Immunity isn’t static.

It rewires itself across your entire life.

This is what a memory T cell looks like up close.

🧬 2024 Nobel laureate David Baker has done the unthinkable — building proteins that never existed in nature.

From self-assembling nanostructures to molecular rotors, his work is turning biology into an engineering discipline.

#ProteinDesign #NobelPrize

🧠 Microglia are the brain’s living sensors — extending and retracting their fine “feet” to shape synapses, sense activity, and repair tissue.

In this clip from Forrest Collman’s EM team, a microglia (purple) reaches across a neuron (gold), revealing the brain’s hidden choreography.

Our eyes are extraordinary—but evolution shaped vision in wildly different ways.

🦅 Eagles see miles away.
🐈 Cats rule the dark.
🐙 Octopuses have no blind spot.
🦐 Mantis shrimp see colors we can’t imagine.

So many ways to see—one goal: make sense of light.

#Eyes #Life #Evolution

Light sheet microscopy reveals the ovary in 3D — not in slices, but as a living system.

💛 Oocytes (MVH)
💠 Blood vessels (CD31)
🧡 Granulosa cells (AMH)

A stunning look at how technology can map the architecture of fertility — where biology meets design.

The brain’s inhibitory neurons keep billions of signals in check — balancing excitation, refining rhythms, and preventing chaos.

This video shows just a glimpse of their incredible diversity.

🎥 Beauty in structure, elegance in control.

#Neuroscience

🧠 The cerebellum — 10% of brain volume, 50% of its neurons.'

A dense web of circuits predicting and correcting our every move, thought, and emotion.

The brain’s most precise learning machine sits quietly at its back.

Credit Greg Dunn!

#Neuroscience #Cerebellum #BrainScience

What you’re seeing is self-pollination in action 🌸

This thymeleaf speedwell (Veronica serpyllifolia) doesn’t wait for bees or wind — it transfers its own pollen to ensure survival. A quiet but powerful strategy in uncertain environments.

Watch mouse brain tumor cells in action 🧠

Actin (purple) gives them structure & movement, while mitochondria (green) supply the energy for growth.

Visualizing these systems helps scientists decode how tumors spread — and how we might disrupt them.

#BrainTumors #Neuroscience #Microscopy

🧠 In Alzheimer’s, brain activity becomes less complex.

Dr. Kay Jann’s team showed this drop in complexity links to tau buildup & cognitive declineseen in both typical & genetic AD.
Measuring complexity could help detect AD earlier & track its progression.

📽️ Video credit: Dr. Kay Jann & colleagues

🧠 The Parietal Cortex

Integrates sensory input for spatial mapping, body awareness, math & logic. Critical for navigation, perception, and coordinated action.

Damage can cause neglect or Gerstmann’s Syndrome.

Credit: Greg A Dunn

#Neuroscience #CognitiveScience #ParietalCortex

🌎 The World of Migrasomes 🌎

Migrasomes, pomegranate-like organelles formed by migrating cells, play key roles in signaling, mitochondrial quality control, and lateral transfer of mRNA/proteins.

A brand-new frontier in cell biology!

Credit: NIH & Lilian Chen

The Highest Resolution MRI EVER 🧠

The first 7T scans reveal brain microstructures in stunning detail — and next up is an 11.7T, $81M scanner. This leap will transform neuroscience, from mapping networks to tackling disease.

Credit: French CEA

#Neuroscience #MRI

What Happens During Cell Death 🦠

Under oxidative stress, the cell releases apoptotic vesicles—tiny packages carrying signals that guide immune cleanup and tissue repair.

Captured with MOSAIC lattice light sheet, this shows how even a cell’s “last act” shapes health and disease.

Credit Eric Betzi