Luisi-Lab
@luisilab.bsky.social
Research group of Organic Chemistry at the University of Bari. Expertise in: Flow technology, Photocatalysis, Synthetic Methodologies, Green and Sustainable Development.
Visit: https://www.renzoluisi-lab.com/
Visit: https://www.renzoluisi-lab.com/
Iodonitrene-Mediated Nitrogen Transfer to Alkenes for the Direct Synthesis of NH-Aziridines | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/...
Iodonitrene-Mediated Nitrogen Transfer to Alkenes for the Direct Synthesis of NH-Aziridines
This work presents a novel and efficient method for the direct synthesis of NH-aziridines from a broad range of alkenes under mild conditions. The developed method uses aqueous ammonia and (diacetoxyiodo)benzene (PIDA) at 0 °C, offering a straightforward and atom-economical approach. Notably, this approach addresses the common challenge of chemoselectivity, effectively preventing the overoxidation of aziridines to nitriles. Mechanistic studies support the involvement of an in situ-generated iodonitrene as the key nitrogen-transfer intermediate. Overall, this method represents a significant advancement in aziridine synthesis, combining simplicity and selectivity, and complements the existing procedures for the direct NH insertion into alkenes.
pubs.acs.org
September 18, 2025 at 6:55 AM
Iodonitrene-Mediated Nitrogen Transfer to Alkenes for the Direct Synthesis of NH-Aziridines | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/...
Reposted by Luisi-Lab
We’re building the future of pharmaceuticals: connected, intelligent, sustainable. The challenge isn’t to make drugs greener — it’s to redesign the way we make them.
#SusPharma #PharmaInnovation
#SusPharma #PharmaInnovation
August 5, 2025 at 8:45 AM
We’re building the future of pharmaceuticals: connected, intelligent, sustainable. The challenge isn’t to make drugs greener — it’s to redesign the way we make them.
#SusPharma #PharmaInnovation
#SusPharma #PharmaInnovation
Reposted by Luisi-Lab
What happens when design meets catalysis? SusPharma explores additive manufacturing to enable tailor-made, greener reactions.
#SusPharma #3DPrinting #GreenChemistry
#SusPharma #3DPrinting #GreenChemistry
August 8, 2025 at 7:30 AM
What happens when design meets catalysis? SusPharma explores additive manufacturing to enable tailor-made, greener reactions.
#SusPharma #3DPrinting #GreenChemistry
#SusPharma #3DPrinting #GreenChemistry
Reposted by Luisi-Lab
For SusPharma, sustainability is not a single task — it’s the foundation of every process, reaction and solution across the project.
#SustainableByDesign #SusPharma
#SustainableByDesign #SusPharma
August 12, 2025 at 7:30 AM
For SusPharma, sustainability is not a single task — it’s the foundation of every process, reaction and solution across the project.
#SustainableByDesign #SusPharma
#SustainableByDesign #SusPharma
Reposted by Luisi-Lab
Horizon Europe gave us a challenge: make pharma sustainable by design, not as an afterthought.
Sustainability isn’t a feature. It’s the blueprint.
#SusPharma #GreenPharma
Sustainability isn’t a feature. It’s the blueprint.
#SusPharma #GreenPharma
August 16, 2025 at 8:01 AM
Horizon Europe gave us a challenge: make pharma sustainable by design, not as an afterthought.
Sustainability isn’t a feature. It’s the blueprint.
#SusPharma #GreenPharma
Sustainability isn’t a feature. It’s the blueprint.
#SusPharma #GreenPharma
Reposted by Luisi-Lab
Automation isn’t just about efficiency — it’s about safer, smarter, scalable processes.
Robotics is one of SusPharma’s keys to sustainable manufacturing.
#SusPharma #Automation #GreenPharma
Robotics is one of SusPharma’s keys to sustainable manufacturing.
#SusPharma #Automation #GreenPharma
August 18, 2025 at 8:02 AM
Automation isn’t just about efficiency — it’s about safer, smarter, scalable processes.
