫
We show that ciprofloxacin resistance rapidly declines in clinical P. aeruginosa strains under drug-free conditions, suggesting that ciprofloxacin restriction periods could help in clinics 🦠🧫
Reposted by Pablo Laborda
Ceftazidime-avibactam (a last resort drug) use selects multidrug-resistance and prevents designing collateral sensitivity based therapies against P. aeruginosa (no robust patterns emerge). Happy to see it published! 🥳 @cnb-csic.bsky.social @idisba.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Ceftazidime-avibactam use selects multidrug-resistance and prevents designing collateral sensitivity-based therapies against Pseudomonas aeruginosa - Nature Communications
Ceftazidime-avibactam is a β-lactam/β-lactamase inhibitor combination restricted for the treatment of multidrug-resistant infections of Pseudomonas aeruginosa non-susceptible to ceftazidime and resist...
www.nature.com
April 9, 2025 at 9:47 AM
Ceftazidime-avibactam (a last resort drug) use selects multidrug-resistance and prevents designing collateral sensitivity based therapies against P. aeruginosa (no robust patterns emerge). Happy to see it published! 🥳 @cnb-csic.bsky.social @idisba.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Pablo Laborda
Are you a #Pseudomonas researcher? Please take our survey and help shape the direction and priority of future pseudomonas.com database development: forms.gle/gTPT6ruf3mqb...
#microsky #idsky
#microsky #idsky
The Pseudomonas Genome Database - Genome annotation and comparative genome analysis
pseudomonas.com
February 1, 2025 at 9:34 PM
Are you a #Pseudomonas researcher? Please take our survey and help shape the direction and priority of future pseudomonas.com database development: forms.gle/gTPT6ruf3mqb...
#microsky #idsky
#microsky #idsky
Last month, I had the chance to share my research in my hometown – more than 7 years since I did my bachelor’s degree over there!
Today, the local newspaper @heraldo.es features some insights from the event participants about their research (and life) abroad
www.heraldo.es/noticias/ara...
Today, the local newspaper @heraldo.es features some insights from the event participants about their research (and life) abroad
www.heraldo.es/noticias/ara...
January 27, 2025 at 7:20 AM
Last month, I had the chance to share my research in my hometown – more than 7 years since I did my bachelor’s degree over there!
Today, the local newspaper @heraldo.es features some insights from the event participants about their research (and life) abroad
www.heraldo.es/noticias/ara...
Today, the local newspaper @heraldo.es features some insights from the event participants about their research (and life) abroad
www.heraldo.es/noticias/ara...
Our group is looking for a PostDoc with a strong background in molecular microbiology, strain design and genetic engineering. Join us at DTU to work on bacterial infections and antimicrobial resistance!
www.rigshospitalet.dk/job-og-uddan...
www.rigshospitalet.dk/job-og-uddan...
www.rigshospitalet.dk
January 23, 2025 at 4:27 PM
Our group is looking for a PostDoc with a strong background in molecular microbiology, strain design and genetic engineering. Join us at DTU to work on bacterial infections and antimicrobial resistance!
www.rigshospitalet.dk/job-og-uddan...
www.rigshospitalet.dk/job-og-uddan...
Reposted by Pablo Laborda
⚠️ Job(s) alert! ⚠️
We are launching a new postdoctoral program in Systems Biology at IBFG. Join us!
👉 Several positions available with competitive work conditions for up to 4 years
📄 More info: jdiazc9.github.io/files/jobs/2...
We are launching a new postdoctoral program in Systems Biology at IBFG. Join us!
👉 Several positions available with competitive work conditions for up to 4 years
📄 More info: jdiazc9.github.io/files/jobs/2...
January 17, 2025 at 1:36 PM
⚠️ Job(s) alert! ⚠️
We are launching a new postdoctoral program in Systems Biology at IBFG. Join us!
👉 Several positions available with competitive work conditions for up to 4 years
📄 More info: jdiazc9.github.io/files/jobs/2...
We are launching a new postdoctoral program in Systems Biology at IBFG. Join us!
👉 Several positions available with competitive work conditions for up to 4 years
📄 More info: jdiazc9.github.io/files/jobs/2...