Francis Lynn 🇨🇦
@nictitate.bsky.social
Reposted by Francis Lynn 🇨🇦
The Evoke trials have (once again) humbled many of us, reminding the field that "paving the way for incretin-based therapies as a future cornerstone in the management of neurodegenerative disorders" is a far more challenging task then originally envisioned #Alzheimers disease
#Throwback 🧪
REVIEW | Incretin-based therapeutics for the treatment of neurodegenerative diseases
@clemmensenc.bsky.social et al
REVIEW | Incretin-based therapeutics for the treatment of neurodegenerative diseases
@clemmensenc.bsky.social et al
Incretin-based therapeutics for the treatment of neurodegenerative diseases - Nature Metabolism
This Review summarizes preclinical and clinical evidence highlighting the potential of incretin-based drugs as treatments of neurodegenerative diseases, such as Alzheimer’s disease or Parkinson’s disease.
bit.ly
November 29, 2025 at 10:14 PM
The Evoke trials have (once again) humbled many of us, reminding the field that "paving the way for incretin-based therapies as a future cornerstone in the management of neurodegenerative disorders" is a far more challenging task then originally envisioned #Alzheimers disease
Reposted by Francis Lynn 🇨🇦
Worked with a great team to organize @keystoneSymposia.bsky.social Fueling #MASH : #Metabolic Drivers & #Inflammatory Crosstalk, this April! Join us to explore emerging research in Vancouver! keysym.us/KSMASH26 #KSMASH26
Early Registration and Abstract deadline is in less than 2 weeks!
Early Registration and Abstract deadline is in less than 2 weeks!
Fueling MASH: Metabolic Drivers and Inflammatory Crosstalk | Keystone Symposia
Join us at the Keystone Symposia on Fueling MASH: Metabolic Drivers and Inflammatory Crosstalk, April 2026, in Vancouver, with field leaders!
keysym.us
November 28, 2025 at 2:59 PM
Worked with a great team to organize @keystoneSymposia.bsky.social Fueling #MASH : #Metabolic Drivers & #Inflammatory Crosstalk, this April! Join us to explore emerging research in Vancouver! keysym.us/KSMASH26 #KSMASH26
Early Registration and Abstract deadline is in less than 2 weeks!
Early Registration and Abstract deadline is in less than 2 weeks!
Zero means zero fun, zero community. vancouversun.com/news/local-n...
'The numbers don't add up:' Vancouver's Celebration of Light cancelled due to funding shortfall
The beloved summer tradition has been scrapped because of a lack of funds
vancouversun.com
November 26, 2025 at 3:41 PM
Zero means zero fun, zero community. vancouversun.com/news/local-n...
Reposted by Francis Lynn 🇨🇦
Islet Biologists in 🇨🇦 🏆 @cirtn.bsky.social
November 26, 2025 at 3:45 AM
Islet Biologists in 🇨🇦 🏆 @cirtn.bsky.social
I hope the provincial government takes this into account when setting rent increases in 2026
zero means -2% (inflation rate predicted to be 2% this year)
Vancouver's 2026 draft budget has PASSED.
Approved on a 7-4 vote on party lines, with ABC in favour and councillors Fry/Bligh/Orr/Maloney opposed.
Property tax freeze, $50 million more for VPD, and cuts to Arts, Culture, Planning and Sustainability departments, among others.
Full story to come.
Approved on a 7-4 vote on party lines, with ABC in favour and councillors Fry/Bligh/Orr/Maloney opposed.
Property tax freeze, $50 million more for VPD, and cuts to Arts, Culture, Planning and Sustainability departments, among others.
Full story to come.
November 25, 2025 at 10:26 PM
I hope the provincial government takes this into account when setting rent increases in 2026
zero means -2% (inflation rate predicted to be 2% this year)
Vancouver's 2026 draft budget has PASSED.
Approved on a 7-4 vote on party lines, with ABC in favour and councillors Fry/Bligh/Orr/Maloney opposed.
