Pedro Santamaria
p-santamaria.bsky.social
Pedro Santamaria
@p-santamaria.bsky.social
Retired researcher in Developmental Genetics, Evo-Devo. Drosophila. Polycomb Group. (PRC genes). Finder of "polyhomeotic", Nuclear transplantation in the egg. Cell mosaics and chimeras. Epigenesis in Drosophila. CSIC --> CNRS. Hobby: mosaics.
Reposted by Pedro Santamaria
In 2009 A.Garcia Bellido asked me to try my hand at a history of #Genetics in Spain. With some reluctance (I am no historian, nor pretend to be one), I obliged ijdb.ehu.eus/article/0828....
He helped me with many conversations and, of course, he had to have a place of honour in it (see Appendix I)
A perspective on the development of Genetics in Spain during the XX Century | The International Journal of Developmental Biology
At the beginning of the XXI Century, Spanish Biology lives a period of unprecedented growth and development. This situation owes much to the stability of the last few years and breaks a pattern in which Science was the activity of a few self-taught individuals working within an indifferent environment. The development of Genetics is a good example of these factors. A long isolated period dating back to the 1500s was broken at the beginning of the XX Century through the creation of a number of institutions and, in particular the Junta de Ampliacion de Estudios, which created a seed for scientific development and had a significant effect in the area of Genetics. However, the Spanish civil war destroyed this seed and forced a new beginning. Throughout the second half of the century, steady progress, largely driven by individuals formed abroad and returning to Spain with knowledge and methods, has been the basis for the establishment of a scientific ingrastructure from which Spain is making important contributions to modern biology. The person of Antonio Garcia-Bellido has emerged over the last 40 years as a reference for modern genetics and also as the root of an important, perhaps the only, real school in this area of work.
ijdb.ehu.eus
November 14, 2025 at 3:45 PM
A memory transcriptome time course reveals essential long-term memory transcription factors in Drosophila melanogaster.

www.nature.com/articles/s41...
A memory transcriptome time course reveals essential long-term memory transcription factors - Nature Communications
Gene expression programs underlying memory are not well understood in Drosophila. Here, authors use mushroom body-specific RNA sequencing to characterize the transcriptional trace of long-term memory ...
www.nature.com
November 14, 2025 at 9:14 AM
- "Après que Copernic a privé la Terre de son statut de centre de l’Univers, Charles Darwin a privé l’Humanité de tout rôle central dans l’histoire de la vie, de toute finalité dans son émergence. CONTREDISANT ainsi la plupart des Religions".

www.lemonde.fr/sciences-au-...
Savoirs contre croyances au collège et au lycée
Face aux contestations de la science dans les salles de classe, les enseignants sont souvent démunis. Le biologiste Guillaume Lecointre leur propose un manuel pratique d’une grande clarté.
www.lemonde.fr
November 14, 2025 at 9:00 AM
- "It's Donald genetically different" ?
- “There is no need to look to genes to explain why many individuals try to become dictators – the far more pressing question is WHY WE LET THEM.”

www.newscientist.com/article/2504...
Analysing Hitler's DNA for a TV gimmick tells us nothing useful
To understand Adolf Hitler, we need to look at his personal life and the wider societal and historical context - analysing his DNA for a TV gimmick tells us nothing, says Michael Le Page
www.newscientist.com
November 14, 2025 at 8:16 AM
- A day (soon), we (Humans and Sperm Whales), we will meet and we will talk about all these events.

direct.mit.edu/opmi/article...
Vowel- and Diphthong-Like Spectral Patterns in Sperm Whale Codas
Abstract. The sperm whale communication system, consisting of groups of clicks called codas, has been primarily analyzed in terms of the number of clicks and their inter-click timing. This paper repor...
direct.mit.edu
November 14, 2025 at 7:49 AM
- "I Want my future back".
(Nor Isaac Asimov, neither Arthur C. Clarke were rigth).
- La "Posmodernidad" ha dejado un futuro muy distinto a como lo imaginaban aquellos ilustres profetas tecnocientíficos; hoy se rechaza un mundo artificial, y triunfa lo Natural.

www.agenciasinc.es/Reportajes/U...
Un futuro menos futurista: esta es la ciencia que necesitamos para 2050
El mundo de hoy no es el futuro de coches voladores y robots sirvientes que se imaginaba en el siglo pasado, y la visión actual de lo que el progreso debe traernos ha cambiado. Lo que esperamos de la ciencia para las próximas décadas es que encuentren soluciones contra el cambio climático y otras amenazas que ponen en riesgo nuestra supervivencia y la del planeta.
www.agenciasinc.es
November 14, 2025 at 7:35 AM
"Walking out at Divinity avenue". (about Philip Roth). "It taught me something about the world I was yearning to enter into. It taught me that if I was to leave orthodoxy, I was not entering panacea, neither utopia ! I was going out of them".

news.harvard.edu/gazette/stor...
On Philip Roth’s contradictions — Harvard Gazette
In a Harvard talk, his biographer digs into the novelist’s "true loves" and recurring themes — from lust to Jewish life.
news.harvard.edu
November 14, 2025 at 7:17 AM
Again and again: "Trump administration has proposed cutting the research budget of the National Science Foundation by 55 percent, directing remaining funds to a few fields. But BIOINSPITATION (in animals and plants), which has thrived on this funding, may lose out.

