NanoImaging Services
@nanoimaging.bsky.social
We are a cryoEM-focused US-based CRO (we own 3 microscopes on the West Coast, and 3 microscopes on the East Coast), and we acquired Proteos in Kalamazoo, MI, in January of this year. Contact us for cryoEM, gene-to-structure, or protein production.
🧪 Conflicting results from DLS? #CryoTEM imaging can provide quantitative and qualitative data for smaller particles, like iron nanoparticle formulations, all in one study. Reach out to nischr@nanoimagingservices.com to learn how cryo-TEM imaging can help you meet milestones faster.
September 24, 2025 at 5:08 PM
🧪 Conflicting results from DLS? #CryoTEM imaging can provide quantitative and qualitative data for smaller particles, like iron nanoparticle formulations, all in one study. Reach out to nischr@nanoimagingservices.com to learn how cryo-TEM imaging can help you meet milestones faster.
🚀 Fast track your #HPV therapeutics with #cryoTEM imaging. From initial characterization to 3D structures, we support you throughout the entire pipeline, including regulatory submissions.
🧪 Want the proof? See our published work on Gardasil®: www.nanoimagingservices.com/resources/ho...
🧪 Want the proof? See our published work on Gardasil®: www.nanoimagingservices.com/resources/ho...
September 5, 2025 at 5:04 PM
🚀 Fast track your #HPV therapeutics with #cryoTEM imaging. From initial characterization to 3D structures, we support you throughout the entire pipeline, including regulatory submissions.
🧪 Want the proof? See our published work on Gardasil®: www.nanoimagingservices.com/resources/ho...
🧪 Want the proof? See our published work on Gardasil®: www.nanoimagingservices.com/resources/ho...
🧪 Are you using cryo-EM to look at small soluble proteins? Walk through each stage from protein production to structure determination, with practical insights and lessons from a recent case study on CYP3A4 with live Q&A.
Register: nimgs.zoom.us/webinar/regi...
Register: nimgs.zoom.us/webinar/regi...
August 14, 2025 at 5:56 PM
🧪 Are you using cryo-EM to look at small soluble proteins? Walk through each stage from protein production to structure determination, with practical insights and lessons from a recent case study on CYP3A4 with live Q&A.
Register: nimgs.zoom.us/webinar/regi...
Register: nimgs.zoom.us/webinar/regi...
When it comes to #lentivirus characterization, seeing is believing. Traditional analytical methods tell you what's there, but #cryoTEM shows you exactly how it's organized.
Learn more: www.nanoimagingservices.com/nanoparticle...
Learn more: www.nanoimagingservices.com/nanoparticle...
August 6, 2025 at 4:50 PM
When it comes to #lentivirus characterization, seeing is believing. Traditional analytical methods tell you what's there, but #cryoTEM shows you exactly how it's organized.
Learn more: www.nanoimagingservices.com/nanoparticle...
Learn more: www.nanoimagingservices.com/nanoparticle...
How do you choose a nanoparticle characterization method? While there are many techniques available, cryo-TEM stands out by revealing information other methods miss.
Dive into the comparison: www.nanoimagingservices.com/about/blog/v...
Dive into the comparison: www.nanoimagingservices.com/about/blog/v...
August 5, 2025 at 6:02 PM
How do you choose a nanoparticle characterization method? While there are many techniques available, cryo-TEM stands out by revealing information other methods miss.
Dive into the comparison: www.nanoimagingservices.com/about/blog/v...
Dive into the comparison: www.nanoimagingservices.com/about/blog/v...
Ever wondered how buffers impact #cryoEM structures?
🧪 DMSO and cryoprotectants can be tolerated at low concentrations. If you're curious if your buffer will be compatible, schedule a call with our experts: www.nanoimagingservices.com/contact
🧪 DMSO and cryoprotectants can be tolerated at low concentrations. If you're curious if your buffer will be compatible, schedule a call with our experts: www.nanoimagingservices.com/contact
August 1, 2025 at 3:27 PM
Ever wondered how buffers impact #cryoEM structures?
