Marcel Schilling
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mschilli.com
Marcel Schilling
@mschilli.com
I am a Bioinformatician whose research focusses on post-transcriptional regulation in the context of Alzheimer's Disease.

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https://mschilli.com
Reposted by Marcel Schilling
🔊 We are excited to announce a new Associate Professor (Prof.Agregada) at @geneticsub.bsky.social @biologiaub.bsky.social!
👏 Congrats to Dr. Cristina González on her new position!
🧬 Her group aims to understand the metabolic modulation of early regeneration events using planarians as a model system.
November 27, 2025 at 10:21 AM
Reposted by Marcel Schilling
#OpenCloning is a an Open Source alternative to SnapGene/Benchling that supports automation and integration with other software

✅ Free
🔓 Open Source
🧬 More cloning methods than SnapGene
🤖 Can be automated with python
👨‍🔬 Built by a researcher — for researchers!

👉 Check it out at opencloning.org
November 24, 2025 at 4:57 PM
Reposted by Marcel Schilling
Interested in measuring RNAPII elongation rates? We developed DRB/TTchem-seq2 to directly measure rates across 3,000+ genes 🧬
genome.cshlp.org/content/earl...
This fantastic work led by Haiyue Liu reveals gene and intra-genic variation, links to histone marks & elongation factors
Details below! 👇
Kinetic measurement of gene-specific RNA polymerase II transcription elongation rates
An international, peer-reviewed genome sciences journal featuring outstanding original research that offers novel insights into the biology of all organisms
genome.cshlp.org
October 24, 2025 at 10:25 AM
Reposted by Marcel Schilling
I’m really happy to present #SCALPEL, a new #Nextflow tool to quantify transcript isoforms at the single-cell level using conventional 3’ scRNA-seq data #scRNA-seq #single-cell #tools #isoforms
www.nature.com/articles/s41...
Quantification of transcript isoforms at the single-cell level using SCALPEL - Nature Communications
Single-cell RNA-seq facilitates the study of transcriptome diversity in individual cells. Here, authors introduce a tool for isoform quantification at the single-cell level using 3’ scRNA-seq data, co...
www.nature.com
July 14, 2025 at 10:31 AM
Reposted by Marcel Schilling
🚨We are looking for post-doctoral candidates to apply for a MSCA fellowship.

Projects on gene regulation in neural development or neurdegenerative diseases using single-cell omics.

Computational & wet-lab candidates are welcomed! #postdoc #MSCA #Barcelona #singlecell.
Postdoctoral Fellowships
The information provided on this page is a summary of the main rules and requirements for Postdoctoral Fellowships (PFs) and who can apply for them.
marie-sklodowska-curie-actions.ec.europa.eu
June 25, 2025 at 8:23 AM
Reposted by Marcel Schilling
🚨 We’re recruiting PhD students! 🚨

Join the Stem Cell Biology and Evolution lab at @lsiexeter.bsky.social to study planarians, stem cells & evolution.

2 projects available - 1 week left to apply!
Interested and no PhD yet? Apply now. Or help us spread the word! 🙌

www.exeter.ac.uk/research/ins...
LSI PhD programme | Living Systems Institute | University of Exeter
www.exeter.ac.uk
June 1, 2025 at 5:02 PM
Reposted by Marcel Schilling
Franz Arnold Ake from @idibell.bsky.social presented SCALPEL, a Nextflow-based pipeline to quantify and characterize isoforms at single-cell resolution. Fascinating work that will be applied to study alternative polyadenylation during neural differentiation and neurodegenerative diseases.🧠
May 15, 2025 at 5:02 PM
Reposted by Marcel Schilling
It’s so nice to see this work finally out! It developed so much since its early days. The idea of long lived RNA as experience decoys is huge. Still a lot of work to be done but this is a great first step forward. Happy to have been part of it!
April 10, 2025 at 11:41 PM
Reposted by Marcel Schilling
Huge effort from @anaconesa.bsky.social at @scb.iec.cat comparing long-read RNA technologies @pacbio.bsky.social @nanoporetech.com and softwares #sqanti3, #bambu, #talon, #isoquant, for isoform discovery, still challenging to disentangle real biology from artefacts
December 13, 2024 at 12:50 PM
Reposted by Marcel Schilling
for closing the day at the #XIIJornadesBioinformàticaiGenòmica from @scb.iec.cat we have Akshay presenting a poster about STAU2 function in neurogenesis.
December 12, 2024 at 6:32 PM
Reposted by Marcel Schilling
Thrilled to have shared my mayfly research from @isabelalmudi.bsky.social lab at the #XIIJornadadeBioinformàticaiGenòmica in Lleida, organised by @scb.iec.cat. An inspiring day of brilliant talks and meaningful discussions! #EvoDevo #Bioinformatics #scRNAseq
December 12, 2024 at 5:17 PM
Reposted by Marcel Schilling
Spreading our work at the XII Jornades de Bioinformàtica i Genòmica de la @scb.iec.cat @tmontsay.bsky.social about our recent discovery rdcu.be/d04Gz of pervasive presence of not completly lysed cells in reference cell atlases @humancellatlas.org compromising quality & model training
December 12, 2024 at 10:32 AM
Reposted by Marcel Schilling
and now a talk by Franz Ake presenting SCALPEL, a pipeline for isoform quantification in single-cell data. #XIIJornadesBioinformàticaiGenòmica from @scb.iec.cat . #Nextflow #single-cell
December 12, 2024 at 11:38 AM
Reposted by Marcel Schilling
Brilliant presentation by @jamesasharpe.bsky.social at XII Jornades de Bioinformàtica i Genòmica by @scb.iec.cat about mechanistic dynamical models and #Turing patterns to go from genes to phenotypes
December 12, 2024 at 9:44 AM
Reposted by Marcel Schilling
first time scr4eam goes public! realistic & isoform-aware simulator of single-cell reads. short talk from @mschilli87.bsky.social at the #XIIJornadesBioinformaàticaiGenòmica #benchmarktools #scrna-seq
December 12, 2024 at 10:03 AM