Michael Murphy
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michael-murphy32.bsky.social
Michael Murphy
@michael-murphy32.bsky.social
Irish trained Neurologist, current Clinical Research Fellow and PhD candidate at Queen Square Institute of Neurology.
Reposted by Michael Murphy
We are delighted to present the first publication out of the lab, available online today, titled ‘Evaluating finger-prick blood collection for remote quantification of neurofilament light in neurological diseases’ link.springer.com/article/10.1...
Evaluating finger-prick blood collection for remote quantification of neurofilament light in neurological diseases - Journal of Neurology
Promising blood-based biomarkers of neuropathology have emerged with potential for therapeutic development and disease monitoring. However, these tools will require specialist tertiary services for in...
link.springer.com
July 10, 2025 at 4:42 PM
Reposted by Michael Murphy
Somatic CAG repeat expansion in blood associates with biomarkers of neurodegeneration in Huntington’s disease decades before clinical motor diagnosis www.nature.com/articles/s41...
Somatic CAG repeat expansion in blood associates with biomarkers of neurodegeneration in Huntington’s disease decades before clinical motor diagnosis - Nature Medicine
A comprehensive longitudinal analysis of individuals with preclinical Huntington’s disease identifies biomarkers of neurodegeneration and somatic expansion in blood DNA, detectable years before sympto...
www.nature.com
January 20, 2025 at 9:56 AM
Reposted by Michael Murphy
Excited to share my joint first-author paper (with @rachiscahill.bsky.social) published today in Nature Medicine (@natmedicine.bsky.social, @nature.com). Our findings are timely as the #HD therapeutic landscape expands toward preventive clinical trials. 🔓 Open access: www.nature.com/articles/s41...
Somatic CAG repeat expansion in blood associates with biomarkers of neurodegeneration in Huntington’s disease decades before clinical motor diagnosis - Nature Medicine
A comprehensive longitudinal analysis of individuals with preclinical Huntington’s disease identifies biomarkers of neurodegeneration and somatic expansion in blood DNA, detectable years before sympto...
www.nature.com
January 17, 2025 at 11:00 AM