Neuroengineering
@neuroengineering.bsky.social
Your (non-addictive) dose of neurotechnology news 🧠⚡️
Human superior temporal gyrus (STG) encodes the progression of a word as it unfolds in time. The neural activity tracks relative position within the word, regardless of its length, and resets at each new word boundary.
#neuroskyence @changlabucsf.bsky.social
#neuroskyence @changlabucsf.bsky.social
Human cortical dynamics of auditory word form encoding
We perceive continuous speech as a series of discrete words, despite the lack of clear acoustic boundaries. The superior temporal gyrus (STG) encodes …
www.sciencedirect.com
November 8, 2025 at 5:26 PM
Human superior temporal gyrus (STG) encodes the progression of a word as it unfolds in time. The neural activity tracks relative position within the word, regardless of its length, and resets at each new word boundary.
#neuroskyence @changlabucsf.bsky.social
#neuroskyence @changlabucsf.bsky.social
Towards a bidirectional visual neuroprosthesis 👁️⚡️
Spiking activity near intracortical stimulation sites proved to accurately predict the brightness and sharpness of perception. Using these signals in real time could one day optimize the individualized experience of each phosphene
#neuroskyence
Spiking activity near intracortical stimulation sites proved to accurately predict the brightness and sharpness of perception. Using these signals in real time could one day optimize the individualized experience of each phosphene
#neuroskyence
Neural correlates of phosphene perception in blind individuals: A step toward a bidirectional cortical visual prosthesis
Visual prostheses are improved by decoding neural signals to predict and control visual perceptions in blind individuals.
www.science.org
November 8, 2025 at 12:25 PM
Towards a bidirectional visual neuroprosthesis 👁️⚡️
Spiking activity near intracortical stimulation sites proved to accurately predict the brightness and sharpness of perception. Using these signals in real time could one day optimize the individualized experience of each phosphene
#neuroskyence
Spiking activity near intracortical stimulation sites proved to accurately predict the brightness and sharpness of perception. Using these signals in real time could one day optimize the individualized experience of each phosphene
#neuroskyence
Jeff Bezos increases his bet on Synchron
The company behind the stentrode just raised $200M in Series D funding, led by Double point ventures, Bezos Expeditions and ARCH ventures. The funding will be used to develop smaller stentrodes reaching multiple brain regions 🧠
#neuroskyence
The company behind the stentrode just raised $200M in Series D funding, led by Double point ventures, Bezos Expeditions and ARCH ventures. The funding will be used to develop smaller stentrodes reaching multiple brain regions 🧠
#neuroskyence
Neuralink Rival Synchron Raises $200 Million for Brain Implant
Synchron Inc. raised $200 million to advance its work building brain implants that doctors can insert through blood vessels, avoiding the costly and high-risk surgeries necessary to install devices ma...
www.bloomberg.com
November 7, 2025 at 9:07 AM
Jeff Bezos increases his bet on Synchron
The company behind the stentrode just raised $200M in Series D funding, led by Double point ventures, Bezos Expeditions and ARCH ventures. The funding will be used to develop smaller stentrodes reaching multiple brain regions 🧠
#neuroskyence
The company behind the stentrode just raised $200M in Series D funding, led by Double point ventures, Bezos Expeditions and ARCH ventures. The funding will be used to develop smaller stentrodes reaching multiple brain regions 🧠
#neuroskyence
Towards a unified “brain language”?
Brain-computer interfaces (BCIs) can restore communication for people who have lost their speech to a stroke or neurological disease. But these experimental systems, which combine sensors placed in the brain with algorithms that turn the neural signals of attempted speech into words, have so far
Researchers ‘decode’ Mandarin Chinese from neural signals
Advances in brain-computer interfaces could help millions who use tonal languages speak again after stroke or disease
www.science.org
November 6, 2025 at 9:27 AM
Towards a unified “brain language”?
