MRC Cognition and Brain Sciences Unit, University of Cambridge
@mrccbu.bsky.social
Why do some people lose memory faster with age? A mega-analysis of 13 longitudinal datasets (3,700+ adults, 10,000+ MRIs) shows that memory decline tracks brain atrophy, especially in the hippocampus, and that these links strengthen with age, but not APOE status: www.nature.com/articles/s41...
November 27, 2025 at 9:37 AM
Why do some people lose memory faster with age? A mega-analysis of 13 longitudinal datasets (3,700+ adults, 10,000+ MRIs) shows that memory decline tracks brain atrophy, especially in the hippocampus, and that these links strengthen with age, but not APOE status: www.nature.com/articles/s41...
Researchers from MRC Cognition and Brain Sciences Unit, University of Cambridge and University of Cambridge showed that the brain stays in the adolescent phase until our early thirties. Find out more in the BBC article 👉 https://www.bbc.co.uk/news/articles/cgl6klez226o
November 25, 2025 at 3:50 PM
Researchers from MRC Cognition and Brain Sciences Unit, University of Cambridge and University of Cambridge showed that the brain stays in the adolescent phase until our early thirties. Find out more in the BBC article 👉 https://www.bbc.co.uk/news/articles/cgl6klez226o
We introduces Nonlinear TL-MDPC, a neural-network-based method to capture multidimensional, time-lagged brain connectivity in EEG/MEG data. While it outperforms linear methods in simulations, it only shows subtle gains in real data: https://doi.org/10.3389/fnhum.2025.1533034
November 19, 2025 at 10:01 AM
We introduces Nonlinear TL-MDPC, a neural-network-based method to capture multidimensional, time-lagged brain connectivity in EEG/MEG data. While it outperforms linear methods in simulations, it only shows subtle gains in real data: https://doi.org/10.3389/fnhum.2025.1533034
Happy LGBTQ+STEM Day! To mark the occasion, LGBTQ+ and ally scientists alike introduced our new pride flag to the @mrccbu.bsky.social
November 18, 2025 at 4:26 PM
Happy LGBTQ+STEM Day! To mark the occasion, LGBTQ+ and ally scientists alike introduced our new pride flag to the @mrccbu.bsky.social
We are excited to announce #COGNESTIC 2026 @mrccbu.bsky.social in Cambridge, between 14-25 Sep 2026. Our 2-week summer school provides training in state-of-the-art methods for open neuroimaging analysis and great opportunities for professional networking:
www.mrc-cbu.cam.ac.uk/events/cogne...
www.mrc-cbu.cam.ac.uk/events/cogne...
November 17, 2025 at 10:18 AM
We are excited to announce #COGNESTIC 2026 @mrccbu.bsky.social in Cambridge, between 14-25 Sep 2026. Our 2-week summer school provides training in state-of-the-art methods for open neuroimaging analysis and great opportunities for professional networking:
www.mrc-cbu.cam.ac.uk/events/cogne...
www.mrc-cbu.cam.ac.uk/events/cogne...
New research by Henderson and colleagues found graded distinctions among typical amnestic and atypical (language, visual) Alzheimer’s phenotypes. The findings support a transdiagnostic, multidimensional model of AD that spans all subtypes: https://doi.org/10.1186/s13195-025-01873-w
November 10, 2025 at 12:41 PM
New research by Henderson and colleagues found graded distinctions among typical amnestic and atypical (language, visual) Alzheimer’s phenotypes. The findings support a transdiagnostic, multidimensional model of AD that spans all subtypes: https://doi.org/10.1186/s13195-025-01873-w
People with poorer glucose control show faster learning from rewards, in turn linked to higher depression symptoms. This suggests a neurocognitive bridge between metabolic disease and mood: https://doi.org/10.1016/j.bpsgos.2025.100645
#MetabolicPsychiatry #Interoception #Depression
#MetabolicPsychiatry #Interoception #Depression
November 7, 2025 at 9:50 AM
People with poorer glucose control show faster learning from rewards, in turn linked to higher depression symptoms. This suggests a neurocognitive bridge between metabolic disease and mood: https://doi.org/10.1016/j.bpsgos.2025.100645
#MetabolicPsychiatry #Interoception #Depression
#MetabolicPsychiatry #Interoception #Depression
This article compares two key metrics with predictive power for neural health in cochlear-implant patients as well as an exploratory measure. All three measures identify simulated neural dead regions, but PECAP is best at isolating neural and non-neural factors: https://doi.org/10.1121/10.0038746
October 29, 2025 at 1:01 PM
This article compares two key metrics with predictive power for neural health in cochlear-implant patients as well as an exploratory measure. All three measures identify simulated neural dead regions, but PECAP is best at isolating neural and non-neural factors: https://doi.org/10.1121/10.0038746
We are deeply saddened by the unexpected passing of Professor Friedemann Pulvermüller, former Programme Leader at the CBU. We will remember his scientific legacy, dry humour and jazz drumming skills. Our thoughts are now with his wife Bettina and son Johannes.
