‣ Whooping cough in child patients: assessing immunity levels and B. pertussis genetics to understand the disease transmission and manifestation
‣ Combatting antimicrobial resistance in the community: A comparative analysis and modelling study to identify the most cost-effective approaches

‣ Assessing the impact of Scalable Public Health Empowerment, Research, and Education Sites (SPHERES), a community-based digital health intervention to enhance maternal and newborn health and immunity, and reduce tuberculosis, hypertension and diabetes

Dphil themes:
‣ Care-seeking, treatment and control for dengue: Multispecies ethnography exploring the complex intersection of viruses, prevention programmes and community practices and beliefs
‣ Equation discovery to infer causal relationships in longitudinal data

👉 www.oucru.org/oucru-awarded-wellcome-discovery-award-grant-to-advance-tuberculosis-research/

The project is led by Assoc Prof Thuong Nguyen, Dr Nhat Le at OUCRU, in collaboration with colleagues from the @ox.ac.uk and Francis Crick Institute (UK).

“Understanding how disease and recovery work at the molecular level will help us monitor treatment more effectively and develop more precisely targeted therapies,” said Assoc Prof Thuong Nguyen, OUCRU Head of TB Research Group.

This six-year research aims to: (1) identify new biomarkers for treatment monitoring and (2) novel targets for host-directed therapies.

It will also establish a comprehensive, integrated database, creating a vital resource for future systems biology and precision medicine research in TB.

TB remains one of the world’s deadliest infectious diseases. In 2023, 10.8 million people became ill with TB and around 1.25 million died from it. Vietnam continues to be among the countries with a high TB burden with 182,000 new cases (182/100,000 population) in 2023 (WHO Global TB Report 2024).

www.oucru.org/modra-cohort...

💡 #MODRA (MORU–OUCRU Discovery Research Academy) is a @wellcometrust.bsky.social funded programme to empower rising researchers from South and Southeast Asia to navigate their careers and drive global health impact.

“We want participants to experience the full research cycle - from developing a strong idea to managing a real project,” said Dr Leigh Jones, MODRA Director.

They also learned essential tools for effective and transparent post-grant management, a key step toward leading independent research.

‣ Dissecting the intra-host adaptation of Klebsiella pneumoniae to antibiotic therapy
‣ Tracking antibiotic access and use in the community in Low-and-Middle-Income countries – evaluation of a prospective digital citizen-science surveillance platform

𝗗𝗽𝗵𝗶𝗹 𝘁𝗵𝗲𝗺𝗲𝘀:
‣ Evaluation and development of new diagnostics for tuberculous meningitis
‣ The pathogenesis of TBM and the role of dexamethasone
‣ Wearable devices and AI for detection of cardiovascular complications in patients with infectious diseases in low-resource settings

Join a growing community advancing research on #infectiousdiseases that impact our region and beyond!

www.oucru.org/oucru-contri...

Read the paper: www.thelancet.com/journals/lan...