Robotics is one of SusPharma’s keys to sustainable manufacturing.
#SusPharma #Automation #GreenPharma
Robotics is one of SusPharma’s keys to sustainable manufacturing.
#SusPharma #Automation #GreenPharma
Reposted by Luisi-Lab
Ten partners, ten expertise areas, one shared goal: redesigning pharmaceutical manufacturing for a sustainable future. Each partner leads a critical piece of SusPharma, bringing science, technology and vision together.
#SusPharma #HorizonEurope
#SusPharma #HorizonEurope
August 21, 2025 at 8:02 AM
Ten partners, ten expertise areas, one shared goal: redesigning pharmaceutical manufacturing for a sustainable future. Each partner leads a critical piece of SusPharma, bringing science, technology and vision together.
#SusPharma #HorizonEurope
#SusPharma #HorizonEurope
Reposted by Luisi-Lab
The pharmaceutical industry must cut its carbon footprint without compromising innovation. SusPharma is piloting technologies to make that shift possible.
#SusPharma #HorizonEurope
#SusPharma #HorizonEurope
August 25, 2025 at 8:02 AM
The pharmaceutical industry must cut its carbon footprint without compromising innovation. SusPharma is piloting technologies to make that shift possible.
#SusPharma #HorizonEurope
#SusPharma #HorizonEurope
Reposted by Luisi-Lab
Uniting 10 partners, 30+ researchers, 2 patents & 35+ publications, #SusPharma drives greener & more efficient pharma.
Backed by #HorizonEurope, it links top universities, research centres & companies for a sustainable industry.
🎥 www.youtube.com/watch?v=6ddY...
Backed by #HorizonEurope, it links top universities, research centres & companies for a sustainable industry.
🎥 www.youtube.com/watch?v=6ddY...
SusPharma: shaping a sustainable future for pharmaceuticals
YouTube video by SusPharma
www.youtube.com
August 27, 2025 at 10:00 AM
Uniting 10 partners, 30+ researchers, 2 patents & 35+ publications, #SusPharma drives greener & more efficient pharma.
Backed by #HorizonEurope, it links top universities, research centres & companies for a sustainable industry.
🎥 www.youtube.com/watch?v=6ddY...
Backed by #HorizonEurope, it links top universities, research centres & companies for a sustainable industry.
🎥 www.youtube.com/watch?v=6ddY...
Reposted by Luisi-Lab
In SusPharma, continuous crystallization is more than a technique — it’s a way to make greener processes industrially viable. Scalable, consistent, and sustainable by design.
#FlowChemistry #SusPharma #GreenTech #HorizonEurope
#FlowChemistry #SusPharma #GreenTech #HorizonEurope
August 28, 2025 at 8:02 AM
In SusPharma, continuous crystallization is more than a technique — it’s a way to make greener processes industrially viable. Scalable, consistent, and sustainable by design.
#FlowChemistry #SusPharma #GreenTech #HorizonEurope
#FlowChemistry #SusPharma #GreenTech #HorizonEurope
Generation and Use of Cyclopropenyllithium under Continuous Flow Conditions | Organic Letters pubs.acs.org/doi/10.1021/...
Generation and Use of Cyclopropenyllithium under Continuous Flow Conditions
The cyclopropene scaffold has emerged as a valuable platform in modern synthesis. Here, we present a streamlined flow-based approach for the generation of cyclopropenyllithium and its functionalizatio...
pubs.acs.org
May 22, 2025 at 6:16 AM
Generation and Use of Cyclopropenyllithium under Continuous Flow Conditions | Organic Letters pubs.acs.org/doi/10.1021/...
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April 4, 2025 at 10:46 AM
Ho scoperto 165 utenti Bluesky dalla mia rete sociale usando Sky Follower Bridge.✨
Dai un'occhiata: share.sky-follower-bridge.dev?q=165
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