www.nytimes.com/interactive/...
How Inventors Find Inspiration in Evolution (Gift Article)
Soft batteries and water-walking robots are among the many creations made possible by studying animals and plants.
www.nytimes.com
November 13, 2025 at 7:47 AM
Continent deepest roots had peeled off like a banana
... Not like fruit flies (they don't "peel" ) !

www.nature.com/articles/s41...
Enriched mantle generated through persistent convective erosion of continental roots - Nature Geoscience
Convective erosion and lateral transport of metasomatized continental keels may generate enriched mantle geochemical domains sampled by oceanic volcanism, according to a geodynamic modelling study.
www.nature.com
November 13, 2025 at 7:35 AM
The Answer is less important (significant) that the Question: "Rather than training conformists who follow their elders down well-worn routes — and possibly to dead ends — the instructors want out-of-the-box thinkers who can blaze new pathways".

news.harvard.edu/gazette/stor...
No one knows the answer, and that’s the point — Harvard Gazette
“Genuinely Hard Problems” pilots novel approach to scientific education.
news.harvard.edu
November 13, 2025 at 7:07 AM
La nuance des opinions ne passe pas auprès des gens à l' idiosincrasie manichéenne. CNews à du succès en France "parce" qu'ils sont manichéens. Et cela parle de "ce peuple".

www.franc-tireur.fr/presse-pares...
Presse paresse, le franc-parler de Caroline Fourest
Parfois, la lassitude étreint l’éditorialiste. Notre métier serait-il de hurler dans le désert ? De pédaler dans une roue qui n’en finit...
www.franc-tireur.fr
November 12, 2025 at 1:58 PM
Here, we are all, yet (more or less ) younger !

www.nature.com/articles/d41...
Want a younger brain? Learn another language
A vast study suggests that being multilingual can slow down cognitive ageing.
www.nature.com
November 12, 2025 at 8:25 AM
The good (wonderful) thing if we found life elsewhere than in our "Earth", is that we will have conclusive arguments to stop believing in "earthlings" Gods. Those born by virgins, or making miracles, mysogynist, or able to sacrifice their sons to their God.

www.newscientist.com/article/2503...
Enceladus’s ocean may be even better for life than we realised
The buried ocean on Saturn’s moon Enceladus seems to be stable across extremely long periods of time, making it an even more promising place to hunt for life
www.newscientist.com
November 12, 2025 at 7:58 AM
Antonio Garcia Bellido. (circa 1969).
November 11, 2025 at 9:25 AM
Antonio Garcia Bellido a muerto ayer. Aqui en una foto de nuestros "Mafia meetings" con grandes "epígonos". Gracias él apredi a hacer investigacuión.
November 11, 2025 at 9:09 AM
Reposted by Pedro Santamaria
Ayer falleció Antonio García-Bellido (1936-2025), a los 89 años, uno de los mayores genéticos de nuestro país, experto en biología del desarrollo y mentor de muchos otros científicos.
@raciencias.bsky.social
rac.es/sobre-nosotr...
@cbm-csic-uam.bsky.social
@csic.es @uam.es @segenetica.bsky.social
November 11, 2025 at 7:14 AM
Vous le savez déjà. Mais ici la version d'Herve Morin, dans "Le Monde". Intéressant la personnalité controversé de J.W.

www.lemonde.fr/disparitions...
James Watson, codécouvreur de la structure en double hélice de l’ADN, est mort à l’âge de 97 ans
Colauréat du Nobel 1962 pour une découverte qui a donné le coup d’envoi de la révolution génétique, l’Américain avait terni son image en minimisant le travail de la cristallographe Rosalind Franklin e...
www.lemonde.fr
November 8, 2025 at 9:05 AM
Genetics of perfect imposters. Color is passed down almost exclusively through the female sex chromosome. A female can mate with any male without losing their adaptation to a specific host, preventing populations from splitting off into different species.

www.science.org/doi/10.1126/...
Genomic architecture of egg mimicry and its consequences for speciation in parasitic cuckoos
Host-parasite arms races facilitate rapid evolution and can fuel speciation. Cuculus cuckoos are deceptive egg mimics that exhibit a broad diversity of counterfeit egg phenotypes, representing host-ad...
www.science.org
November 7, 2025 at 7:18 AM
Reposted by Pedro Santamaria
Ultra-long-range Polycomb-coupled interactions underlie subtype identity of human cortical neurons #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.05.686502v1
November 6, 2025 at 5:01 PM
Reposted by Pedro Santamaria
Epigenetics Update - A PHF19-YTHDC1 condensate switches EZH2-mediated gene suppression to activation for prostate cancer progression bit.ly/3WldyJd

#Epigenetics #Chromatin #ProstateCancer #Cancer
---

High-resolution insights without cell sorting; epigenometech.com
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
bit.ly
November 5, 2025 at 1:02 PM
Reposted by Pedro Santamaria
The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression www.cell.com/cancer-cell...
November 6, 2025 at 3:15 PM