@madelinebacon.bsky.social
Reposted
🚨New preprint alert🚨
We used closed-loop optogenetics to causally test the importance of inhibitory spike timing in network function and found that manipulating PV+ cell theta phase locking in the dentate gyrus can shift seizure susceptibility (both ways!)
We used closed-loop optogenetics to causally test the importance of inhibitory spike timing in network function and found that manipulating PV+ cell theta phase locking in the dentate gyrus can shift seizure susceptibility (both ways!)
September 11, 2025 at 5:07 PM
🚨New preprint alert🚨
We used closed-loop optogenetics to causally test the importance of inhibitory spike timing in network function and found that manipulating PV+ cell theta phase locking in the dentate gyrus can shift seizure susceptibility (both ways!)
We used closed-loop optogenetics to causally test the importance of inhibitory spike timing in network function and found that manipulating PV+ cell theta phase locking in the dentate gyrus can shift seizure susceptibility (both ways!)
Reposted
What’s better than a one-channel #Miniscope? 🥁 A TWO-CHANNEL Miniscope!
Our new Miniscope2C is a dual-channel, open-source Miniscope that lets you record 2 fluorescent signals simultaneously in freely moving animals.
Read the paper here: www.science.org/doi/10.1126/...
(1/10)
Our new Miniscope2C is a dual-channel, open-source Miniscope that lets you record 2 fluorescent signals simultaneously in freely moving animals.
Read the paper here: www.science.org/doi/10.1126/...
(1/10)
July 14, 2025 at 4:55 PM
What’s better than a one-channel #Miniscope? 🥁 A TWO-CHANNEL Miniscope!
Our new Miniscope2C is a dual-channel, open-source Miniscope that lets you record 2 fluorescent signals simultaneously in freely moving animals.
Read the paper here: www.science.org/doi/10.1126/...
(1/10)
Our new Miniscope2C is a dual-channel, open-source Miniscope that lets you record 2 fluorescent signals simultaneously in freely moving animals.
Read the paper here: www.science.org/doi/10.1126/...
(1/10)
Reposted
The Cai Lab is at @mpfneuro.bsky.social's Emerging Neurotechnology course this week, running a #Miniscope workshop. The course kicked off Monday with an AMAZING keynote by Nobel Laureate @stefanhelllabs.bsky.social.
Looking forward to the rest of the week’s activities! 🤓 #Neuroskyence
Looking forward to the rest of the week’s activities! 🤓 #Neuroskyence
April 16, 2025 at 8:47 PM
The Cai Lab is at @mpfneuro.bsky.social's Emerging Neurotechnology course this week, running a #Miniscope workshop. The course kicked off Monday with an AMAZING keynote by Nobel Laureate @stefanhelllabs.bsky.social.
Looking forward to the rest of the week’s activities! 🤓 #Neuroskyence
Looking forward to the rest of the week’s activities! 🤓 #Neuroskyence
Reposted
And check out how we used chemotagging to characterize how interneurons integrate memories across time: www.nature.com/articles/s41...
Thank you to @bumjinko.bsky.social, @madelinebacon.bsky.social & @joezaki.bsky.social for all their hard work on developing this versatile technique! 🎉
Thank you to @bumjinko.bsky.social, @madelinebacon.bsky.social & @joezaki.bsky.social for all their hard work on developing this versatile technique! 🎉
Offline ensemble co-reactivation links memories across days - Nature
In mice, a strong aversive experience drives offline ensemble reactivation of not only the recent aversive memory but also a neutral memory formed 2 days before, linking fear of the recent aversive me...
www.nature.com
January 15, 2025 at 6:35 PM
And check out how we used chemotagging to characterize how interneurons integrate memories across time: www.nature.com/articles/s41...
Thank you to @bumjinko.bsky.social, @madelinebacon.bsky.social & @joezaki.bsky.social for all their hard work on developing this versatile technique! 🎉
Thank you to @bumjinko.bsky.social, @madelinebacon.bsky.social & @joezaki.bsky.social for all their hard work on developing this versatile technique! 🎉
Reposted
New paper out in Cell Reports! Led by @susieyufeng.bsky.social, we found that chronic epilepsy in mice drives distinct synchronization deficits in hippocampus and MEC, with early changes in HPC and late-onset changes in MEC that align with progressive memory impairment.
www.cell.com/cell-reports...
www.cell.com/cell-reports...
January 28, 2025 at 8:17 PM
New paper out in Cell Reports! Led by @susieyufeng.bsky.social, we found that chronic epilepsy in mice drives distinct synchronization deficits in hippocampus and MEC, with early changes in HPC and late-onset changes in MEC that align with progressive memory impairment.
www.cell.com/cell-reports...
www.cell.com/cell-reports...