Michael Pereira
@meaperei.bsky.social
INSERM scientist in Grenoble; perceptual consciousness and metacognition with invasive electrophysiology and single neuron recordings (in humans); http://mpereira.me
4/6 Interestingly, we found a bimodal distribution of neuronal response latencies:
⏱ One early cluster ~ 120–150 ms
⏱ One late cluster ~ 315–330 ms
This was true for both sensory- and perception-selective neurons.
⏱ One early cluster ~ 120–150 ms
⏱ One late cluster ~ 315–330 ms
This was true for both sensory- and perception-selective neurons.
June 1, 2025 at 4:35 PM
4/6 Interestingly, we found a bimodal distribution of neuronal response latencies:
⏱ One early cluster ~ 120–150 ms
⏱ One late cluster ~ 315–330 ms
This was true for both sensory- and perception-selective neurons.
⏱ One early cluster ~ 120–150 ms
⏱ One late cluster ~ 315–330 ms
This was true for both sensory- and perception-selective neurons.
3/6 We labeled (putative) single neurons as:
🔹 Sensory-selective — firing changed after stimulus onset.
🔹 Perception-selective — firing differed between detected and missed stimuli.
🔹 Sensory-selective — firing changed after stimulus onset.
🔹 Perception-selective — firing differed between detected and missed stimuli.
June 1, 2025 at 4:35 PM
3/6 We labeled (putative) single neurons as:
🔹 Sensory-selective — firing changed after stimulus onset.
🔹 Perception-selective — firing differed between detected and missed stimuli.
🔹 Sensory-selective — firing changed after stimulus onset.
🔹 Perception-selective — firing differed between detected and missed stimuli.
2/6 During surgeries, microelectrode recordings guide targeting.
Meanwhile, we estimated patients’ tactile threshold and had them perform a 10-minute detection task. We recorded from the thalamus and subthalamic nucleus, maintaining a detection rate of ~50% using an adaptive procedure.
Meanwhile, we estimated patients’ tactile threshold and had them perform a 10-minute detection task. We recorded from the thalamus and subthalamic nucleus, maintaining a detection rate of ~50% using an adaptive procedure.
June 1, 2025 at 4:35 PM
2/6 During surgeries, microelectrode recordings guide targeting.
Meanwhile, we estimated patients’ tactile threshold and had them perform a 10-minute detection task. We recorded from the thalamus and subthalamic nucleus, maintaining a detection rate of ~50% using an adaptive procedure.
Meanwhile, we estimated patients’ tactile threshold and had them perform a 10-minute detection task. We recorded from the thalamus and subthalamic nucleus, maintaining a detection rate of ~50% using an adaptive procedure.
1/6 Recording single neurons in subcortical regions of the human 🧠 during cognitive tasks is pretty rare and challenging.
We utilized microelectrode recordings during deep brain stimulation (DBS) surgeries to investigate how these neurons may encode tactile perception.
We utilized microelectrode recordings during deep brain stimulation (DBS) surgeries to investigate how these neurons may encode tactile perception.
June 1, 2025 at 4:35 PM
1/6 Recording single neurons in subcortical regions of the human 🧠 during cognitive tasks is pretty rare and challenging.
We utilized microelectrode recordings during deep brain stimulation (DBS) surgeries to investigate how these neurons may encode tactile perception.
We utilized microelectrode recordings during deep brain stimulation (DBS) surgeries to investigate how these neurons may encode tactile perception.