Michael Lazear
@michaellazear.bsky.social
I like big data and I cannot lie | Informatics/ML lead @ Belharra Tx, wet lab PhD @ Cravatt Lab
Reposted by Michael Lazear
🧪 Transforming biomedical discovery needs proteomics that is specific and accurate, but also faster and cheaper
@parallelsq.bsky.social is proud to introduce 9-plex PSMtags: a new mass tag that improves sequencing and increases throughput in sensitive proteomics 👇
www.biorxiv.org/content/10.1...
@parallelsq.bsky.social is proud to introduce 9-plex PSMtags: a new mass tag that improves sequencing and increases throughput in sensitive proteomics 👇
www.biorxiv.org/content/10.1...
www.biorxiv.org
May 28, 2025 at 12:21 PM
🧪 Transforming biomedical discovery needs proteomics that is specific and accurate, but also faster and cheaper
@parallelsq.bsky.social is proud to introduce 9-plex PSMtags: a new mass tag that improves sequencing and increases throughput in sensitive proteomics 👇
www.biorxiv.org/content/10.1...
@parallelsq.bsky.social is proud to introduce 9-plex PSMtags: a new mass tag that improves sequencing and increases throughput in sensitive proteomics 👇
www.biorxiv.org/content/10.1...
Reposted by Michael Lazear
@michaellazear.bsky.social & @jspaezp.bsky.social I'm Running Sage on a dual Epyc 128 thread box w/ 2TB memory (I think) . Searching 19 ddaPASF files directly with built in timsRUST!! Dang this is screaming fast !!
January 22, 2025 at 2:43 AM
@michaellazear.bsky.social & @jspaezp.bsky.social I'm Running Sage on a dual Epyc 128 thread box w/ 2TB memory (I think) . Searching 19 ddaPASF files directly with built in timsRUST!! Dang this is screaming fast !!
Reposted by Michael Lazear
Chiang and Collins making a fun Casanovo + Sage (w/Mokapot et al.) metaproteomics pipeline (Bittremieux, @michaellazear.bsky.social @willfondrie.com) … and an exceptional TOC graphic.
Orthrus: an AI-powered, cloud-ready, and open-source hybrid approach for metaproteomics www.biorxiv.org/cont...
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#proteomics #prot-preprint
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#proteomics #prot-preprint
November 16, 2024 at 12:53 PM
Chiang and Collins making a fun Casanovo + Sage (w/Mokapot et al.) metaproteomics pipeline (Bittremieux, @michaellazear.bsky.social @willfondrie.com) … and an exceptional TOC graphic.
Trying to do some research for buying a new road bike and I have stumbled upon something truly cursed... what appears to a forum of just LLMs talking to one another: www.cyclingforums.com/threads/gian...
November 14, 2024 at 5:48 AM
Trying to do some research for buying a new road bike and I have stumbled upon something truly cursed... what appears to a forum of just LLMs talking to one another: www.cyclingforums.com/threads/gian...
Reposted by Michael Lazear
This is Big for #quantms team. Let me explain some of the big improvements:
- Sage integration thanks to @michaellazear.bsky.social
- Bruker and library based DIA support thanks to @jspaezp.bsky.social
- Major improvements in LFQ pipeline and pmultiqc reports.
- Lot of bugs fixed from version 1.1.1.
- Sage integration thanks to @michaellazear.bsky.social
- Bruker and library based DIA support thanks to @jspaezp.bsky.social
- Major improvements in LFQ pipeline and pmultiqc reports.
- Lot of bugs fixed from version 1.1.1.
Pipeline release! nf-core/quantms v1.2.0 - nfcore/quantms v1.2.0 - Thimphu!
Please see the changelog: https://github.com/nf-core/quantms/releases/tag/1.2.0
Please see the changelog: https://github.com/nf-core/quantms/releases/tag/1.2.0
November 2, 2023 at 8:15 PM
This is Big for #quantms team. Let me explain some of the big improvements:
- Sage integration thanks to @michaellazear.bsky.social
- Bruker and library based DIA support thanks to @jspaezp.bsky.social
- Major improvements in LFQ pipeline and pmultiqc reports.
- Lot of bugs fixed from version 1.1.1.
- Sage integration thanks to @michaellazear.bsky.social
- Bruker and library based DIA support thanks to @jspaezp.bsky.social
- Major improvements in LFQ pipeline and pmultiqc reports.
- Lot of bugs fixed from version 1.1.1.
Reposted by Michael Lazear
I’ve never seen someone with such polished twitter threads, which have now been rolled into a JPR paper. I think @michaellazear.bsky.social is on to something great with SAGE, especially its openness. Looking forward to seeing this engine powering proteomics.
(h/t @pastelbio.bsky.social)
(h/t @pastelbio.bsky.social)
Sage: An Open-Source Tool for Fast Proteomics Searching and Quantification at Scale
The growing complexity and volume of proteomics data necessitate the development of efficient software tools for peptide identification and quantification from mass spectra. Given their central role i...
pubs.acs.org
October 12, 2023 at 8:51 AM
I’ve never seen someone with such polished twitter threads, which have now been rolled into a JPR paper. I think @michaellazear.bsky.social is on to something great with SAGE, especially its openness. Looking forward to seeing this engine powering proteomics.
(h/t @pastelbio.bsky.social)
(h/t @pastelbio.bsky.social)