Nathan Harmston
@nharmston.bsky.social
Lecturer - Computational biologist. Bit of a muppet. Interested in genome architecture, gene regulation and WNT signalling. Addicted to tea! All views my own
for information on how to apply - please see www.swbio.ac.uk/programme/ho...
How to apply – SWBiosciences Doctoral Training Partnership
www.swbio.ac.uk
November 4, 2025 at 3:28 PM
for information on how to apply - please see www.swbio.ac.uk/programme/ho...
knock, knock "hi georgina, could you help me to ..... " :P
May 17, 2025 at 6:19 AM
knock, knock "hi georgina, could you help me to ..... " :P
Bach1 is regulated by superenhancer that is regulated by the ATF4:p52 complex, which promotes cell cycle progression in multiple myeloma cells.
Really happy to have been involved in this study. Congrats to Yinghui and her team at NTU!
Really happy to have been involved in this study. Congrats to Yinghui and her team at NTU!
April 17, 2025 at 9:04 PM
Bach1 is regulated by superenhancer that is regulated by the ATF4:p52 complex, which promotes cell cycle progression in multiple myeloma cells.
Really happy to have been involved in this study. Congrats to Yinghui and her team at NTU!
Really happy to have been involved in this study. Congrats to Yinghui and her team at NTU!
any comments/criticisms/questions welcome!
April 8, 2025 at 6:06 AM
any comments/criticisms/questions welcome!
.... this implies that b-catenin independent signalling only plays a minor role (transcriptionally?) in Wnt-addicted PDAC and that their might be a regulatory grammar that determines whether a Wnt target gene is activated or repressed in response to pathway activation
April 8, 2025 at 6:06 AM
.... this implies that b-catenin independent signalling only plays a minor role (transcriptionally?) in Wnt-addicted PDAC and that their might be a regulatory grammar that determines whether a Wnt target gene is activated or repressed in response to pathway activation
Two key findings ....
1. In HPAF-II (RNF43 mutant pancreatic cancer) only 10% of genes are b-catenin independent
2. A subset of the Wnt-repressed genes is enriched for the NRE motif (as described Kim et al) and we subsequently test its function repressing a lncRNA and modulating AXIN2 expression
1. In HPAF-II (RNF43 mutant pancreatic cancer) only 10% of genes are b-catenin independent
2. A subset of the Wnt-repressed genes is enriched for the NRE motif (as described Kim et al) and we subsequently test its function repressing a lncRNA and modulating AXIN2 expression
April 8, 2025 at 6:04 AM
Two key findings ....
1. In HPAF-II (RNF43 mutant pancreatic cancer) only 10% of genes are b-catenin independent
2. A subset of the Wnt-repressed genes is enriched for the NRE motif (as described Kim et al) and we subsequently test its function repressing a lncRNA and modulating AXIN2 expression
1. In HPAF-II (RNF43 mutant pancreatic cancer) only 10% of genes are b-catenin independent
2. A subset of the Wnt-repressed genes is enriched for the NRE motif (as described Kim et al) and we subsequently test its function repressing a lncRNA and modulating AXIN2 expression
OA here ... www.everand.com/article/8138...
Singapore's Yale-NUS Shutdown Stirs Student Ire As College Becomes 'Mere Footnote'
With courses changed and faculty departing, students and ex-tutors lament the demise of the city state's first liberal arts college When maths and law Yale-NUS student Ryan Tan got into Singapore's fi...
www.everand.com
January 13, 2025 at 12:40 PM
OA here ... www.everand.com/article/8138...
Reposted by Nathan Harmston
for more information on applying please see - www.findaphd.com/phds/project...
Developing methods for differential mRNA secondary structure analysis at Cardiff University on FindAPhD.com
PhD Project - Developing methods for differential mRNA secondary structure analysis at Cardiff University, listed on FindAPhD.com
www.findaphd.com
November 25, 2024 at 9:57 AM
for more information on applying please see - www.findaphd.com/phds/project...
for more information on applying please see - www.findaphd.com/phds/project...
Developing methods for differential mRNA secondary structure analysis at Cardiff University on FindAPhD.com
PhD Project - Developing methods for differential mRNA secondary structure analysis at Cardiff University, listed on FindAPhD.com
www.findaphd.com
November 25, 2024 at 9:57 AM
for more information on applying please see - www.findaphd.com/phds/project...