Property tax freeze, $50 million more for VPD, and cuts to Arts, Culture, Planning and Sustainability departments, among others.
Full story to come.
Approved on a 7-4 vote on party lines, with ABC in favour and councillors Fry/Bligh/Orr/Maloney opposed.
Property tax freeze, $50 million more for VPD, and cuts to Arts, Culture, Planning and Sustainability departments, among others.
Full story to come.
November 25, 2025 at 10:25 PM
zero means -2% (inflation rate predicted to be 2% this year)
Reposted by Francis Lynn 🇨🇦
Huge congratulations to my friend, @jimjohnsonsci.bsky.social on winning the @cirtn.bsky.social Mentorship Award at yesterday's workshop. Reading his nominations was so heartwarming!
These events make me so excited about working in science in Canada. @nictitate.bsky.social
These events make me so excited about working in science in Canada. @nictitate.bsky.social
November 25, 2025 at 5:45 PM
Huge congratulations to my friend, @jimjohnsonsci.bsky.social on winning the @cirtn.bsky.social Mentorship Award at yesterday's workshop. Reading his nominations was so heartwarming!
These events make me so excited about working in science in Canada. @nictitate.bsky.social
These events make me so excited about working in science in Canada. @nictitate.bsky.social
Reposted by Francis Lynn 🇨🇦
Every machine in a Hospital that diagnoses your body without cutting you open is based on a principle of Physics, discovered by a Physicist who had no interest in Medicine.
If you think the world doesn’t need Basic Science, or that somehow Science has failed you, think again.
#sciencematters
If you think the world doesn’t need Basic Science, or that somehow Science has failed you, think again.
#sciencematters
November 25, 2025 at 1:40 AM
Every machine in a Hospital that diagnoses your body without cutting you open is based on a principle of Physics, discovered by a Physicist who had no interest in Medicine.
If you think the world doesn’t need Basic Science, or that somehow Science has failed you, think again.
#sciencematters
If you think the world doesn’t need Basic Science, or that somehow Science has failed you, think again.
#sciencematters
COP30 - another year of disappointment
November 21, 2025 at 4:09 PM
COP30 - another year of disappointment
Reposted by Francis Lynn 🇨🇦
“One mile on a bike is a $.42 economic gain to society, one mile driving is a $.20 loss.”
“Which means that Copenhagen, a city of 1.2 million people, saves $357 million a year on health costs because something like 80% of its population commutes by bike.” #CityMakingMath
Some costs aren’t costs.
“Which means that Copenhagen, a city of 1.2 million people, saves $357 million a year on health costs because something like 80% of its population commutes by bike.” #CityMakingMath
Some costs aren’t costs.
One mile on a bike is a $.42 economic gain to society, one mile driving is a $.20 loss
Copenhagen, the bicycle-friendliest place on the planet, publishes a biannual Bicycle Account, and buried in its pages is a rather astonishing fact.
grist.org
November 21, 2025 at 12:40 AM
“One mile on a bike is a $.42 economic gain to society, one mile driving is a $.20 loss.”
“Which means that Copenhagen, a city of 1.2 million people, saves $357 million a year on health costs because something like 80% of its population commutes by bike.” #CityMakingMath
Some costs aren’t costs.
“Which means that Copenhagen, a city of 1.2 million people, saves $357 million a year on health costs because something like 80% of its population commutes by bike.” #CityMakingMath
Some costs aren’t costs.