Treating OCD with neurotechnology
Researchers at UCSF used iEEG to map brain circuits in severe OCD, identifying the ventral capsule as bridge between the prefrontal cortex and limbic system. Multi-area DBS implantation led to rapid symptom improvement 🧠
#neuroskyence @changlabucsf.bsky.social
Researchers at UCSF used iEEG to map brain circuits in severe OCD, identifying the ventral capsule as bridge between the prefrontal cortex and limbic system. Multi-area DBS implantation led to rapid symptom improvement 🧠
#neuroskyence @changlabucsf.bsky.social
Invasive brain mapping identifies personalized therapeutic neuromodulation targets that suppress OCD network activity - Translational Psychiatry
Translational Psychiatry - Invasive brain mapping identifies personalized therapeutic neuromodulation targets that suppress OCD network activity
www.nature.com
November 4, 2025 at 9:09 PM
Treating OCD with neurotechnology
Researchers at UCSF used iEEG to map brain circuits in severe OCD, identifying the ventral capsule as bridge between the prefrontal cortex and limbic system. Multi-area DBS implantation led to rapid symptom improvement 🧠
#neuroskyence @changlabucsf.bsky.social
Researchers at UCSF used iEEG to map brain circuits in severe OCD, identifying the ventral capsule as bridge between the prefrontal cortex and limbic system. Multi-area DBS implantation led to rapid symptom improvement 🧠
#neuroskyence @changlabucsf.bsky.social
DBS for epilepsy ?
Researchers demonstrated that stimulation of the thalamus helped reduce seizures by over 80%. Their approach showed a reduction in epileptiform discharges, in line with the nuclei's critical role in seizure termination
#neuroskyence #neuroAI #neuroscience
Researchers demonstrated that stimulation of the thalamus helped reduce seizures by over 80%. Their approach showed a reduction in epileptiform discharges, in line with the nuclei's critical role in seizure termination
#neuroskyence #neuroAI #neuroscience
Thalamocortical hodology to personalize electrical stimulation for focal epilepsy - Nature Communications
Over 50 million people worldwide suffer from epilepsy, and many patients remain resistant to medication. Here, the authors hypothesized that targeting thalamic nuclei with precise anatomical...
www.nature.com
October 28, 2025 at 7:06 AM
DBS for epilepsy ?
Researchers demonstrated that stimulation of the thalamus helped reduce seizures by over 80%. Their approach showed a reduction in epileptiform discharges, in line with the nuclei's critical role in seizure termination
#neuroskyence #neuroAI #neuroscience
Researchers demonstrated that stimulation of the thalamus helped reduce seizures by over 80%. Their approach showed a reduction in epileptiform discharges, in line with the nuclei's critical role in seizure termination
#neuroskyence #neuroAI #neuroscience
Bigtime publication on retinal prosthesis
@science.xyz implanted 38 patients with macular degeneration with the PRIMA subretinal implant. Paired with camera-equipped glasses, the system improved central vision in 80% of participants, allowing them to read again
@maxhodak.bsky.social #neuroskyence
@science.xyz implanted 38 patients with macular degeneration with the PRIMA subretinal implant. Paired with camera-equipped glasses, the system improved central vision in 80% of participants, allowing them to read again
@maxhodak.bsky.social #neuroskyence
Subretinal Photovoltaic Implant to Restore Vision in Geographic Atrophy Due to AMD | NEJM
Geographic atrophy due to age-related macular degeneration (AMD) is the leading cause of irreversible blindness and affects more than 5 million persons worldwide. No therapies to restore vision in ...
www.nejm.org
October 21, 2025 at 7:03 PM
Bigtime publication on retinal prosthesis
@science.xyz implanted 38 patients with macular degeneration with the PRIMA subretinal implant. Paired with camera-equipped glasses, the system improved central vision in 80% of participants, allowing them to read again
@maxhodak.bsky.social #neuroskyence
@science.xyz implanted 38 patients with macular degeneration with the PRIMA subretinal implant. Paired with camera-equipped glasses, the system improved central vision in 80% of participants, allowing them to read again
@maxhodak.bsky.social #neuroskyence
New paper: Working memory readout varies with frontal theta rhythms. A theta traveling wave swept across the frontal cortex like radar, modulating performance of a working memory task. Because cognition is rhythmic.
www.cell.com/neuron/abstr...
#neuroscience @picowerinstitute.bsky.social
www.cell.com/neuron/abstr...
#neuroscience @picowerinstitute.bsky.social
Working memory readout varies with frontal theta rhythms
Han et al. show that frontal theta oscillations rhythmically control access to working
memory. The theta rhythm sweeps across the mental image, shaping behavior by coordinating
spikes and beta oscilla...
www.cell.com
October 20, 2025 at 7:53 PM
🧠 In this behind-the-scenes video, Neuralink's surgery engineering team shows how they build realistic head and brain models from patient CT and MRI scans.
