Alexey Nesvizhskii
@nesvilab.bsky.social
Godfrey D. Stobbe Professor of Bioinformatics at U of Michigan. Trained as a theoretical physicist, now focusing on proteomics and proteogenomics. https://fragpipe.nesvilab.org/
Conventional proteomics searches struggle with many modifications and fully open searches may be difficult to interpret. We introduce a "detailed" mass offset search in #MSFragger boosting interpretability and localization especially in complex cases (e.g. FPOP data): www.biorxiv.org/content/10.1...
August 1, 2025 at 9:33 PM
Conventional proteomics searches struggle with many modifications and fully open searches may be difficult to interpret. We introduce a "detailed" mass offset search in #MSFragger boosting interpretability and localization especially in complex cases (e.g. FPOP data): www.biorxiv.org/content/10.1...
Wow, a record breaking number of the Nesvizhskii lab members attending #ASMS2025! 9 posters, 3 evening workshops, and one Bioinformatics Hub on #FragPipe. Plus multiple collaborative posters with other groups. See you in Baltimore! PS. Below is our recent group photo, including all those attending
May 30, 2025 at 7:45 PM
Exciting news: We have released #FragPipe 23, and it's one of our biggest updates ever. Windows installer, support for TMT on Astral and timsTOF, TMT35, PTM site reports for DIA, improved Astral data handling in #MSFragger, improved diaTracer for diaPASEF data, better Skyline integration, and more!
May 5, 2025 at 4:06 AM
Exciting news: We have released #FragPipe 23, and it's one of our biggest updates ever. Windows installer, support for TMT on Astral and timsTOF, TMT35, PTM site reports for DIA, improved Astral data handling in #MSFragger, improved diaTracer for diaPASEF data, better Skyline integration, and more!
Are you a fan of FragPipe-Analyst? Or a member of the CPTAC Proteogenomics consortium? Then you for sure know how awesome Leo (Yi Hsiao) is! And today we celebrate him receiving the Rackham Predoctoral Fellowship award from the University of Michigan. Congratulations, Leo!
April 22, 2025 at 8:13 PM
Are you a fan of FragPipe-Analyst? Or a member of the CPTAC Proteogenomics consortium? Then you for sure know how awesome Leo (Yi Hsiao) is! And today we celebrate him receiving the Rackham Predoctoral Fellowship award from the University of Michigan. Congratulations, Leo!
This man played a part… ~25 years ago. This photo is from a few weeks ago at the Zurich zoo, where there was a social event as part of Ruedi’s celebration symposium. And, by the way, there is literally an elephant in the room, in the enclosure behind us.
March 20, 2025 at 7:56 PM
This man played a part… ~25 years ago. This photo is from a few weeks ago at the Zurich zoo, where there was a social event as part of Ruedi’s celebration symposium. And, by the way, there is literally an elephant in the room, in the enclosure behind us.
One of the most significant and challenging projects of my career so far. PepCentric: a scalable computational platform utilizing novel 2-D fragment indexing for rapid peptide-centric searches, enabling proteogenomics searches against billions of spectra in seconds. www.biorxiv.org/content/10.1...
March 4, 2025 at 9:09 AM
One of the most significant and challenging projects of my career so far. PepCentric: a scalable computational platform utilizing novel 2-D fragment indexing for rapid peptide-centric searches, enabling proteogenomics searches against billions of spectra in seconds. www.biorxiv.org/content/10.1...
Ok, my first post here, to test how it works. Blank page... writers block! Resorting to an old favorite photo. Hopefully there is an active proteomics community here (and who knows, maybe that curious squirrel joined as well?)
November 17, 2024 at 12:16 AM
Ok, my first post here, to test how it works. Blank page... writers block! Resorting to an old favorite photo. Hopefully there is an active proteomics community here (and who knows, maybe that curious squirrel joined as well?)