Nicola Fattorelli
@nicola-fattorelli.bsky.social
Husband, Dad, Neuroscientist, mostly Nico.
Postdoc at Mancuso Lab | VIB, Belgium.
Microglia, CRISPR, AD & some single-cell bioinformagic 🧫🐭🔬
Postdoc at Mancuso Lab | VIB, Belgium.
Microglia, CRISPR, AD & some single-cell bioinformagic 🧫🐭🔬
Tomorrow we are running to raise funds and awareness for dementia research! 🧠 if you wish, you can make a donation here: action.stopalzheimer.be/teams/vib-ce...
This weekend, our teams @cmn-vib.bsky.social & our amazing lab are trading lab coats for running shoes! We're hitting the pavement to raise funds for Alzheimer's research — a cause close to our hearts and minds. Every step we take brings us closer to a cure. StopAlzheimer
April 12, 2025 at 10:21 AM
Tomorrow we are running to raise funds and awareness for dementia research! 🧠 if you wish, you can make a donation here: action.stopalzheimer.be/teams/vib-ce...
Your new hitchhiker's guide to microglia heterogeneity and cell states annotation! Congrats to @c9laura72.bsky.social, Alma and the whole team at @mancusorenzo.bsky.social lab 🍾
I am so excited to share our review on microglial heterogeneity @natureneuro.bsky.social! It was a fantastic effort by the lab, led by @c9laura72.bsky.social and Alma Mohebiany. We provide a critical view on the plethora of microglial cell states in health and disease. www.nature.com/articles/s41...
Microglia heterogeneity, modeling and cell-state annotation in development and neurodegeneration - Nature Neuroscience
Microglia have key roles in CNS development and neurodegeneration. Here, the authors provide an overview of microglia heterogeneity, cell-state annotation and model systems.
www.nature.com
April 7, 2025 at 8:49 PM
Your new hitchhiker's guide to microglia heterogeneity and cell states annotation! Congrats to @c9laura72.bsky.social, Alma and the whole team at @mancusorenzo.bsky.social lab 🍾
Reposted by Nicola Fattorelli
Big day for single cell and neuroscience. Trio of single cell perspective pieces discussing applications, opportunities, challenges, and validation of single cell and spatial genomics in neuroscience are out now in Nature Neuroscience. Links in thread below.👇 1/n
December 3, 2024 at 5:22 PM
Big day for single cell and neuroscience. Trio of single cell perspective pieces discussing applications, opportunities, challenges, and validation of single cell and spatial genomics in neuroscience are out now in Nature Neuroscience. Links in thread below.👇 1/n
Reposted by Nicola Fattorelli
The integrated transcriptomic cell atlas of human neural #organoids, Barbara Treutlein's lab, @fabiantheis.bsky.social @graycamplab.bsky.social @sergiuppasca.bsky.social @giorgiaquadrato.bsky.social and colleagues:
www.nature.com/articles/s41...
www.nature.com/articles/s41...
An integrated transcriptomic cell atlas of human neural organoids - Nature
A human neural organoid cell atlas integrating 36 single-cell transcriptomic datasets shows cell types and states and estimates transcriptomic similarity between primary and organoid counterparts, sho...
www.nature.com
November 21, 2024 at 6:39 AM
The integrated transcriptomic cell atlas of human neural #organoids, Barbara Treutlein's lab, @fabiantheis.bsky.social @graycamplab.bsky.social @sergiuppasca.bsky.social @giorgiaquadrato.bsky.social and colleagues:
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Nicola Fattorelli
My latest paper, deep proteomic analysis of mouse and human microglia: www.cell.com/cell-reports...
Deep proteomic analysis of microglia reveals fundamental biological differences between model systems
Lloyd et al. generated a comprehensive microglia proteome database, identifying over
11,000 proteins. Fundamental differences between ex vivo and in vitro microglia associated
with protein synthesis, ...
www.cell.com
November 13, 2024 at 9:24 AM
My latest paper, deep proteomic analysis of mouse and human microglia: www.cell.com/cell-reports...
Reposted by Nicola Fattorelli
There are lots of us missing, but so many joining so quickly
Please do share, and comment below to be added
go.bsky.app/5f2V6L6
(microglia starter pack also here by @mancusorenzo.bsky.social - bsky.app/starter-pack...)
