Nils Kurzawa
@nkurzawa.bsky.social
Computational biologist.
Views are my own.
Views are my own.
Reposted by Nils Kurzawa
Excited to share our preprint: Polytope, an epitope barcoding system, generating up to 512 unique color codes for in vivo lineage tracing. 🌈🧬 This tech enables spatial fate-mapping with unprecedented clonal and spatial resolution! doi.org/10.1101/2024... #SpatialBiology #LineageTracing #Polytope
Polytope: High-resolution epitope barcoding for in vivo spatial fate-mapping
Tracing the fate of individual cells and their progeny remains a challenging task. While imaging-based fate-mapping provides spatial information, it generally lacks complexity due to limited label div...
doi.org
December 3, 2024 at 9:41 AM
Excited to share our preprint: Polytope, an epitope barcoding system, generating up to 512 unique color codes for in vivo lineage tracing. 🌈🧬 This tech enables spatial fate-mapping with unprecedented clonal and spatial resolution! doi.org/10.1101/2024... #SpatialBiology #LineageTracing #Polytope
Reposted by Nils Kurzawa
Holistic genetic barcoding reveals a lineage tree of tissue macrophage development https://www.biorxiv.org/content/10.1101/2024.11.29.625985v1
Holistic genetic barcoding reveals a lineage tree of tissue macrophage development https://www.biorxiv.org/content/10.1101/2024.11.29.625985v1
Tissue macrophages are crucial for organ development and homeostasis, yet the developmental routes l
www.biorxiv.org
November 30, 2024 at 9:30 PM
Holistic genetic barcoding reveals a lineage tree of tissue macrophage development https://www.biorxiv.org/content/10.1101/2024.11.29.625985v1
Reposted by Nils Kurzawa
Let the new spatial barcoding era begin!
🚨𝐏𝐨𝐥𝐲𝐭𝐨𝐩𝐞 𝐢𝐬 𝐡𝐞𝐫𝐞!
New preprint by my colleague @dpostrach.bsky.social:
𝐏𝐨𝐥𝐲𝐭𝐨𝐩𝐞 uses 𝐮𝐩 𝐭𝐨 𝟓𝟏𝟐 𝐜𝐨𝐥𝐨𝐫𝐬 𝐭𝐨 𝐭𝐫𝐚𝐜𝐞 𝐜𝐥𝐨𝐧𝐞𝐬 𝐢𝐧 𝐬𝐢𝐭𝐮 as they grow, expand and travel. And cheap readout using IBEX.
Can't wait to see all the fields that will profit from this tool!
🚨𝐏𝐨𝐥𝐲𝐭𝐨𝐩𝐞 𝐢𝐬 𝐡𝐞𝐫𝐞!
New preprint by my colleague @dpostrach.bsky.social:
𝐏𝐨𝐥𝐲𝐭𝐨𝐩𝐞 uses 𝐮𝐩 𝐭𝐨 𝟓𝟏𝟐 𝐜𝐨𝐥𝐨𝐫𝐬 𝐭𝐨 𝐭𝐫𝐚𝐜𝐞 𝐜𝐥𝐨𝐧𝐞𝐬 𝐢𝐧 𝐬𝐢𝐭𝐮 as they grow, expand and travel. And cheap readout using IBEX.
Can't wait to see all the fields that will profit from this tool!
Polytope: High-resolution epitope barcoding for in vivo spatial fate-mapping https://www.biorxiv.org/content/10.1101/2024.11.20.624484v1
Polytope: High-resolution epitope barcoding for in vivo spatial fate-mapping https://www.biorxiv.org/content/10.1101/2024.11.20.624484v1
Tracing the fate of individual cells and their progeny remains a challenging task. While imaging-bas
www.biorxiv.org
December 1, 2024 at 10:45 PM
Let the new spatial barcoding era begin!
🚨𝐏𝐨𝐥𝐲𝐭𝐨𝐩𝐞 𝐢𝐬 𝐡𝐞𝐫𝐞!
New preprint by my colleague @dpostrach.bsky.social:
𝐏𝐨𝐥𝐲𝐭𝐨𝐩𝐞 uses 𝐮𝐩 𝐭𝐨 𝟓𝟏𝟐 𝐜𝐨𝐥𝐨𝐫𝐬 𝐭𝐨 𝐭𝐫𝐚𝐜𝐞 𝐜𝐥𝐨𝐧𝐞𝐬 𝐢𝐧 𝐬𝐢𝐭𝐮 as they grow, expand and travel. And cheap readout using IBEX.
Can't wait to see all the fields that will profit from this tool!
🚨𝐏𝐨𝐥𝐲𝐭𝐨𝐩𝐞 𝐢𝐬 𝐡𝐞𝐫𝐞!
New preprint by my colleague @dpostrach.bsky.social:
𝐏𝐨𝐥𝐲𝐭𝐨𝐩𝐞 uses 𝐮𝐩 𝐭𝐨 𝟓𝟏𝟐 𝐜𝐨𝐥𝐨𝐫𝐬 𝐭𝐨 𝐭𝐫𝐚𝐜𝐞 𝐜𝐥𝐨𝐧𝐞𝐬 𝐢𝐧 𝐬𝐢𝐭𝐮 as they grow, expand and travel. And cheap readout using IBEX.
Can't wait to see all the fields that will profit from this tool!