October 29, 2025 at 11:32 AM
We are deeply saddened by the unexpected passing of Professor Friedemann Pulvermüller, former Programme Leader at the CBU. We will remember his scientific legacy, dry humour and jazz drumming skills. Our thoughts are now with his wife Bettina and son Johannes.
What does it mean to be both animal and thinker? Join @moatazassem.bsky.social and John Duncan on 25 November at Murray Edwards College for the launch of John’s new book ‘The Animal and the Thinker.’ Get your tickets here: www.eventbrite.co.uk/e/the-animal...
October 22, 2025 at 10:04 AM
What does it mean to be both animal and thinker? Join @moatazassem.bsky.social and John Duncan on 25 November at Murray Edwards College for the launch of John’s new book ‘The Animal and the Thinker.’ Get your tickets here: www.eventbrite.co.uk/e/the-animal...
New paper - Sex differences in healthy brain aging are unlikely to explain higher Alzheimer’s Disease prevalence in women: https://doi.org/10.1073/pnas.2510486122
October 14, 2025 at 9:00 AM
New paper - Sex differences in healthy brain aging are unlikely to explain higher Alzheimer’s Disease prevalence in women: https://doi.org/10.1073/pnas.2510486122
New paper: Mapping the task-general and task-specific neural correlates of speech production: meta-analysis and fMRI direct comparisons of category fluency and picture naming: doi.org/10.1162/IMAG...
October 6, 2025 at 9:12 AM
New paper: Mapping the task-general and task-specific neural correlates of speech production: meta-analysis and fMRI direct comparisons of category fluency and picture naming: doi.org/10.1162/IMAG...
It was hard to say goodbye after two intense and exciting weeks at COGNESTIC 2025. Thank you to all our attendees for making it such a fantastic event. From fMRI to football, EEG/MEG to electric golf, we enjoyed every moment of science, ideas, networking, and fun — even the sun joined in.
September 30, 2025 at 12:09 PM
It was hard to say goodbye after two intense and exciting weeks at COGNESTIC 2025. Thank you to all our attendees for making it such a fantastic event. From fMRI to football, EEG/MEG to electric golf, we enjoyed every moment of science, ideas, networking, and fun — even the sun joined in.
Many mental health conditions are associated with increased metabolic morbidity and mortality–why? We propose a model of interoceptive allostasis explaining how mental-metabolic comorbidity can occur and propagate through a vicious cycle of energy dysregulation: www.science.org/doi/10.1126/...
September 25, 2025 at 8:48 AM
Many mental health conditions are associated with increased metabolic morbidity and mortality–why? We propose a model of interoceptive allostasis explaining how mental-metabolic comorbidity can occur and propagate through a vicious cycle of energy dysregulation: www.science.org/doi/10.1126/...
New paper: DECRYPT trial (onlinelibrary.wiley.com/doi/epdf/10....) for youth (8-17) with PTSD following multiple traumas. Cognitive Therapy was superior to treatment-as-usual at 11-month follow-up & improved anxiety/depression.
September 15, 2025 at 12:34 PM
New paper: DECRYPT trial (onlinelibrary.wiley.com/doi/epdf/10....) for youth (8-17) with PTSD following multiple traumas. Cognitive Therapy was superior to treatment-as-usual at 11-month follow-up & improved anxiety/depression.
Does what you eat really shape your brain, and mental health? Or is it the other way around? Come discover how metabolism links body, brain, and mood with @camillanord.bsky.social at the Arches London Bridge for a SeedTalk on 30 September www.eventbrite.co.uk/e/metabolism...
September 15, 2025 at 9:46 AM
Does what you eat really shape your brain, and mental health? Or is it the other way around? Come discover how metabolism links body, brain, and mood with @camillanord.bsky.social at the Arches London Bridge for a SeedTalk on 30 September www.eventbrite.co.uk/e/metabolism...
