A noncanonical Hippo kinase, STK38, degrades YAP1 at homeostasis.
Autophagy in stage 1 degrades STK38 to activate YAP1 for metaplasia and proliferation (stages 2 and 3).
A noncanonical Hippo kinase, STK38, degrades YAP1 at homeostasis.
Autophagy in stage 1 degrades STK38 to activate YAP1 for metaplasia and proliferation (stages 2 and 3).