These "proxies" let surgeons rehearse each procedure in advance.
🎥 youtube.com/watch?v=WhG-...
These "proxies" let surgeons rehearse each procedure in advance.
🎥 youtube.com/watch?v=WhG-...
How Elon Musk’s Neuralink Builds Fake Brains
YouTube video by Core Memory
youtube.com
October 16, 2025 at 12:59 PM
🧠 In this behind-the-scenes video, Neuralink's surgery engineering team shows how they build realistic head and brain models from patient CT and MRI scans.
These "proxies" let surgeons rehearse each procedure in advance.
🎥 youtube.com/watch?v=WhG-...
These "proxies" let surgeons rehearse each procedure in advance.
🎥 youtube.com/watch?v=WhG-...
Reposted by Neuroengineering
A big push for #BCI and #neurotechnology in Europe! We implanted our second microelectrode array #BCI @tum.de. Huge thanks to our pioneer and to fantastic colleagues in #Neurosurgery and #Robotics #Machine #Intelligence 🧠🦾🧪 #neuroskyence @neuroengineering.bsky.social
www.tum.de/en/news-and-...
www.tum.de/en/news-and-...
Brain-computer interface for a patient with quadriplegia
A team at the Technical University of Munich’s TUM University Hospital has implanted a brain-computer interface in a patient paralyzed from the neck down.
www.tum.de
October 15, 2025 at 11:53 AM
A big push for #BCI and #neurotechnology in Europe! We implanted our second microelectrode array #BCI @tum.de. Huge thanks to our pioneer and to fantastic colleagues in #Neurosurgery and #Robotics #Machine #Intelligence 🧠🦾🧪 #neuroskyence @neuroengineering.bsky.social
www.tum.de/en/news-and-...
www.tum.de/en/news-and-...
Ultrasound maps deep brain function over months
Scientists used functional ultrasound imaging to record from primate parietal cortex over months. Their method combines high spatial resolution and long-term stability, revealing direction-tuned saccadic neural patches
#neuroskyence #compneurosky
Scientists used functional ultrasound imaging to record from primate parietal cortex over months. Their method combines high spatial resolution and long-term stability, revealing direction-tuned saccadic neural patches
#neuroskyence #compneurosky
Functional ultrasound neuroimaging reveals mesoscopic organization of saccades in the lateral intraparietal area - Nature Communications
The functional organization of the posterior parietal cortex (PPC) for guiding eye movements has remained unknown. Here, the authors use functional ultrasound neuroimaging to reveal small, tuned clust...
www.nature.com
October 14, 2025 at 8:03 PM
Ultrasound maps deep brain function over months
Scientists used functional ultrasound imaging to record from primate parietal cortex over months. Their method combines high spatial resolution and long-term stability, revealing direction-tuned saccadic neural patches
#neuroskyence #compneurosky
Scientists used functional ultrasound imaging to record from primate parietal cortex over months. Their method combines high spatial resolution and long-term stability, revealing direction-tuned saccadic neural patches
#neuroskyence #compneurosky
Reposted by Neuroengineering
OpenNeuro @openneuro.bsky.social just hit a huge milestone: 1500 datasets! Congrats to the team on making this project so successful over the last 7 years.
October 13, 2025 at 11:35 PM
OpenNeuro @openneuro.bsky.social just hit a huge milestone: 1500 datasets! Congrats to the team on making this project so successful over the last 7 years.
🧠⚡️ Can transcranial alternating current stimulation (tACS) truly rhythmically modulate brain activity in humans?
More than 30 labs are joining forces in the tACS Challenge, a global effort to test one of brain stimulation's biggest questions.
🧵1/5
More than 30 labs are joining forces in the tACS Challenge, a global effort to test one of brain stimulation's biggest questions.
🧵1/5
October 13, 2025 at 1:42 PM
🧠⚡️ Can transcranial alternating current stimulation (tACS) truly rhythmically modulate brain activity in humans?
More than 30 labs are joining forces in the tACS Challenge, a global effort to test one of brain stimulation's biggest questions.
