We then solved the crystal structure of AVRcap1b in complex with the NbTOL9a ENTH domain (in green). Having the interaction interface was nice, but what was really cool was that AVRcap1b was completely different to other RXLR-LWY effectors! It exhibits a novel L-shaped structure.

Thrilled to share our latest preprint! This work started during my PhD and was finished together with @jmadhuprakash.bsky.social. We found a Phytophthora infestans L-shaped effector that bridges a host TOL protein to activated NLRs to suppress immunity!
www.biorxiv.org/content/10.1...
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