This evening I'll be presenting our work on MBD4 knockout as a tool for modelling mutagenesis and clonal outgrowth at the poster session of #EHA2025. Come visit me at PF1115 if you're interested! #Hemesky 🩸🧪

Enjoyed last week's KWF Dutch Cancer Biology Meeting in the forests 🌳 of Lunteren where I got the opportunity to present on DNMT3A double mutant AML.
@dpastoors.bsky.social gave nice talk on p300&CBP regulating enhancer activity in AML which was awarded with the Best Presentation Award! 🤩🥳
#Hemesky

Finally out! 🤩🎆

In this work we describe DNMT3A double mutant AML as an unique subtype with a poor prognosis and high levels of methylation damage.

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ashpublications.org/bloodadvance...

Interested in how DNMT3A mutations affect the DNA demethylation pathways in AML? Come find me at poster 2718 tonight! #hemesky #ASH24

About a year ago @dpastoors.bsky.social and I started to fill up the empty wall in our office by adding a 'meme of the week' on every Monday morning. With the Christmas break coming up soon, here's this week's addition for you :)