Please do share, and comment below to be added
go.bsky.app/5f2V6L6
(microglia starter pack also here by @mancusorenzo.bsky.social - bsky.app/starter-pack...)
November 17, 2024 at 7:10 PM
There are lots of us missing, but so many joining so quickly
Please do share, and comment below to be added
go.bsky.app/5f2V6L6
(microglia starter pack also here by @mancusorenzo.bsky.social - bsky.app/starter-pack...)
Please do share, and comment below to be added
go.bsky.app/5f2V6L6
(microglia starter pack also here by @mancusorenzo.bsky.social - bsky.app/starter-pack...)
Reposted by Nicola Fattorelli
some great starter packs for the #glia, #astrocyte, #oligodendrocyte, #microglia, #neuro researcher: gliasky, astrocytesky, microglia
But if you also like interactions between celltypes, please help this starter pack get started. Maybe someone can connect all of us in a feed?
go.bsky.app/MHtJzeC
But if you also like interactions between celltypes, please help this starter pack get started. Maybe someone can connect all of us in a feed?
go.bsky.app/MHtJzeC
November 17, 2024 at 8:35 PM
some great starter packs for the #glia, #astrocyte, #oligodendrocyte, #microglia, #neuro researcher: gliasky, astrocytesky, microglia
But if you also like interactions between celltypes, please help this starter pack get started. Maybe someone can connect all of us in a feed?
go.bsky.app/MHtJzeC
But if you also like interactions between celltypes, please help this starter pack get started. Maybe someone can connect all of us in a feed?
go.bsky.app/MHtJzeC
Reposted by Nicola Fattorelli
Follow our monthly Microglia Webinar series at www.achucarro.org/es/european-...
European Microglia Webinar Series - Achucarro Basque Center for Neuroscience
European Microglia Webinar Series As from October 2023 a group of researchers of the University of Lausanne (CH) and ACHUCARRO have taken over the organization of the European Microglia webinar series...
www.achucarro.org
November 17, 2024 at 2:39 PM
Follow our monthly Microglia Webinar series at www.achucarro.org/es/european-...
Microglia community, let’s start the discussion 🧠 follow the Microglia Starter Pack and ask @mancusorenzo.bsky.social to add your colleagues as they join Bluesky 🦋
go.bsky.app/DT3Cp4A
go.bsky.app/DT3Cp4A
November 17, 2024 at 12:52 PM
Microglia community, let’s start the discussion 🧠 follow the Microglia Starter Pack and ask @mancusorenzo.bsky.social to add your colleagues as they join Bluesky 🦋
go.bsky.app/DT3Cp4A
go.bsky.app/DT3Cp4A
Reposted by Nicola Fattorelli
Hi Bluesky community 👋🏻🦋 just moved in! I’m a PhD student @ VIB (Belgium), interested in iron metabolism, membrane contact sites, ferroptosis, and cancer biology. If this sounds like something for you, take a look at our latest preprint 👉 www.researchsquare.com/article/rs-5...
November 15, 2024 at 11:24 PM
Hi Bluesky community 👋🏻🦋 just moved in! I’m a PhD student @ VIB (Belgium), interested in iron metabolism, membrane contact sites, ferroptosis, and cancer biology. If this sounds like something for you, take a look at our latest preprint 👉 www.researchsquare.com/article/rs-5...
Hi Bluesky 🦋 I’m Nico, a microglia enthusiast based in VIB, Belgium 🧠 if you are curious about the science we do, take a look at our latest work! Here we use xenotransplantation models to map the spectrum of human microglia responses to Alzheimer’s disease pathology www.nature.com/articles/s41...
Xenografted human microglia display diverse transcriptomic states in response to Alzheimer’s disease-related amyloid-β pathology - Nature Neuroscience
Human microglia transplanted in the mouse brain mount a multipronged response to amyloid-β pathology, displaying unique transcriptional states. Alzheimer’s disease risk genes are differentially regula...
www.nature.com
November 16, 2024 at 11:22 PM
Hi Bluesky 🦋 I’m Nico, a microglia enthusiast based in VIB, Belgium 🧠 if you are curious about the science we do, take a look at our latest work! Here we use xenotransplantation models to map the spectrum of human microglia responses to Alzheimer’s disease pathology www.nature.com/articles/s41...