Simon Little
@littleneuro.bsky.social
Neurologist & Neuroscientist interested in Brain Stimulation, Movement, Mood, Motivation, Sleep, Self Regulation, Psychology and Parenting
Happy to share our latest study led by Tanner Dixon and our team @ucsfhealth.bsky.social and @neurosurgucsf.bsky.social out today in Nature BME! Movement Responsive, AI programmed, BCI-aDBS improves naturalistic movements and reduces excessive movements at rest in PD.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Movement-responsive deep brain stimulation for Parkinson’s disease using a remotely optimized neural decoder - Nature Biomedical Engineering
An adaptive deep brain stimulation algorithm delivers targeted stimulation increases during movement using brain motor signals.
www.nature.com
June 27, 2025 at 5:45 PM
Happy to share our latest study led by Tanner Dixon and our team @ucsfhealth.bsky.social and @neurosurgucsf.bsky.social out today in Nature BME! Movement Responsive, AI programmed, BCI-aDBS improves naturalistic movements and reduces excessive movements at rest in PD.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Simon Little
I'd like to see a revival of panache and artistry in scientific prose style. Since we have to read so many papers, they should be fun and beautiful. I would also argue that this serves the goal of communication: readers will be more likely to remember a striking phrase or image.
March 31, 2025 at 11:07 AM
I'd like to see a revival of panache and artistry in scientific prose style. Since we have to read so many papers, they should be fun and beautiful. I would also argue that this serves the goal of communication: readers will be more likely to remember a striking phrase or image.
Happy to be launching this Special Edition in NPJ Parkinson’s on all things sleep and PD related
January 21, 2025 at 10:14 PM
Happy to be launching this Special Edition in NPJ Parkinson’s on all things sleep and PD related
Reposted by Simon Little
Reposted by Simon Little
This will build on amazing recent work by @melgaby.bsky.social and others, looking at how planning algorithms are encoded in prefrontal cortex circuits: bsky.app/profile/melg...
A bit late to the Bluesky party but here’s our work showing a coordinate system for behavioural space, and an algorithm for computing behavioural sequences in the mFC: www.nature.com/articles/s41...
A cellular basis for mapping behavioural structure - Nature
Mice generalize complex task structures by using neurons in the medial frontal cortex that encode progress to task goals and embed behavioural sequences.
www.nature.com
December 20, 2024 at 12:15 PM
This will build on amazing recent work by @melgaby.bsky.social and others, looking at how planning algorithms are encoded in prefrontal cortex circuits: bsky.app/profile/melg...
Reposted by Simon Little
A study in Nature Medicine finds that deep brain stimulation of a region called the lateral hypothalamus improves walking and promotes recovery in humans and rodents with spinal cord injury. https://go.nature.com/3Vlosyl 🧪
December 2, 2024 at 8:08 PM
A study in Nature Medicine finds that deep brain stimulation of a region called the lateral hypothalamus improves walking and promotes recovery in humans and rodents with spinal cord injury. https://go.nature.com/3Vlosyl 🧪