Reposted by Francis Lynn 🇨🇦
📢🎉New study from our lab on circulating SASP factors suggests a novel senescent cell biomarker across #T1D stages! Congrats🥳Camille Jasmine and @dream-diabetes.bsky.social trainees Grateful to TrialNet @chrimanitoba.bsky.social @cirtn.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Circulating senescence-associated secretory phenotype factors across the stages of type 1 diabetes in a cross-sectional cohort - Scientific Reports
Scientific Reports - Circulating senescence-associated secretory phenotype factors across the stages of type 1 diabetes in a cross-sectional cohort
www.nature.com
November 20, 2025 at 4:28 PM
📢🎉New study from our lab on circulating SASP factors suggests a novel senescent cell biomarker across #T1D stages! Congrats🥳Camille Jasmine and @dream-diabetes.bsky.social trainees Grateful to TrialNet @chrimanitoba.bsky.social @cirtn.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Francis Lynn 🇨🇦
Missed my number being called tonight (#609) to speak via phone to Vancouver City Council during their multi-night meeting on the city’s very controversial 0% austerity budget. Remarkable to have that many speakers, and to have almost all opposing the proposed cuts, instead asking for a % increase.
November 19, 2025 at 4:28 AM
Missed my number being called tonight (#609) to speak via phone to Vancouver City Council during their multi-night meeting on the city’s very controversial 0% austerity budget. Remarkable to have that many speakers, and to have almost all opposing the proposed cuts, instead asking for a % increase.
Reposted by Francis Lynn 🇨🇦
NPR: "Wholesale prices for a turkey have jumped 40% from a year ago, according to the Department of Agriculture."
Turkey sticker shock
Wholesale prices have jumped 40% from a year ago
laist.com
November 19, 2025 at 6:32 PM
NPR: "Wholesale prices for a turkey have jumped 40% from a year ago, according to the Department of Agriculture."
Reposted by Francis Lynn 🇨🇦
Apply for the 'Dr. Connie Eaves Chair in Cancer Cell Research' at UBC. Come join the dynamic research community in Vancouver 🇨🇦!
Associate Professor (tenure) or Professor (tenure) Dr. Connie Eaves Chair in Cancer Stem Cell Research
Academic Job Category Faculty Bargaining Job Title Associate Professor (tenure) or Professor (tenure) Dr. Connie Eaves Chair in Cancer Stem Cell Research Department School of Biomedical Engineering | ...
ubc.wd10.myworkdayjobs.com
November 18, 2025 at 11:52 PM
Apply for the 'Dr. Connie Eaves Chair in Cancer Cell Research' at UBC. Come join the dynamic research community in Vancouver 🇨🇦!
Reposted by Francis Lynn 🇨🇦
Canada’s research and scientific spending is declining relative to other nations, Council of Canadian Academies report says, by @ivansemeniuk.bsky.social www.theglobeandmail.com/canada/scien... via @theglobeandmail.com
Canada’s research and scientific spending is declining relative to other nations, report says
Low rate of R&D investment plays key role in productivity crisis, according to Council of Canadian Academies
www.theglobeandmail.com
November 18, 2025 at 3:47 PM
Canada’s research and scientific spending is declining relative to other nations, Council of Canadian Academies report says, by @ivansemeniuk.bsky.social www.theglobeandmail.com/canada/scien... via @theglobeandmail.com
Reposted by Francis Lynn 🇨🇦
The lens was manufactured in 1939, in wartime Germany. At this time, the "Leica Freedom Train" was in full operation - smuggling Jews out of Germany by listing them as Leitz employees and sending them abroad to work in Leica offices in Britian, France, Hong Kong, and the United States.
Behind the camera - secret life of man who saved Jews from Nazis
Honour for German Leica manufacturer who sent prewar apprentices to US.
www.theguardian.com
November 3, 2025 at 5:27 PM
The lens was manufactured in 1939, in wartime Germany. At this time, the "Leica Freedom Train" was in full operation - smuggling Jews out of Germany by listing them as Leitz employees and sending them abroad to work in Leica offices in Britian, France, Hong Kong, and the United States.
budget just passed
November 18, 2025 at 12:03 AM
budget just passed
Reposted by Francis Lynn 🇨🇦
🧵(1/12) November is Diabetes Awareness Month, and we have many works coming out from the CIRTN labs focusing on islet biology and diabetes. For the beginning of Nov 2025, we have papers from Drs Thompson, Verchere, Chen, Dhanvantari, Hill, Hoesli, Kin, Levings, Lynn, Riddell, Rutter and Wheeler.
