Ale Mongera
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mongeralab.bsky.social
Ale Mongera
@mongeralab.bsky.social
Developmental biologist at UCL
Multicellular Morphogenesis Lab
http://zebrafishucl.org/mongera-lab
Pinned
📣Our project, “Mechanometabolic Control of Vertebrate Limb Elongation,” has been funded by Wellcome!
Over the next 8 years, we’ll collaborate with @manningresearch.bsky.social and Nathalie Agar’s group to understand the mechanics of ECM-rich mesenchymal tissues! Funded positions available!🎉
Reposted by Ale Mongera
How can we organize current theoretical approaches for developmental biology - from information to dynamical systems & GRNs - into a common framework?

We propose to think along Marr's 3 levels: computational problem, algorithm, implementation

Check out our review:
arxiv.org/abs/2510.24536
November 10, 2025 at 6:46 AM
Reposted by Ale Mongera
We are looking for: PhD Student (starting as Research Assistant) and Postdoctoral Researcher in Stem Cell Biology and Mechanobiology. Please RT💕
🔗 About our lab: renew.science/principal_in...
🎓 PhD position: jobportal.ku.dk/phd/?show=15...
🧪 Postdoc position: jobportal.ku.dk/videnskabeli...
November 3, 2025 at 7:05 PM
Reposted by Ale Mongera
🚨 Come join us @sheffielduni.bsky.social for a PhD on the evolution and development of feathers and flight! 🐣🔬

This project is supervised by @matt-towers.bsky.social & @alexgfletcher.bsky.social, and I'm excited to be involved as a project advisor. Please share!

www.findaphd.com/phds/project... 🧪
November 3, 2025 at 2:46 PM
Reposted by Ale Mongera
Had the pleasure of working with @mohannad-dardiry.bsky.social to rethink what it means to develop for life. Many thanks to @dev-journal.bsky.social! @embl.org #LifelongDevSI
October 31, 2025 at 11:24 AM
Reposted by Ale Mongera
Happy birthday to #LaskerLaureate Christiane Nüsslein-Volhard! She identified 120 genes involved in specifying embryonic pattern development.
Read about the epic screen that yielded her Lasker Award-winning results: ow.ly/Pz2050PYFsz #WomenInSTEM 🧪
I Dreamt of Fruit Flies - Lasker Foundation
In the mid-1970s, Christiane Nüsslein-Volhard was struggling. Two years after finishing her PhD in molecular biology, she was working as a postdoctoral researcher in a lab she longed to leave. The…
ow.ly
October 20, 2025 at 4:32 PM
Reposted by Ale Mongera
We are hiring ! If you want to become professor of Bioinformatics in the best city of North America, check the announcement below ! Also you do need to speak French (as long as you commit to learning it :) ) www.umontreal.ca/public/www/d...
www.umontreal.ca
October 10, 2025 at 11:48 AM
Reposted by Ale Mongera
Can pressure gradients persist over long timescales in animal cells? We induced intracellular pressure gradients and examined the resulting flows in single cells. We reveal surprisingly long lasting pressure gradients.

More here: elifesciences.org/reviewed-pre...
elifesciences.org
September 29, 2025 at 8:45 AM
Super cool! Looking forward to trying this reporter!
🚨 Excited to introduce FuChi (Fucci chicken), the first avian cell cycle reporter line. Thank you to all those who contributed to putting this paper together. I really think it showcases the power and beauty of the chick embryo as a developmental biology model. 🐥 🥚 🔬 @roslininstitute.bsky.social
September 26, 2025 at 11:26 AM
📣Our project, “Mechanometabolic Control of Vertebrate Limb Elongation,” has been funded by Wellcome!
Over the next 8 years, we’ll collaborate with @manningresearch.bsky.social and Nathalie Agar’s group to understand the mechanics of ECM-rich mesenchymal tissues! Funded positions available!🎉
September 11, 2025 at 9:36 AM
Reposted by Ale Mongera
Everything (and more) you wanted to know about Nodal Signaling. A Paradigm for TGFβ Signaling in Embryonic Development | Annual Reviews - www.annualreviews.org/content/jour...
Nodal Signaling: A Paradigm for TGFβ Signaling in Embryonic Development | Annual Reviews
Nodal signaling molecules are TGFβ family ligands that arose early during bilaterian evolution and are crucial for several key steps in embryonic development. They regulate the specification of mesode...
www.annualreviews.org
August 10, 2025 at 2:16 PM
Reposted by Ale Mongera
Few spots left on our @bcube-tud.bsky.social organised hashtag #Symposium:
Engineering Life 2025: Origin and Function of Mechanical Forces in Biology ⚙️🧬

📆 September 1-3, 2025
📍 Steigenberger Hotel de Saxe, Dresden

Register now (Deadline 31 July 2025): engineering-life-dresden.de
July 28, 2025 at 3:44 PM
Reposted by Ale Mongera
Reposted by Ale Mongera
Somatic cells compartmentalise their metabolism to sustain germ cell survival https://www.biorxiv.org/content/10.1101/2025.07.22.666113v1
July 22, 2025 at 8:31 PM
Great thread by @amichaut.bsky.social
Check out this thread I wrote for @epimechfc.bsky.social ⬇️
If you’ve been following this account closely, you might already know methods to probe mechanics in vitro, but what about in live embryos?

I’m @amichaut.bsky.social, and I’m going to share a few great papers on this aspect of #EpithelialMechanics.
July 20, 2025 at 12:09 PM
Reposted by Ale Mongera
Check out this thread I wrote for @epimechfc.bsky.social ⬇️
If you’ve been following this account closely, you might already know methods to probe mechanics in vitro, but what about in live embryos?

I’m @amichaut.bsky.social, and I’m going to share a few great papers on this aspect of #EpithelialMechanics.
July 20, 2025 at 9:11 AM
Reposted by Ale Mongera
SARCOMERES divide! Mechanism how muscles grow while contracting - daughter sarcomeres appear everywhere. Seen live, registered on our cover. Pioneered by @clementrodier.bsky.social @friedrich-group.bsky.social Ian Estabrook @ibdm.bsky.social $ by @hfspo.bsky.social www.science.org/doi/10.1126/...
July 10, 2025 at 10:16 AM
Reposted by Ale Mongera
Why do vertex models work so well to predict tissue fluidity/rigidity, even though they are simple and possibly even wrong? A new paper in PRX Life
@prxlife.bsky.social, spearheaded by @sadjadarzash.bsky.social and Ojan Damavandi, suggests universality may explain: journals.aps.org/prxlife/abst...
Universality in the Mechanical Behavior of Vertex Models for Biological Tissues
A systematic comparison of diverse cell packing models reveals shared mechanical rules that govern how tissues stiffen, yield, and reorganize---shedding light on the physical logic behind morphogenesi...
journals.aps.org
July 9, 2025 at 12:10 AM
Reposted by Ale Mongera
SAVE THE DATE!! #2026SDB
🧪🧬🔬🧫🎉
(Never been to Vegas 😂 Exciting!!)
June 28, 2025 at 4:19 PM
Reposted by Ale Mongera
The Company of Biologists Workshop - Mechanometabolism Unleashed: The Interface of Cell Mechanics and Metabolism

Thank you to Workshop organisers Marco Foiani, Ana-Maria Lennon-Duménil, Victoria Sanz-Moreno and Giorgio Scita.

#Workshop #Biology #CellBiology #Community #Collaboration #Research
June 26, 2025 at 8:57 AM
Reposted by Ale Mongera
A closed feedback between tissue phase transitions and morphogen gradients drives patterning dynamics https://www.biorxiv.org/content/10.1101/2025.06.06.658228v1
June 6, 2025 at 12:31 PM
Reposted by Ale Mongera
Beautiful work as always from the @bhamlalab.bsky.social ! Flamingoes use swirling flows to trap and catch preys!
May 15, 2025 at 4:36 AM
Reposted by Ale Mongera
📢 Fresh off the press and featuring new exciting experiments! 🧪
We show how glycolytic activity instructs germ layer proportions through regulation of Nodal and Wnt signaling - happy to finally share this 😊
doi.org/10.1016/j.st...

B2B with @jesseveenvliet.bsky.social lab: doi.org/10.1016/j.st... 🤩
April 16, 2025 at 5:40 PM
Reposted by Ale Mongera
We're disappointed to see Ben Barres's powerful book "The Autobiography of a Transgender Scientist" among the ~400 titles removed from the Naval Academy Library. Needless to say, we're proud to have published his book and will keep it — and his memory — alive.
The Coming Out of a Transgender Scientist
"I know that I am making the right decision because whenever I think about changing my gender role, I am flooded with feelings of relief."
thereader.mitpress.mit.edu
April 8, 2025 at 8:24 PM
Reposted by Ale Mongera
Thrilled to share our new review article!
“The role of extracellular matrix viscoelasticity in development and disease” written together with Olivia Courbot is now published in npj Biological Physics and Mechanics. www.nature.com/articles/s44...
#ECM #Mechanobiology #DevelopmentalBiology
The role of extracellular matrix viscoelasticity in development and disease - npj Biological Physics and Mechanics
npj Biological Physics and Mechanics - The role of extracellular matrix viscoelasticity in development and disease
www.nature.com
April 7, 2025 at 8:42 AM
Amen
The Tariff rate is calculated the same way as the Impact Factor
April 3, 2025 at 3:49 PM