Maxwell Shafer
maxshafer.bsky.social
Maxwell Shafer
@maxshafer.bsky.social
Assistant Professor UofT Cell & Systems Biology - 🐟🐠🐡 comparative genomics/ethology & evolutionary cell biology of sleep 💤 😴 + adventures with @hilsawh - https://csb.utoronto.ca/faculty/maxwell-shafer/
Reposted by Maxwell Shafer
This is just the first effort of our foray into cichlid behaviour and genetics! If you are interested in working on the evolution, genomics, and neurobiology of sleep and chronobiology @uoftcellsysbiol.bsky.social in beautiful Toronto, please reach out! shafer-lab.netlify.app
Sleep Evolution Group
A highly-customizable Hugo research group theme powered by Wowchemy website builder.
shafer-lab.netlify.app
August 28, 2025 at 2:18 PM
This is just the first effort of our foray into cichlid behaviour and genetics! If you are interested in working on the evolution, genomics, and neurobiology of sleep and chronobiology @uoftcellsysbiol.bsky.social in beautiful Toronto, please reach out! shafer-lab.netlify.app
Sleep Evolution Group
A highly-customizable Hugo research group theme powered by Wowchemy website builder.
shafer-lab.netlify.app
August 28, 2025 at 2:18 PM
Thanks to all my coauthors, including my first two grad students in Toronto, Amelia & Ayasha; thanks to @schierlab.bsky.social and Walter Salzburger as always for everything; and many huge thanks to @annika-nichols.bsky.social, who is my co-first-author and forever friend and colleague!!
August 28, 2025 at 2:18 PM
Finally, we took advantage of extensive genomic data already generated by the Salzburger group to link activity and sleep phenotypes to genomic loci - intriguingly, they were not enriched for clock genes as hypothesised, but synaptic genes, and genes associated with neurological diseases in humans!
August 28, 2025 at 2:18 PM
We hypothesise that these activity patterns represent a novel axis upon which these species diversified, leading to multiple temporal versions of each eco-morphological niche, and facilitating their rapid adaptive diversification!
August 28, 2025 at 2:18 PM
Some, like the algivorous O. boops, sleep 𝗼𝗻𝗹𝘆 𝟮 𝗵𝗿𝘀 𝗮 𝗱𝗮𝘆, whereas others, like the mud hole dwelling L. signatus, 𝘀𝗹𝗲𝗲𝗽 𝘂𝗽 𝘁𝗼 𝟭𝟱 𝗵𝗿𝘀 𝗮 𝗱𝗮𝘆!
August 28, 2025 at 2:18 PM
(above video) we tracked hundreds of individual fish in the lab across 6 days and 6 nights from 60 species of cichlids from Lake Tanganyika - and discovered that they exhibit all known activity patterns (diurnal, nocturnal, crepuscular, and cathemeral)...
August 28, 2025 at 2:18 PM