5/5 In summary, SNHG8 and FAM151B‑DT play complementary roles in tauopathies: SNHG8 limits stress granules that drive tau aggregation, while FAM151B‑DT enhances clearance of toxic proteins, opening new paths for understanding and treating tau-related disease. 🧫🔬🧐
#Neuroscience #Tauopathies #endFTD

3/5 Both SNHG8 and FAM151B-DT are reduced in neurons with pathogenic MAPT mutations and in brains from patients with tauopathies such as FTLD, PSP, and AD, linking these lncRNAs broadly to tau-related neurodegeneration. 🧠🧪
#Neuroscience #Tauopathies #endFTD

2/5 SNHG8 and FAM151B DT are key targets to restore protein balance and reduce toxic protein buildup in neurodegenerative diseases. Promising steps toward new therapies! 🔬🥼🧫 #Tauopathies #endFTD

1/5 Hey friends! Exciting news! Two new studies highlight the role of lncRNAs SNHG8 & FAM151B DT in tau-related brain disorders. These discoveries open new paths for research & therapy. 🔬📚 #Tauopathies #endFTD
Read more:
🔗 pubmed.ncbi.nlm.nih.gov/37730840/
🔗 pubmed.ncbi.nlm.nih.gov/41053434/