Michael Meers
@mpmeers.bsky.social
Assistant Prof @WashUGenetics, chromatin-mediated regulation of development. Former postdoc @fredhutch, former grad student @UNC_Biology. Views my own.
Given this is a Director's award, I'd be remiss to ignore the broader context of what the current NIH Director is presiding over right now at the NIH. These were my full thoughts when asked for a quote for this piece on what this means to me and our lab.
October 10, 2025 at 6:15 PM
Given this is a Director's award, I'd be remiss to ignore the broader context of what the current NIH Director is presiding over right now at the NIH. These were my full thoughts when asked for a quote for this piece on what this means to me and our lab.
While you're at it, check out this nice new preprint from Dave's lab that makes use of Plate-CUT&Tag data to characterize chromatin states at intermediately 5mC-methylated regions that play key roles in AML: www.biorxiv.org/content/10.1... 4/3
Intermediately Methylated Regions in Normal Cells Are Epimutation Hotspots in Cancer
DNA methylation is altered in all cancers, but the mechanisms responsible for these changes are not well understood. Using data from 100 primary samples, we show that regions with intermediate methyla...
www.biorxiv.org
September 22, 2025 at 4:42 PM
While you're at it, check out this nice new preprint from Dave's lab that makes use of Plate-CUT&Tag data to characterize chromatin states at intermediately 5mC-methylated regions that play key roles in AML: www.biorxiv.org/content/10.1... 4/3
This work was spearheaded by Brittany Johnson, the very first Meers Lab member who has now moved on to a PhD at @ibisatnu.bsky.social, with big assists from Gabe Boyle and @sarthylab.bsky.social at Seattle Children's and David Spencer here at WashU. Hoping this is the first of many for the lab! 3/3
September 22, 2025 at 4:38 PM
This work was spearheaded by Brittany Johnson, the very first Meers Lab member who has now moved on to a PhD at @ibisatnu.bsky.social, with big assists from Gabe Boyle and @sarthylab.bsky.social at Seattle Children's and David Spencer here at WashU. Hoping this is the first of many for the lab! 3/3
Inspired by Derek Janssens' work on AutoCUT&RUN/Tag that streamlined those methods for highly parallel sample processing on a liquid handling robot, we simplified that a bit by allowing any user to process 96 samples at once without any specialized equipment, with a nice use case for AML 2/3
September 22, 2025 at 4:38 PM
Inspired by Derek Janssens' work on AutoCUT&RUN/Tag that streamlined those methods for highly parallel sample processing on a liquid handling robot, we simplified that a bit by allowing any user to process 96 samples at once without any specialized equipment, with a nice use case for AML 2/3
This is fantastic stuff Evgeny! Great to see it come together so nicely. Congratulations!
June 24, 2025 at 12:43 AM
This is fantastic stuff Evgeny! Great to see it come together so nicely. Congratulations!