🧵1/5
More than 30 labs are joining forces in the tACS Challenge, a global effort to test one of brain stimulation's biggest questions.
🧵1/5
Precision Neuroscience published their high-density ECoG in Nature Biomed. Eng.
The startup shows a 1,024-channel grid implanted through a cortical slit in pigs, and intraoperative neural recordings and stimulation in five humans at sub-mm resolution.
#neuroskyence @precisionneuro.bsky.social
The startup shows a 1,024-channel grid implanted through a cortical slit in pigs, and intraoperative neural recordings and stimulation in five humans at sub-mm resolution.
#neuroskyence @precisionneuro.bsky.social
Minimally invasive implantation of scalable high-density cortical microelectrode arrays for multimodal neural decoding and stimulation - Nature Biomedical Engineering
A 1,024-channel microelectrode array is delivered to the brain cortex via a minimally invasive incision in the skull and dura, and allows recording, stimulation and neural decoding across large portions of the brain in porcine models and human neurosurgical patients.
www.nature.com
October 4, 2025 at 9:25 PM
Precision Neuroscience published their high-density ECoG in Nature Biomed. Eng.
The startup shows a 1,024-channel grid implanted through a cortical slit in pigs, and intraoperative neural recordings and stimulation in five humans at sub-mm resolution.
#neuroskyence @precisionneuro.bsky.social
The startup shows a 1,024-channel grid implanted through a cortical slit in pigs, and intraoperative neural recordings and stimulation in five humans at sub-mm resolution.
#neuroskyence @precisionneuro.bsky.social
Can we combine neural data across individuals to improve speech BCIs?
A recent study used transfer learning on distributed iEEG recordings to enhance speech decoding. By learning shared latent manifolds, their cross-subject model outperformed individual models in a speech motor task.
#neuroskyence
A recent study used transfer learning on distributed iEEG recordings to enhance speech decoding. By learning shared latent manifolds, their cross-subject model outperformed individual models in a speech motor task.
#neuroskyence
Transfer learning via distributed brain recordings enables reliable speech decoding - Nature Communications
Speech brain-computer interfaces face challenges scaling across individuals with different brain organization. Using minimally invasive recordings from 25 patients, the authors developed transfer learning methods that enable robust speech decoding even with incomplete brain coverage.
www.nature.com
October 4, 2025 at 9:15 PM
Can we combine neural data across individuals to improve speech BCIs?
A recent study used transfer learning on distributed iEEG recordings to enhance speech decoding. By learning shared latent manifolds, their cross-subject model outperformed individual models in a speech motor task.
#neuroskyence
A recent study used transfer learning on distributed iEEG recordings to enhance speech decoding. By learning shared latent manifolds, their cross-subject model outperformed individual models in a speech motor task.
#neuroskyence
Neuropixel's newest ultra-high density probe enables larger neuronal yield (up to 2x), with over 6000 recording channels.
#neuroskyence
#neuroskyence
Neuropixels Ultra!
By @steinmetzneuro.bsky.social, who led a big collaboration
www.sciencedirect.com/science/arti...
By @steinmetzneuro.bsky.social, who led a big collaboration
www.sciencedirect.com/science/arti...
Ultra-high-density Neuropixels probes improve detection and identification in neuronal recordings
To understand the neural basis of behavior, it is essential to sensitively and accurately measure neural activity at single-neuron and single-spike re…
www.sciencedirect.com
September 30, 2025 at 6:05 PM
Neuropixel's newest ultra-high density probe enables larger neuronal yield (up to 2x), with over 6000 recording channels.
#neuroskyence
#neuroskyence
Optimizing stimulation patterns for visual implants 👁️ Check out @mbeyeler.bsky.social's recent study on using spiking activity to adapt stimulation parameters for more stable and reliable perception
#neuroskyence #bci
#neuroskyence #bci
👁️🧠 New preprint: We demonstrate the first data-driven neural control framework for a visual cortical implant in a blind human!
TL;DR Deep learning lets us synthesize efficient stimulation patterns that reliably evoke percepts, outperforming conventional calibration.
www.biorxiv.org/content/10.1...
TL;DR Deep learning lets us synthesize efficient stimulation patterns that reliably evoke percepts, outperforming conventional calibration.
www.biorxiv.org/content/10.1...
