Pellegrini Lab
@mpellegresearch.bsky.social
A Structural Biology, Biochemistry and Biophysics lab
at Dartmouth College: we focus on rational drug design and development.
at Dartmouth College: we focus on rational drug design and development.
cell-188-6.elsevierdigitaledition.com/main/1457/in...
Commentary
Safeguarding the future of biomedical science
in the United States
Tom Maniatis
chng.it/kK2HMP5pGk
Commentary
Safeguarding the future of biomedical science
in the United States
Tom Maniatis
chng.it/kK2HMP5pGk
CELL Vol. 188 No. 6
cell-188-6.elsevierdigitaledition.com
March 21, 2025 at 4:48 PM
cell-188-6.elsevierdigitaledition.com/main/1457/in...
Commentary
Safeguarding the future of biomedical science
in the United States
Tom Maniatis
chng.it/kK2HMP5pGk
Commentary
Safeguarding the future of biomedical science
in the United States
Tom Maniatis
chng.it/kK2HMP5pGk
Here is the link for free access to our newest work on making NEMO an accessible drug target, valid for 50 days (thanks @cellpress.bsky.social ):
"The structure of a NEMO construct engineered for screening reveals novel determinants of inhibition"
authors.elsevier.com/a/1kYkD3SNvc...
"The structure of a NEMO construct engineered for screening reveals novel determinants of inhibition"
authors.elsevier.com/a/1kYkD3SNvc...
authors.elsevier.com
February 4, 2025 at 4:23 PM
Here is the link for free access to our newest work on making NEMO an accessible drug target, valid for 50 days (thanks @cellpress.bsky.social ):
"The structure of a NEMO construct engineered for screening reveals novel determinants of inhibition"
authors.elsevier.com/a/1kYkD3SNvc...
"The structure of a NEMO construct engineered for screening reveals novel determinants of inhibition"
authors.elsevier.com/a/1kYkD3SNvc...
The structure of a NEMO construct engineered for screening reveals novel determinants of inhibition: Structure www.cell.com/structure/fu...
The structure of a NEMO construct engineered for screening reveals novel determinants of inhibition
Kennedy at al. utilized protein engineering to stabilize a native-like, bioactive
coiled-coil conformation of NEMO, zipNEMO. The authors determined the crystal structure
of zipNEMO and showed that zip...
www.cell.com
February 4, 2025 at 4:11 PM
The structure of a NEMO construct engineered for screening reveals novel determinants of inhibition: Structure www.cell.com/structure/fu...