New fMRI study shows the hippocampus signals mismatches only when our expectations are based on episodic memories — not general knowledge. Challenges theories of the hippocampus as a domain-general comparator. We also explore how brain networks respond to surprise: doi.org/10.1101/2025...
September 1, 2025 at 9:58 AM
New fMRI study shows the hippocampus signals mismatches only when our expectations are based on episodic memories — not general knowledge. Challenges theories of the hippocampus as a domain-general comparator. We also explore how brain networks respond to surprise: doi.org/10.1101/2025...
New CamCAN paper led by @noham-wolpe.bsky.social shows that older adults’ tendency to see facial expressions as more positive may not be the adaptive “rose-coloured glasses” we thought, but could signal early cognitive decline and neurodegeneration: pubmed.ncbi.nlm.nih.gov/40854689/
August 27, 2025 at 3:13 PM
New CamCAN paper led by @noham-wolpe.bsky.social shows that older adults’ tendency to see facial expressions as more positive may not be the adaptive “rose-coloured glasses” we thought, but could signal early cognitive decline and neurodegeneration: pubmed.ncbi.nlm.nih.gov/40854689/
New study from Cam-CAN using 11 different white matter (WM) measures shows WM health is multidimensional—4 latent MRI-derived factors explain 89% of WM variance, linking brain microstructure to vascular health & cognition: doi.org/10.1038/s415...
August 11, 2025 at 8:46 AM
New study from Cam-CAN using 11 different white matter (WM) measures shows WM health is multidimensional—4 latent MRI-derived factors explain 89% of WM variance, linking brain microstructure to vascular health & cognition: doi.org/10.1038/s415...
In this paper, we measured three neural responses (eCAP, eABR, eASSR) to stimulation with #cochlearimplant using the same stimulus to disentangle the effects of response type and of stimulus type on neural response properties: doi.org/10.1016/j.he...
July 31, 2025 at 8:28 AM
In this paper, we measured three neural responses (eCAP, eABR, eASSR) to stimulation with #cochlearimplant using the same stimulus to disentangle the effects of response type and of stimulus type on neural response properties: doi.org/10.1016/j.he...
International study shows that higher levels of education do not reduce rates of cognitive and brain decline in later years, contrary to views that education protects against such decline: www.nature.com/articles/s41...
@rhens.bsky.social
@rhens.bsky.social
July 28, 2025 at 10:48 AM
International study shows that higher levels of education do not reduce rates of cognitive and brain decline in later years, contrary to views that education protects against such decline: www.nature.com/articles/s41...
@rhens.bsky.social
@rhens.bsky.social
Recent research from CamCAN shows that, when pulse pressure, the difference between systolic and diastolic blood pressure, gets too high, it can damage the brain’s “wiring” (white matter), making it harder to think fast and solve puzzles: doi.org/10.1161/HYPE...
@camcan-2010.bsky.social
@camcan-2010.bsky.social
July 21, 2025 at 10:13 AM
Recent research from CamCAN shows that, when pulse pressure, the difference between systolic and diastolic blood pressure, gets too high, it can damage the brain’s “wiring” (white matter), making it harder to think fast and solve puzzles: doi.org/10.1161/HYPE...
@camcan-2010.bsky.social
@camcan-2010.bsky.social
An internation consortium explore self- vs carer-reports of apathy and motivation disorders in 335 patients with neurodegenerative disorders: doi.org/10.1093/brai...
July 15, 2025 at 8:34 AM
An internation consortium explore self- vs carer-reports of apathy and motivation disorders in 335 patients with neurodegenerative disorders: doi.org/10.1093/brai...
In a new popular science book, The Animal and the Thinker, John Duncan explains how the balance of instinct and reason answers big human questions. Right and wrong. Ambition and fulfilment. Women and men. Law and democracy. A psychologist’s perspective on “the meaning of life”
July 10, 2025 at 8:22 AM
In a new popular science book, The Animal and the Thinker, John Duncan explains how the balance of instinct and reason answers big human questions. Right and wrong. Ambition and fulfilment. Women and men. Law and democracy. A psychologist’s perspective on “the meaning of life”
Researchers present a scalable theory-free framework to describe the maths of neural processing: doi.org/10.1016/j.ne...
July 10, 2025 at 7:31 AM
Researchers present a scalable theory-free framework to describe the maths of neural processing: doi.org/10.1016/j.ne...