September 28, 2025 at 2:10 PM
Optimizing stimulation patterns for visual implants 👁️ Check out @mbeyeler.bsky.social's recent study on using spiking activity to adapt stimulation parameters for more stable and reliable perception
#neuroskyence #bci
#neuroskyence #bci
How does intracortical microstimulation (ICMS) affect the brain?
ICMS affects both vascular and immune responses. Higher currents increase blood-brain barrier leakage, letting substances enter surrounding tissue. Soon after, microglia activate and cluster around highly active regions
#neuroskyence
ICMS affects both vascular and immune responses. Higher currents increase blood-brain barrier leakage, letting substances enter surrounding tissue. Soon after, microglia activate and cluster around highly active regions
#neuroskyence
Intracortical Microstimulation Induces Rapid Microglia Process Convergence
Intracortical microstimulation (ICMS) has the potential to restore vision and hearing by stimulating relevant cortical regions in both animals and hum…
www.sciencedirect.com
September 26, 2025 at 6:14 AM
How does intracortical microstimulation (ICMS) affect the brain?
ICMS affects both vascular and immune responses. Higher currents increase blood-brain barrier leakage, letting substances enter surrounding tissue. Soon after, microglia activate and cluster around highly active regions
#neuroskyence
ICMS affects both vascular and immune responses. Higher currents increase blood-brain barrier leakage, letting substances enter surrounding tissue. Soon after, microglia activate and cluster around highly active regions
#neuroskyence
Better neural decoding using connectomics and emotional states? Check out @julianneumann.bsky.social newest study in Nature Biomed. Eng!
#neuroskyence #bci #compneurosky
#neuroskyence #bci #compneurosky
New paper in Nature Biomedical Engineering by @timonmerk.bsky.social !
We built a platform that unites AI-based brain signal decoding with connectomics across 123 hours of recordings from 73 patients. A step toward adaptive, network-level neurotechnology.
www.nature.com/articles/s41...
We built a platform that unites AI-based brain signal decoding with connectomics across 123 hours of recordings from 73 patients. A step toward adaptive, network-level neurotechnology.
www.nature.com/articles/s41...
Invasive neurophysiology and whole brain connectomics for neural decoding in patients with brain implants - Nature Biomedical Engineering
A modularized open-source pipeline for invasive brain signal decoding bridges the gap between closed-loop neuromodulation and clinical brain–computer interface approaches in a large patient cohort.
www.nature.com
September 26, 2025 at 6:04 AM
Better neural decoding using connectomics and emotional states? Check out @julianneumann.bsky.social newest study in Nature Biomed. Eng!
#neuroskyence #bci #compneurosky
#neuroskyence #bci #compneurosky
How does the body regulate blood pressure after SCI?
Scientists mapped the precise nerve circuits causing dangerous spikes in mice, rats, and humans. By stimulating these circuits with epidural electrical stimulation, they activated a competing pathway that stabilized blood pressure.
#neuroskyence
Scientists mapped the precise nerve circuits causing dangerous spikes in mice, rats, and humans. By stimulating these circuits with epidural electrical stimulation, they activated a competing pathway that stabilized blood pressure.
#neuroskyence
A neuronal architecture underlying autonomic dysreflexia - Nature
The neuronal architecture that develops after spinal cord injury and causes autonomic dysreflexia is uncovered.
www.nature.com
September 18, 2025 at 6:53 AM
How does the body regulate blood pressure after SCI?
Scientists mapped the precise nerve circuits causing dangerous spikes in mice, rats, and humans. By stimulating these circuits with epidural electrical stimulation, they activated a competing pathway that stabilized blood pressure.
#neuroskyence
Scientists mapped the precise nerve circuits causing dangerous spikes in mice, rats, and humans. By stimulating these circuits with epidural electrical stimulation, they activated a competing pathway that stabilized blood pressure.
#neuroskyence
Blood pressure control after SCI has been challenging — until now.
Swiss and Canadian researchers developed an implantable system that epidurally stimulates three thoracic segments, triggering a strong pressor response and rapidly reducing hypotensive symptoms.
#neuroskyence #sci #onward
Swiss and Canadian researchers developed an implantable system that epidurally stimulates three thoracic segments, triggering a strong pressor response and rapidly reducing hypotensive symptoms.
