Martin Loose
@nartimsoole.bsky.social
Interested in protein self-organization. We rebuild the bacterial cell division machinery and small GTPase networks in vitro. https://looselab.ist.ac.at
Marko also found that "diluting" the CTL in a filament, by mixing WT FtsZ and a version without linker, drastically reduces ring diameter:
November 26, 2025 at 9:29 PM
Marko also found that "diluting" the CTL in a filament, by mixing WT FtsZ and a version without linker, drastically reduces ring diameter:
In vitro, increasing the charge segregation in the linker increased filament curvature and decreased Z-ring size! Treadmilling dynamics were unaffected.
November 26, 2025 at 9:29 PM
In vitro, increasing the charge segregation in the linker increased filament curvature and decreased Z-ring size! Treadmilling dynamics were unaffected.
We examined ~4,600 FtsZ sequences and found that charge segregation in the disordered CTL appears to correlate with cell width across species: FtsZ from wider bacteria tends to have more uniform charge distribution in the linker, whereas high charge segregation is mostly found in skinny cells.
November 26, 2025 at 9:29 PM
We examined ~4,600 FtsZ sequences and found that charge segregation in the disordered CTL appears to correlate with cell width across species: FtsZ from wider bacteria tends to have more uniform charge distribution in the linker, whereas high charge segregation is mostly found in skinny cells.
Benjamin was also able to acquire fantastic live cell movies of CorM filament dynamics:
July 2, 2025 at 11:35 AM
Benjamin was also able to acquire fantastic live cell movies of CorM filament dynamics: