Marianna Karageorgi
@mkarag.bsky.social
Evolutionary geneticist
Adaptation to toxins across environments and timescales
K99 Fellow| Marie Curie Fellow
https://www.mariannakarageorgi.com/
Adaptation to toxins across environments and timescales
K99 Fellow| Marie Curie Fellow
https://www.mariannakarageorgi.com/
Pinned
Marianna Karageorgi
@mkarag.bsky.social
· Sep 15
Beneficial reversal of dominance maintains a large-effect resistance polymorphism under fluctuating insecticide selection - Nature Ecology & Evolution
Measuring selection and dominance in fitness of the insecticide-resistant Ace alleles in Drosophila melanogaster, the authors show evidence for beneficial reversal of dominance, a mechanism that can s...
www.nature.com
How do populations maintain an evolutionary memory? I am happy to share that our work with Dmitri Petrov @petrovadmitri.bsky.social, Paul Schmidt, and colleagues on dominance reversal and stabilization of insecticide resistance in changing environments over time is now published at Nature EE.
Reposted by Marianna Karageorgi
My main PhD work @monteirolab.bsky.social is now in @natecoevo.nature.com! We found a Hox gene promoter that helps butterflies🦋adjust their wing eyespots in response to seasonal temperatures🍃🍂, shedding light on the evolutionary origin of phenotypic plasticity. 1/9 www.nature.com/articles/s41...
October 24, 2025 at 10:16 AM
My main PhD work @monteirolab.bsky.social is now in @natecoevo.nature.com! We found a Hox gene promoter that helps butterflies🦋adjust their wing eyespots in response to seasonal temperatures🍃🍂, shedding light on the evolutionary origin of phenotypic plasticity. 1/9 www.nature.com/articles/s41...
Reposted by Marianna Karageorgi
How is functional variation at large-effect loci maintained in natural populations, even as environments change? In a paper led by @mkarag.bsky.social, we tracked known pesticide resistant alleles in outdoor 𝘋. 𝘮𝘦𝘭𝘢𝘯𝘰𝘨𝘢𝘴𝘵𝘦𝘳 cages & inferred selection and dominance from temporal sequencing data.
November 6, 2025 at 9:51 PM
How is functional variation at large-effect loci maintained in natural populations, even as environments change? In a paper led by @mkarag.bsky.social, we tracked known pesticide resistant alleles in outdoor 𝘋. 𝘮𝘦𝘭𝘢𝘯𝘰𝘨𝘢𝘴𝘵𝘦𝘳 cages & inferred selection and dominance from temporal sequencing data.
"The most transformative technologies, ..., emerged not from goal-directed efforts but from foundational inquiries with no predetermined outcomes." #curiosity-driven_science
For the love of frontier research, or why Elon’s rockets keep blowing up | EMBO reports
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
www.embopress.org
October 23, 2025 at 2:55 PM
"The most transformative technologies, ..., emerged not from goal-directed efforts but from foundational inquiries with no predetermined outcomes." #curiosity-driven_science
Reposted by Marianna Karageorgi
So this came online over the weekend: My dive into the "definition" of coevolution is online ahead of publication in @journal-evo.bsky.social!
Don’t ask "when is it coevolution?" — ask "how?"
doi.org/10.1093/evol...
Don’t ask "when is it coevolution?" — ask "how?"
doi.org/10.1093/evol...
Don’t ask “when is it coevolution?” — ask “how?”
Abstract. Coevolution has come to be widely understood as specific, simultaneous, reciprocal adaptation by pairs of interacting species. This strict-sense
doi.org
September 30, 2025 at 3:30 PM
So this came online over the weekend: My dive into the "definition" of coevolution is online ahead of publication in @journal-evo.bsky.social!
Don’t ask "when is it coevolution?" — ask "how?"
doi.org/10.1093/evol...
Don’t ask "when is it coevolution?" — ask "how?"
doi.org/10.1093/evol...
Preschool teachers provide fewer participation opportunities to working-class students than those from more privileged backgrounds | PNAS www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
September 24, 2025 at 7:29 PM
Preschool teachers provide fewer participation opportunities to working-class students than those from more privileged backgrounds | PNAS www.pnas.org/doi/10.1073/...
Reposted by Marianna Karageorgi
Save the date! #PEQG26 June 9-12 2026 in Asilomar, CA. Happens only every 2yrs, but is my favorite conference. Full website coming soon, and registration and abstract submission opens November 14, but I'm allowed to tease that keynotes will be @jnovembre.bsky.social @jennytung.bsky.social and me!
Homepage - Population, Evolutionary, and Quantitative Genetics Conference
Visit our website to learn more.
genetics-gsa.org
September 3, 2025 at 6:51 PM
Save the date! #PEQG26 June 9-12 2026 in Asilomar, CA. Happens only every 2yrs, but is my favorite conference. Full website coming soon, and registration and abstract submission opens November 14, but I'm allowed to tease that keynotes will be @jnovembre.bsky.social @jennytung.bsky.social and me!
Reposted by Marianna Karageorgi
Very excited to see this work in press! I think there is a reason to believe that this is a common means of stabilizing large-effect polymorphisms in general and might be an important reason for why diploidy is so common. news.stanford.edu/stories/2025...
September 15, 2025 at 5:24 PM
Very excited to see this work in press! I think there is a reason to believe that this is a common means of stabilizing large-effect polymorphisms in general and might be an important reason for why diploidy is so common. news.stanford.edu/stories/2025...
How do populations maintain an evolutionary memory? I am happy to share that our work with Dmitri Petrov @petrovadmitri.bsky.social, Paul Schmidt, and colleagues on dominance reversal and stabilization of insecticide resistance in changing environments over time is now published at Nature EE.
Beneficial reversal of dominance maintains a large-effect resistance polymorphism under fluctuating insecticide selection - Nature Ecology & Evolution
Measuring selection and dominance in fitness of the insecticide-resistant Ace alleles in Drosophila melanogaster, the authors show evidence for beneficial reversal of dominance, a mechanism that can s...
www.nature.com
September 15, 2025 at 6:17 PM
How do populations maintain an evolutionary memory? I am happy to share that our work with Dmitri Petrov @petrovadmitri.bsky.social, Paul Schmidt, and colleagues on dominance reversal and stabilization of insecticide resistance in changing environments over time is now published at Nature EE.
Reposted by Marianna Karageorgi
August’s Nature Plants cover story shows how we integrated large-scale multiDAP and snRNA data to reveal drivers of cell type identity and evolution in flowering plants. www.nature.com/nplants/volu... We packed a lot into this paper! Here’s a single-cell spin on what we found:
Nature Plants - Cistromes uncovered
Transcription factors (TFs) have specific patterns of binding to gene promoter regions, which have similarities and differences within TF families and...
www.nature.com
August 19, 2025 at 11:08 PM
August’s Nature Plants cover story shows how we integrated large-scale multiDAP and snRNA data to reveal drivers of cell type identity and evolution in flowering plants. www.nature.com/nplants/volu... We packed a lot into this paper! Here’s a single-cell spin on what we found:
Earlier in summer, there was a gigantic 4-year longitudinal study in France showing that the school environment triggers a gender gap in mathematics. www.nature.com/articles/s41...
August 10, 2025 at 8:29 PM
Earlier in summer, there was a gigantic 4-year longitudinal study in France showing that the school environment triggers a gender gap in mathematics. www.nature.com/articles/s41...
I was down at Pacific Grove last weekend and a volunteer shared the monarch population is declining.. #pesticides #land_use_change
Monarch butterflies’ mass die-off in 2024 caused by pesticide exposure – study
New peer-reviewed research found an average of seven pesticides in each of 10 butterflies tested
www.theguardian.com
August 1, 2025 at 9:12 PM
I was down at Pacific Grove last weekend and a volunteer shared the monarch population is declining.. #pesticides #land_use_change
Reposted by Marianna Karageorgi
check out my new article published in @nautil.us on Sewall Wright's famous shifting-balance theory of evolution, told through the lens of his work with guinea pigs!
nautil.us/evolution-an...
nautil.us/evolution-an...
Evolution and Guinea Pig Toes
How one animal's oddity inspired Sewall Wright to take on one of Darwin's big ideas
nautil.us
June 12, 2025 at 3:47 PM
check out my new article published in @nautil.us on Sewall Wright's famous shifting-balance theory of evolution, told through the lens of his work with guinea pigs!
nautil.us/evolution-an...
nautil.us/evolution-an...
Reposted by Marianna Karageorgi
#Invertefest?! Okay!
This one is a personal favorite out of all my bug art.
This one is a personal favorite out of all my bug art.
April 24, 2025 at 7:13 PM
#Invertefest?! Okay!
This one is a personal favorite out of all my bug art.
This one is a personal favorite out of all my bug art.
Reposted by Marianna Karageorgi
Just noticed this in last Sunday’s Observer, a week in the life of an Orange-tip as told to Simon Barnes. Brilliant.
May 3, 2025 at 6:09 PM
Just noticed this in last Sunday’s Observer, a week in the life of an Orange-tip as told to Simon Barnes. Brilliant.
Reposted by Marianna Karageorgi
Scientists have recently mapped the painted lady butterfly's annual flight from equatorial Africa to northern Europe and back, the world's longest butterfly migration. In Constant Bloom, photographer Lucas Foglia documents the journey.
Photos: Scientists trace a butterfly migration route that is millions of years old
Scientists have recently mapped the painted lady butterfly's annual flight from equatorial Africa to northern Europe and back, the world's longest butterfly migration. In Constant Bloom, photographer ...
www.npr.org
April 17, 2025 at 1:52 AM
Scientists have recently mapped the painted lady butterfly's annual flight from equatorial Africa to northern Europe and back, the world's longest butterfly migration. In Constant Bloom, photographer Lucas Foglia documents the journey.
Inferring Balancing Selection From Genome-Scale Data
Inferring Balancing Selection From Genome-Scale Data
Abstract. The identification of genomic regions and genes that have evolved under natural selection is a fundamental objective in the field of evolutionary
academic.oup.com
April 18, 2025 at 5:39 PM
Inferring Balancing Selection From Genome-Scale Data
Reposted by Marianna Karageorgi
For Women's History Month, may we all remember and summon the courage of Rachel Carson, who wrote Silent Spring to inform the world what DDT was doing to the songbirds, raptors,and by extension, us. While battling cancer, she stood her ground against savage attacks by the chemical industry...
March 10, 2025 at 3:52 PM
For Women's History Month, may we all remember and summon the courage of Rachel Carson, who wrote Silent Spring to inform the world what DDT was doing to the songbirds, raptors,and by extension, us. While battling cancer, she stood her ground against savage attacks by the chemical industry...
Reposted by Marianna Karageorgi
The PopGen Vienna Seminar series schedule is ready for the next term (Mar-Jun). It's jam-packed with fantastic speakers in #evolution, #genetics, #genomics, #popgen, and more! Details and streaming link signup can be found on our website www.popgen-vienna.at/news/seminars/
February 13, 2025 at 3:01 PM
The PopGen Vienna Seminar series schedule is ready for the next term (Mar-Jun). It's jam-packed with fantastic speakers in #evolution, #genetics, #genomics, #popgen, and more! Details and streaming link signup can be found on our website www.popgen-vienna.at/news/seminars/
A century of theories of balancing selection www.biorxiv.org/content/10.1...
A century of theories of balancing selection
Traits that affect organismal fitness are often very genetically variable. This genetic variation is vital for populations to adapt to their environments, but it is also surprising given that nature (...
www.biorxiv.org
February 17, 2025 at 1:38 AM
A century of theories of balancing selection www.biorxiv.org/content/10.1...
How is functional variation at large-effect loci maintained in natural populations?
Thrilled to share our work showing how beneficial dominance reversal helps fruit flies maintain a resistance polymorphism as selection varies in their environment! A thread 🧵 1/n
www.biorxiv.org/content/10.1...
Thrilled to share our work showing how beneficial dominance reversal helps fruit flies maintain a resistance polymorphism as selection varies in their environment! A thread 🧵 1/n
www.biorxiv.org/content/10.1...
Dominance reversal maintains large-effect resistance polymorphism in temporally varying environments
A central challenge in evolutionary biology is to uncover mechanisms maintaining functional genetic variation1. Theory suggests that dominance reversal, whereby alleles subject to fluctuating selectio...
www.biorxiv.org
January 22, 2025 at 7:44 PM
How is functional variation at large-effect loci maintained in natural populations?
Thrilled to share our work showing how beneficial dominance reversal helps fruit flies maintain a resistance polymorphism as selection varies in their environment! A thread 🧵 1/n
www.biorxiv.org/content/10.1...
Thrilled to share our work showing how beneficial dominance reversal helps fruit flies maintain a resistance polymorphism as selection varies in their environment! A thread 🧵 1/n
www.biorxiv.org/content/10.1...