#neuroskyence #sci #onward
An implantable system to restore hemodynamic stability after spinal cord injury - Nature Medicine
A purpose-built implantable system based on biomimetic epidural electrical stimulation of the spinal cord reduces the severity of hypotensive complications in people with spinal cord injury and improv...
www.nature.com
September 18, 2025 at 6:45 AM
Blood pressure control after SCI has been challenging — until now.
Swiss and Canadian researchers developed an implantable system that epidurally stimulates three thoracic segments, triggering a strong pressor response and rapidly reducing hypotensive symptoms.
#neuroskyence #sci #onward
Swiss and Canadian researchers developed an implantable system that epidurally stimulates three thoracic segments, triggering a strong pressor response and rapidly reducing hypotensive symptoms.
#neuroskyence #sci #onward
How far can intravascular electrodes reach?
Scientists miniaturized stentrode-like electrodes to access small, deep cortical veins. Their probe goes beyond large vessels used by Synchron, enabling recordings from hand and speech regions with ECoG-level quality.
#neuroskyence #bci #synchron
Scientists miniaturized stentrode-like electrodes to access small, deep cortical veins. Their probe goes beyond large vessels used by Synchron, enabling recordings from hand and speech regions with ECoG-level quality.
#neuroskyence #bci #synchron
Microendovascular Neural Recording from Cortical and Deep Vessels with High Precision and Minimal Invasiveness
Intravascular electroencephalography (ivEEG) using micro-intravascular electrodes was developed. Cortical-vein ivEEG showed a higher signal-to-noise ratio and finer spatial resolution of somatosensor....
advanced.onlinelibrary.wiley.com
September 14, 2025 at 10:34 AM
How far can intravascular electrodes reach?
Scientists miniaturized stentrode-like electrodes to access small, deep cortical veins. Their probe goes beyond large vessels used by Synchron, enabling recordings from hand and speech regions with ECoG-level quality.
#neuroskyence #bci #synchron
Scientists miniaturized stentrode-like electrodes to access small, deep cortical veins. Their probe goes beyond large vessels used by Synchron, enabling recordings from hand and speech regions with ECoG-level quality.
#neuroskyence #bci #synchron
Might focused ultrasound one day replace DBS?
UK Scientists built a 256-panel focused ultrasound helmet that can precisely target deep brain regions. Using theta-burst TUS, they stimulated the LGN and found visual cortex activity with effects lasting up to 40 minutes.
#neuroskyence #ultrasound
UK Scientists built a 256-panel focused ultrasound helmet that can precisely target deep brain regions. Using theta-burst TUS, they stimulated the LGN and found visual cortex activity with effects lasting up to 40 minutes.
#neuroskyence #ultrasound
Ultrasound system for precise neuromodulation of human deep brain circuits - Nature Communications
Modulating deep brain structure can lead to therapies for neurological conditions. Here, the authors show a transcranial ultrasound stimulation (TUS) system featuring a 256-element helmet-shaped trans...
www.nature.com
September 14, 2025 at 10:19 AM
Might focused ultrasound one day replace DBS?
UK Scientists built a 256-panel focused ultrasound helmet that can precisely target deep brain regions. Using theta-burst TUS, they stimulated the LGN and found visual cortex activity with effects lasting up to 40 minutes.
#neuroskyence #ultrasound
UK Scientists built a 256-panel focused ultrasound helmet that can precisely target deep brain regions. Using theta-burst TUS, they stimulated the LGN and found visual cortex activity with effects lasting up to 40 minutes.
#neuroskyence #ultrasound
As we get closer to market approval for our breakthrough retinal prosthesis, it's time for a Science patient registry.
If you or a family member have late stage macular degeneration (AMD), retinitis pigmentosa, or Stargardt disease, please consider getting in touch!
science.xyz/news/science...
If you or a family member have late stage macular degeneration (AMD), retinitis pigmentosa, or Stargardt disease, please consider getting in touch!
science.xyz/news/science...
Connecting the Blind to Groundbreaking BCI Vision Restoration Technology Through Science Corporation’s Patient Registry for Retinal Diseases | Science Corporation
Science Corporation is a clinical-stage medical technology company.
science.xyz
September 11, 2025 at 9:18 PM
Full professor complaining to an assistant professor on how hard it is to get funding nowadays
September 10, 2025 at 8:24 PM