At #WCPG2025, a thought-provoking talk by Prof. Peter Visscher on the future possibilites of polygenic editing:

If at #WCPG2025, you are welcome to take a look at my poster today at place 44! 😄🧬
Please also feel free to take a handout of my abstract wih you! 😉
The topic is the dependence of MDD genomics on the constellation of common risk factors of MDD:

Fascinated at #WCPG2025 to learn how the variation of a SNP effect over years or even a lifetime, can be modelled in a mixed-effects algorithm:
FEMA-Long by @parekhpravesh.bsky.social

First #ClusterAnalysis, then #GWAS for #MajorDepression within each subgroup:
#Olfactory genes emerge only in females with ⬇️ #Neuroticism, ⬇️ #BodyFat, & ⬆️ #EducationLevel; while #ComplementSystem genes only in females with the opposite, risk pattern; see our paper:
www.nature.com/articles/s41...