🧪 DMSO and cryoprotectants can be tolerated at low concentrations. If you're curious if your buffer will be compatible, schedule a call with our experts: www.nanoimagingservices.com/contact
🧪 DMSO and cryoprotectants can be tolerated at low concentrations. If you're curious if your buffer will be compatible, schedule a call with our experts: www.nanoimagingservices.com/contact
Are you looking for comprehensive, reliable particle sizing analysis? From LNPs to iron nanoparticles, cryo-TEM semi-automated particle contouring and sizing provides precise particle size distribution measurement for a range of samples.
Learn more at www.nanoimagingservices.com/nanoparticle...
Learn more at www.nanoimagingservices.com/nanoparticle...
July 22, 2025 at 5:04 PM
Are you looking for comprehensive, reliable particle sizing analysis? From LNPs to iron nanoparticles, cryo-TEM semi-automated particle contouring and sizing provides precise particle size distribution measurement for a range of samples.
Learn more at www.nanoimagingservices.com/nanoparticle...
Learn more at www.nanoimagingservices.com/nanoparticle...
🧪 Ever wondered what the difference is between #cryoEM and #negativestain #TEM is? Find out in today's FAQ Friday!
July 18, 2025 at 2:47 PM
🧪 Ever wondered what the difference is between #cryoEM and #negativestain #TEM is? Find out in today's FAQ Friday!
During a recent webinar, we were asked, “How does automated cryo-TEM particle picking for AAV full/empty capsids compare to other orthogonal methods?”
Watch the webinar in full for a great explanation of cryo-TEM imaging & analysis of AAV, and more of your great questions: youtu.be/w7kRfNZX_SI
Watch the webinar in full for a great explanation of cryo-TEM imaging & analysis of AAV, and more of your great questions: youtu.be/w7kRfNZX_SI
July 7, 2025 at 6:02 PM
During a recent webinar, we were asked, “How does automated cryo-TEM particle picking for AAV full/empty capsids compare to other orthogonal methods?”
Watch the webinar in full for a great explanation of cryo-TEM imaging & analysis of AAV, and more of your great questions: youtu.be/w7kRfNZX_SI
Watch the webinar in full for a great explanation of cryo-TEM imaging & analysis of AAV, and more of your great questions: youtu.be/w7kRfNZX_SI
Poor contrast TEM images got you feeling grey? No problem!
Our latest tutorial will help you quickly & easily enhance the contrast and add scale bars to your #cryoTEM or negative stain TEM images so they’re ready for publication:
www.nanoimagingservices.com/about/blog/e...
Our latest tutorial will help you quickly & easily enhance the contrast and add scale bars to your #cryoTEM or negative stain TEM images so they’re ready for publication:
www.nanoimagingservices.com/about/blog/e...
June 25, 2025 at 6:03 PM
Poor contrast TEM images got you feeling grey? No problem!
Our latest tutorial will help you quickly & easily enhance the contrast and add scale bars to your #cryoTEM or negative stain TEM images so they’re ready for publication:
www.nanoimagingservices.com/about/blog/e...
Our latest tutorial will help you quickly & easily enhance the contrast and add scale bars to your #cryoTEM or negative stain TEM images so they’re ready for publication:
www.nanoimagingservices.com/about/blog/e...
Unexpected results in your #LNP formulations? Join our webinar + Q&A to learn how #cryoTEM imaging can help provide answers.
We will reveal how cryo-TEM can provide reliable, reproducible data (size, morphology, lamellarity, blebs) in one dataset.
Sign up: nimgs.zoom.us/webinar/regi...
We will reveal how cryo-TEM can provide reliable, reproducible data (size, morphology, lamellarity, blebs) in one dataset.
Sign up: nimgs.zoom.us/webinar/regi...
