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michaelbatie.bsky.social
@michaelbatie.bsky.social
Reposted
Really excited to share our latest pre-prints! Great collaborative work, amazing imaging from Jimena, proteomics from Hao, biochemistry from Dilem and so on!
www.biorxiv.org/content/10.1...
PHD1-dependent hydroxylation of RepoMan (CDCA2) on P604 modulates the control of mitotic progression
Prolyl-hydroxylases (PHDs) are oxygen sensing enzymes that mediate the hydroxylation of proline residues. In mammals, three PHD isoforms (PHD1-3) are responsible for proline hydroxylation of Hypoxia I...
www.biorxiv.org
May 13, 2025 at 1:39 PM
Reposted
Also with a updated version of our methods manuscript for this amazing PTM!
www.biorxiv.org/content/10.1...
May 13, 2025 at 1:40 PM
Reposted
Delighted to finally share our latest preprint on the role of NF-kappaB in hypoxia. Quite a few surprises!! www.biorxiv.org/content/10.1...
Have a look!
NF-κB is a Central Regulator of Hypoxia-Induced Gene Expression
Hypoxia is both a physiological and pathological signal in cells. Changes in gene expression play a critical role in the cellular response to hypoxia, enabling cells to adapt to reduced oxygen availab...
www.biorxiv.org
January 9, 2025 at 10:57 AM