m-joe.bsky.social
@m-joe.bsky.social
Reposted
Excited to share our laboratory's research tools to study Siglecs along with some interesting discoveries with these tools. Lot of help from many group, but @zeinab-jc.bsky.social was the major driver of this work. Please reach out if you would like to try them out. www.science.org/doi/10.1126/...
An ultrasensitive and modular platform to detect Siglec ligands and control immune cell function
Siglec-liposomes are a multivalent and modular platform for profiling Siglec ligands and modulating immune cell function.
www.science.org
November 12, 2025 at 9:57 PM
Reposted
“No government that purports to uphold the rule of law and fundamental rights and freedoms of its citizens would ever take away the right to free collective bargaining and the right to strike."
The Canadian Association of University Teachers condemns the Alberta government for overriding constitutionally protected rights and imposing a rejected contract offer on members of the Alberta Teachers’ Association.

Read more: www.caut.ca/news/caut-co...
October 29, 2025 at 3:30 PM
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Canada’s bail and sentencing laws are about to get a lot tougher.
 
We’re amending the Criminal Code to help keep violent criminals and repeat offenders off our streets, and we’re introducing stronger sentences for auto-theft, organised crime, and home invasion.
October 16, 2025 at 6:43 PM
Reposted
August 22, 2025 at 11:46 PM
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Very excited to share some work the Lab has been working on for a while. A new platform to probe Siglec ligands. Led by an incredible PhD student (Zeinab). Comes out of an ongoing fruitful collaboration with the Derda lab. Very open to feedback! www.biorxiv.org/content/10.1...
An ultrasensitive and modular platform to detect Siglec ligands and control immune cell function
Siglecs are immunomodulatory receptors that regulate immune cell function. A fundamental challenge in studying Siglec-ligand interactions is the low affinity of Siglecs for their ligands. Inspired by ...
www.biorxiv.org
June 14, 2025 at 9:05 PM
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New work on the structure of Siglec-10. Great collaboration that was solidified with a visit to Spain last year with fantastic discussions with June Ereno-Orbea and Jesus Jimenez-Barbero. Nice contributions on modeling by @elisafadda.bsky.social.
www.biorxiv.org/content/10.1...
The unique molecular recognition features of Siglec-10: structural insights into sialoglycan and antibody interactions
Siglec-10 is a sialic acid-binding immunoglobulin-like lectin implicated in immune regulation, yet its molecular basis for ligand recognition and functional role in immune modulation remain poorly def...
www.biorxiv.org
June 12, 2025 at 1:26 PM
Reposted
THE EDMONTON OILERS HAVE MADE IT BACK TO THE STANLEY CUP FINAL 🏆
May 30, 2025 at 2:44 AM
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Voting on ratification of the tentative agreement is open for all NASA members until Thursday, May 8 at noon. Members should check their email for voting information. If you have any questions or issues, please contact the NASA office.
May 6, 2025 at 2:51 PM
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Scientists should try to repeat more studies, but not those looking for a link between vaccines with autism

- the replication studies were done and found that there is, in fact, no link between vaccines and autism.

theconversation.com/scientists-s...
Scientists should try to repeat more studies, but not those looking for a link between vaccines with autism
Funding replicating research is important, but only when allocated well.
theconversation.com
April 7, 2025 at 10:26 PM
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Snap election called, as Carney hopes to leverage leadership momentum amid trade war with U.S.
www.ctvnews.ca/federal-elec...
Snap election called, as Carney hopes to leverage leadership momentum amid trade war with U.S.
Prime Minister Mark Carney has called the 2025 federal election, sending the country into an early campaign, six months ahead of the fixed date.
www.ctvnews.ca
March 23, 2025 at 4:45 PM
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#Octopus
They are masters of underwater escape and camouflage.
March 15, 2025 at 10:47 PM
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I had an excellent call with President von der Leyen about the road ahead for Canada-E.U. trade.

Canada and Europe are strong, reliable partners. In a shifting global economy, that matters more than ever. We’re ready to secure new transatlantic business opportunities together.
March 16, 2025 at 7:10 PM
Mark Carney is elected as the next Liberal party leader and won over 85% of the party votes cast!
March 9, 2025 at 10:39 PM
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‘These tariffs are unjustified’: Smith stands with Trudeau amid U.S. trade war
www.ctvnews.ca/edmonton/art...
‘These tariffs are unjustified’: Smith stands with Trudeau amid U.S. trade war
Premiers across the country, including Danielle Smith, are standing united against U.S. President Donald Trump as the country wakes up to a trade war.
www.ctvnews.ca
March 4, 2025 at 6:58 PM
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Yep, measles is preventable
March 4, 2025 at 2:22 AM
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From our friends at The Associated Press...
Connor McDavid scores in OT to give Canada 3-2 win over U.S. in 4 Nations Face-Off final
www.ctvnews.ca/sports/artic...
Connor McDavid scores in OT to give Canada 3-2 win over U.S. in 4 Nations Face-Off final
Connor McDavid scored at 8:18 of overtime in the 4 Nations Face-Off championship game to give Canada a 3-2 victory over the United States on Thursday night as the North American rivals turned the last...
www.ctvnews.ca
February 21, 2025 at 5:01 AM
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Report: CANADA! CANADA! CANADA! CANADA! CANADA! CANADA!
February 21, 2025 at 4:43 AM
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25 students' associations have sent an open letter to the Alberta government urging it to "restore operating grant funding for the province's public and nonprofit post-secondary institutions (PSIs)."
You can read the full letter at
gsa-ualberta.ca/albertas-pos...
#ableg #abpoli #abpse
Government of Alberta, You Can't Keep Cutting Class - Graduate Student's Association | University of Alberta
Today, we twenty-five students' associations of Alberta urge you to restore operating grant funding for the province's public and nonprofit post-secondary
gsa-ualberta.ca
February 12, 2025 at 9:37 PM
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We have a postdoctoral position open to help lead our CD33 project in microglia. Would be grateful if you could spread the word: macauleylab.ca/job-opening-...
Job Opening – A Postdoctoral fellow or Research Associate – Macauley Lab
macauleylab.ca
February 4, 2025 at 3:00 PM