November 17, 2025 at 11:26 PM
🧵(1/12) November is Diabetes Awareness Month, and we have many works coming out from the CIRTN labs focusing on islet biology and diabetes. For the beginning of Nov 2025, we have papers from Drs Thompson, Verchere, Chen, Dhanvantari, Hill, Hoesli, Kin, Levings, Lynn, Riddell, Rutter and Wheeler.
Reposted by Francis Lynn 🇨🇦
Many exciting opportunities for a PhD in Life Sciences in CRG, Barcelona. If you are interested in Genomics of Diabetes check out the offer for a fully funded fellowship in our lab - we will consider candidates with experimental or computational backgrounds.
Please spread the word!
Please spread the word!
Are you looking for a PhD? Join us in Barcelona! You'll dive into a community of >100 PhD students from 30 countries exploring the frontiers of biology. You can also join an online workshop on 6 November (15:00 CET) to learn how to find the right lab for you.
More info: www.crg.eu/en/content/t...
More info: www.crg.eu/en/content/t...
October 23, 2025 at 9:09 AM
Many exciting opportunities for a PhD in Life Sciences in CRG, Barcelona. If you are interested in Genomics of Diabetes check out the offer for a fully funded fellowship in our lab - we will consider candidates with experimental or computational backgrounds.
Please spread the word!
Please spread the word!
Reposted by Francis Lynn 🇨🇦
This car is now added to my list of metaphors for genomics experiments gone wrong
November 14, 2025 at 7:18 PM
This car is now added to my list of metaphors for genomics experiments gone wrong
Reposted by Francis Lynn 🇨🇦
“The prohibited activities would include joint research, co-authorship on papers, and advising a foreign graduate student or postdoctoral fellow. The language is retroactive, meaning any interactions during the previous 5 years could make a scientist ineligible for future federal funding.”
U.S. Congress considers sweeping ban on Chinese collaborations
Researchers speak out against proposal that would bar funding for U.S. scientists working with Chinese partners or training Chinese students
www.science.org
November 14, 2025 at 1:03 AM
“The prohibited activities would include joint research, co-authorship on papers, and advising a foreign graduate student or postdoctoral fellow. The language is retroactive, meaning any interactions during the previous 5 years could make a scientist ineligible for future federal funding.”
Said by someone with a 14 year old daughter, damn.
Megyn Kelly: "I know somebody very close to this case…Jeffrey Epstein, in this person's view, was not a pedophile…He was into the barely legal type, like he liked 15 year old girls…He wasn't into like 8 year olds…There's a difference between a 15 year old and a 5 year old."
November 13, 2025 at 8:54 PM
Said by someone with a 14 year old daughter, damn.
After a night of fitful sleep I again wonder why organizations cannot live by the golden rule. Still too idealistic I guess.
November 13, 2025 at 2:38 PM
After a night of fitful sleep I again wonder why organizations cannot live by the golden rule. Still too idealistic I guess.
Reposted by Francis Lynn 🇨🇦
Some more charts for the Vancouver budget, a response from Ken Sim on the future of the city’s climate department, and a decision to wear a sweater on camera which I’m frankly still on the fence about
November 13, 2025 at 3:58 AM
Some more charts for the Vancouver budget, a response from Ken Sim on the future of the city’s climate department, and a decision to wear a sweater on camera which I’m frankly still on the fence about
I remember the last peak in 1991 as I received a measles vaccine booster in high school. What are we doing this time?
Canada has a lot of work to do
Anti-vaccine disinformation from the US is a huge threat
www.reuters.com/business/hea...
Anti-vaccine disinformation from the US is a huge threat
www.reuters.com/business/hea...
November 11, 2025 at 5:21 PM
I remember the last peak in 1991 as I received a measles vaccine booster in high school. What are we doing this time?