Thanks to Karel Svoboda for the invitation and for putting together a great symposium!

💡 The future direction of these sensors goes beyond optimization. We want to combine sensor use with technology such as fiber photometry in order to measure the full range of dynamics such as tonic and phasic neuromodulator release.

➡️ Learn more here: www.lintianlab.org/research#tools

🔎 We optimize for signal to noise ratio, measuring intrinsic properties: dynamic range, dissociation constant (Kd), frequency & concentration of signaling molecules.

At a recent lecture I gave at Cold Spring Harbor Lab Asia, I used our calcium indicator as an example to illustrate how we design these sensors.

📈 Optimization is key.

They celebrated with a poster session last week highlighting what they learned. We are so proud of them and their contribution to advancing brain research. Thanks also to their mentors, Yiwei Hua, Julie Chouinard, and Erin Scott!

He introduced the Max Planck Transatlantic Program — focused on strengthening global partnerships, promoting #collaboration at every stage, and investing in the next generation of science.

It was a privilege to be in the room for such an important and timely conversation - curiosity never fades!