June 10, 2025 at 3:55 PM
Unexpected results in your #LNP formulations? Join our webinar + Q&A to learn how #cryoTEM imaging can help provide answers.
We will reveal how cryo-TEM can provide reliable, reproducible data (size, morphology, lamellarity, blebs) in one dataset.
Sign up: nimgs.zoom.us/webinar/regi...
We will reveal how cryo-TEM can provide reliable, reproducible data (size, morphology, lamellarity, blebs) in one dataset.
Sign up: nimgs.zoom.us/webinar/regi...
Have you signed up yet? In just 1 week, Dr. Mandy Janssen will be giving a webinar + Q&A diving into the applications of #cryoTEM for #LNP development!
Don't miss out on this deep dive: nimgs.zoom.us/webinar/regi...
Can't make it live? Sign up to get a recording, or send in your questions!
Don't miss out on this deep dive: nimgs.zoom.us/webinar/regi...
Can't make it live? Sign up to get a recording, or send in your questions!
June 5, 2025 at 2:46 PM
Have you signed up yet? In just 1 week, Dr. Mandy Janssen will be giving a webinar + Q&A diving into the applications of #cryoTEM for #LNP development!
Don't miss out on this deep dive: nimgs.zoom.us/webinar/regi...
Can't make it live? Sign up to get a recording, or send in your questions!
Don't miss out on this deep dive: nimgs.zoom.us/webinar/regi...
Can't make it live? Sign up to get a recording, or send in your questions!
FAQ Friday! Dr. Sarah Strassler Sulley touches on the differences between cryo-EM and HDX for epitop emapping.
Want more? Check out our blog with an in-depth technique comparison: www.nanoimagingservices.com/about/blog/e...
Want more? Check out our blog with an in-depth technique comparison: www.nanoimagingservices.com/about/blog/e...
May 30, 2025 at 5:04 PM
FAQ Friday! Dr. Sarah Strassler Sulley touches on the differences between cryo-EM and HDX for epitop emapping.
Want more? Check out our blog with an in-depth technique comparison: www.nanoimagingservices.com/about/blog/e...
Want more? Check out our blog with an in-depth technique comparison: www.nanoimagingservices.com/about/blog/e...
Looking for ways to enhance your #LNP analysis tools?
Dr. Mandy Janssen will present how #cryoTEM imaging & automated analysis can reveal multiple CQAs all in one dataset.
Questions? Stick around after the webinar for a Q&A with Mandy.
Sign up: nimgs.zoom.us/webinar/regi...
Dr. Mandy Janssen will present how #cryoTEM imaging & automated analysis can reveal multiple CQAs all in one dataset.
Questions? Stick around after the webinar for a Q&A with Mandy.
Sign up: nimgs.zoom.us/webinar/regi...
May 19, 2025 at 7:12 PM
Looking for ways to enhance your #LNP analysis tools?
Dr. Mandy Janssen will present how #cryoTEM imaging & automated analysis can reveal multiple CQAs all in one dataset.
Questions? Stick around after the webinar for a Q&A with Mandy.
Sign up: nimgs.zoom.us/webinar/regi...
Dr. Mandy Janssen will present how #cryoTEM imaging & automated analysis can reveal multiple CQAs all in one dataset.
Questions? Stick around after the webinar for a Q&A with Mandy.
Sign up: nimgs.zoom.us/webinar/regi...
How big are cryo-EM grids exactly? Find out!
May 16, 2025 at 5:02 PM
How big are cryo-EM grids exactly? Find out!
It's tomorrow! Join us to learn about automated cryo-TEM analysis of AAV full/empty capsid ratios.
Can't make it? Sign up anyway to receive a recording.
Don't miss this webinar + Q&A session: nimgs.zoom.us/webinar/regi...
Can't make it? Sign up anyway to receive a recording.
Don't miss this webinar + Q&A session: nimgs.zoom.us/webinar/regi...
May 14, 2025 at 5:10 PM
It's tomorrow! Join us to learn about automated cryo-TEM analysis of AAV full/empty capsid ratios.
