mariaefrancia.bsky.social
@mariaefrancia.bsky.social
Reposted
🚨New Research: Adverse impact of acute Toxoplasma gondii infection on human spermatozoa- The FEBS Journal - febs.onlinelibrary.wiley.com/doi/10.1111/.... Thanks to @mariaefrancia.bsky.social Lab and all wonderful people who collaborate to make this possible. Here below what we found :).
FEBS Press
Toxoplasma gondii tachyzoites injected intraperitoneally crossed the blood-testes barrier, appearing in testes/epididymis by day 6 post-infection. In vitro exposure caused increased sperm necrosis/ap...
febs.onlinelibrary.wiley.com
May 4, 2025 at 8:54 AM
Reposted
Thrilled to share my first paper, now out in
@natmicrobiol.nature.com! Huge thanks to my amazing supervisor @hakimi.bsky.social and everyone who contributed to this work!

www.nature.com/articles/s41...
An ISWI-related chromatin remodeller regulates stage-specific gene expression in Toxoplasma gondii - Nature Microbiology
Toxoplasma gondii evolved two ISWI remodellers, TgSNF2h and TgSNF2L. TgSNF2h forms a complex that insulates active genes, regulates MORC-driven sexual commitment and ensures precise gene expression, s...
www.nature.com
April 13, 2025 at 11:03 AM
Reposted
Thrilled to have this out now! Go checkout our paper about the crazy #Toxoplasma #mitoribosome. Huge thanks to co-authors, collaborators and everyone involved 🙌
Remember learning that ribosomes are made of 1 large subunit RNA + 1 small subunit RNA?
Well, some cells defy this rule, and the most extreme case is Toxoplasma which makes its mitoribosome from >50 RNA pieces!
Wanna know how? Read below
January 21, 2025 at 6:08 PM
Reposted
Cascading expression of ApiAP2 transcription factors controls daughter cell assembly in Toxoplasma gondii

journals.plos.org/plospathogen...
Cascading expression of ApiAP2 transcription factors controls daughter cell assembly in Toxoplasma gondii
Author summary Toxoplasma gondii is a is a unicellular eukaryotic pathogen that infects a wide range of animals. Pathogenesis of this parasite relies on its ability to rapidly proliferate and dissemin...
journals.plos.org
January 11, 2025 at 2:56 PM
Reposted
Stranded short nascent strand sequencing reveals the topology of eukaryotic DNA replication origins in Trypanosoma brucei. https://www.biorxiv.org/content/10.1101/2024.12.03.626629v1
December 7, 2024 at 1:32 AM