Can't make it? Sign up anyway to receive a recording.
Don't miss this webinar + Q&A session: nimgs.zoom.us/webinar/regi...
Can't make it? Sign up anyway to receive a recording.
Don't miss this webinar + Q&A session: nimgs.zoom.us/webinar/regi...
Webinar! Enhance LNP Development: Cryo-TEM & Automated Image Analysis Tools
Enable high-resolution visualization of LNPs in near-native state, analyze multiple CQAs in 1 dataset, & use automated image analysis tools for quantitative measurements.
Register: nimgs.zoom.us/webinar/regi...
Enable high-resolution visualization of LNPs in near-native state, analyze multiple CQAs in 1 dataset, & use automated image analysis tools for quantitative measurements.
Register: nimgs.zoom.us/webinar/regi...
May 12, 2025 at 3:39 PM
Webinar! Enhance LNP Development: Cryo-TEM & Automated Image Analysis Tools
Enable high-resolution visualization of LNPs in near-native state, analyze multiple CQAs in 1 dataset, & use automated image analysis tools for quantitative measurements.
Register: nimgs.zoom.us/webinar/regi...
Enable high-resolution visualization of LNPs in near-native state, analyze multiple CQAs in 1 dataset, & use automated image analysis tools for quantitative measurements.
Register: nimgs.zoom.us/webinar/regi...
One week out! Join us for a webinar, "Automated Cryo-TEM Analysis of AAV Empty/Full Capsid Ratios".
Whether you're troubleshooting or aiming to streamline AAV manufacturing process, we'll demonstrate how cryo-TEM can drive faster informed decisions.
Sign up: nimgs.zoom.us/webinar/regi...
Whether you're troubleshooting or aiming to streamline AAV manufacturing process, we'll demonstrate how cryo-TEM can drive faster informed decisions.
Sign up: nimgs.zoom.us/webinar/regi...
May 9, 2025 at 5:56 PM
One week out! Join us for a webinar, "Automated Cryo-TEM Analysis of AAV Empty/Full Capsid Ratios".
Whether you're troubleshooting or aiming to streamline AAV manufacturing process, we'll demonstrate how cryo-TEM can drive faster informed decisions.
Sign up: nimgs.zoom.us/webinar/regi...
Whether you're troubleshooting or aiming to streamline AAV manufacturing process, we'll demonstrate how cryo-TEM can drive faster informed decisions.
Sign up: nimgs.zoom.us/webinar/regi...
What are sample size requirements for Single Particle Analysis cryo-EM? Join Dr. Sarah Strassler Sulley to find out!
Questions about cryo-EM? Let us know!
Questions about cryo-EM? Let us know!
April 18, 2025 at 5:02 PM
What are sample size requirements for Single Particle Analysis cryo-EM? Join Dr. Sarah Strassler Sulley to find out!
Questions about cryo-EM? Let us know!
Questions about cryo-EM? Let us know!
Did you know cryo-TEM is the only technique that can visualize blebbing on LNPs?
Check out our latest blog for detailed examples of blebs & bilayers, and a literature review: bit.ly/42oxkWH
Email us at nischr@nanoimagingservices.com to get started imaging your lipid nanoparticles!
Check out our latest blog for detailed examples of blebs & bilayers, and a literature review: bit.ly/42oxkWH
Email us at nischr@nanoimagingservices.com to get started imaging your lipid nanoparticles!
April 8, 2025 at 5:54 PM
Did you know cryo-TEM is the only technique that can visualize blebbing on LNPs?
Check out our latest blog for detailed examples of blebs & bilayers, and a literature review: bit.ly/42oxkWH
Email us at nischr@nanoimagingservices.com to get started imaging your lipid nanoparticles!
Check out our latest blog for detailed examples of blebs & bilayers, and a literature review: bit.ly/42oxkWH
Email us at nischr@nanoimagingservices.com to get started imaging your lipid nanoparticles!
It’s FAQ Friday! A well characterized sample can make all the difference for cryo-EM structure determination.
What characterization techniques do we recommend? Check in with Dr. Sarah Strassler Sulley to find out!
What else do you want to know about cryo-EM? Let us know.
What characterization techniques do we recommend? Check in with Dr. Sarah Strassler Sulley to find out!
What else do you want to know about cryo-EM? Let us know.
April 4, 2025 at 5:05 PM
It’s FAQ Friday! A well characterized sample can make all the difference for cryo-EM structure determination.
What characterization techniques do we recommend? Check in with Dr. Sarah Strassler Sulley to find out!
What else do you want to know about cryo-EM? Let us know.
What characterization techniques do we recommend? Check in with Dr. Sarah Strassler Sulley to find out!
What else do you want to know about cryo-EM? Let us know.
FAQ Friday! Have you ever wondered about the difference between Krios & Glacios microscopes? Find out now!
What #cryoEM questions do you have?
What #cryoEM questions do you have?
March 28, 2025 at 3:55 PM
FAQ Friday! Have you ever wondered about the difference between Krios & Glacios microscopes? Find out now!
What #cryoEM questions do you have?
What #cryoEM questions do you have?
Blebs on LNPs are mysterious & strange. Where do they come from? What impact do they have?
Scientist Brent Wood explores blebs & other morphological features of LNPs that can only be visualized with cryo-TEM.
Check out the images & literature review: www.nanoimagingservices.com/about/blog/t...
Scientist Brent Wood explores blebs & other morphological features of LNPs that can only be visualized with cryo-TEM.
Check out the images & literature review: www.nanoimagingservices.com/about/blog/t...
March 27, 2025 at 4:27 PM
Blebs on LNPs are mysterious & strange. Where do they come from? What impact do they have?
Scientist Brent Wood explores blebs & other morphological features of LNPs that can only be visualized with cryo-TEM.
Check out the images & literature review: www.nanoimagingservices.com/about/blog/t...
Scientist Brent Wood explores blebs & other morphological features of LNPs that can only be visualized with cryo-TEM.
Check out the images & literature review: www.nanoimagingservices.com/about/blog/t...
Seeing unexpected results in your gene & drug delivery vehicles? Cryo-TEM imaging & analysis can help.
Automated, quantitative payload encapsulation analysis can accelerate your therapeutic pipeline and help inform efficacy and safety.
www.nanoimagingservices.com/nanoparticle...
Automated, quantitative payload encapsulation analysis can accelerate your therapeutic pipeline and help inform efficacy and safety.
www.nanoimagingservices.com/nanoparticle...
March 19, 2025 at 5:19 PM
Seeing unexpected results in your gene & drug delivery vehicles? Cryo-TEM imaging & analysis can help.
Automated, quantitative payload encapsulation analysis can accelerate your therapeutic pipeline and help inform efficacy and safety.
www.nanoimagingservices.com/nanoparticle...
Automated, quantitative payload encapsulation analysis can accelerate your therapeutic pipeline and help inform efficacy and safety.
www.nanoimagingservices.com/nanoparticle...
Cryo Electron Tomography can reveal the 3D structures of heterogeneous nanoparticles, such as liposomes, LNPs, exosomes, extracellular vesicles.
3D volumes can provide a complete picture of morphology, surface decorations, & internal composition.
Learn more: bit.ly/cryo-et
3D volumes can provide a complete picture of morphology, surface decorations, & internal composition.
Learn more: bit.ly/cryo-et
March 13, 2025 at 2:42 PM
Cryo Electron Tomography can reveal the 3D structures of heterogeneous nanoparticles, such as liposomes, LNPs, exosomes, extracellular vesicles.
3D volumes can provide a complete picture of morphology, surface decorations, & internal composition.
Learn more: bit.ly/cryo-et
3D volumes can provide a complete picture of morphology, surface decorations, & internal composition.
Learn more: bit.ly/cryo-et