Life Metabolism
@lifemetabolism.bsky.social
Science journal concerning all aspects of metabolism
Predictive value of 1-hour postprandial SPARC levels on metabolic outcomes from mediterranean diet adherence: results from a randomized controlled feeding study url: academic.oup.com/lifemeta/art...
November 25, 2025 at 1:05 PM
Predictive value of 1-hour postprandial SPARC levels on metabolic outcomes from mediterranean diet adherence: results from a randomized controlled feeding study url: academic.oup.com/lifemeta/art...
Urate metabolism, in the gut url: academic.oup.com/lifemeta/art...
November 25, 2025 at 1:02 PM
Urate metabolism, in the gut url: academic.oup.com/lifemeta/art...
P5CS-coupled proline metabolism manipulates metabolic dysfunction-associated steatotic liver disease url: academic.oup.com/lifemeta/art...
academic.oup.com
November 25, 2025 at 1:01 PM
P5CS-coupled proline metabolism manipulates metabolic dysfunction-associated steatotic liver disease url: academic.oup.com/lifemeta/art...
miR-378 as a metabolic-state-dependent switch controling liver autophagy and fat accumulation | EurekAlert! www.eurekalert.org/news-release...
miR-378 as a metabolic-state-dependent switch controling liver autophagy and fat accumulation
Emerging evidence reveals that dysregulated autophagy, particularly the selective degradation of lipid droplets (lipophagy), is crucial to maintaining hepatic lipid balance, yet how its activity is re...
www.eurekalert.org
November 19, 2025 at 12:09 PM
miR-378 as a metabolic-state-dependent switch controling liver autophagy and fat accumulation | EurekAlert! www.eurekalert.org/news-release...
Propionic acid secreted by Akkermansia muciniphila alleviates hepatic fibrosis by antioxidant regulation across the gut−liver axis url: academic.oup.com/lifemeta/art...
Propionic acid secreted by Akkermansia muciniphila alleviates hepatic fibrosis by antioxidant regulation across the gut−liver axis
Abstract. The gut commensal bacterium Akkermansia muciniphila (AKK) has emerged as a candidate for treating liver disorders, yet its therapeutic potential
academic.oup.com
November 13, 2025 at 11:20 AM
Propionic acid secreted by Akkermansia muciniphila alleviates hepatic fibrosis by antioxidant regulation across the gut−liver axis url: academic.oup.com/lifemeta/art...
Loss of liver GH signaling causes lean fatty liver | EurekAlert! www.eurekalert.org/news-release...
Loss of liver GH signaling causes lean fatty liver
A recent study published in Life Metabolism by Wu et al. from Dalian Medical University addresses this knowledge gap. The researchers developed a liver-specific Ghr knockout (...
www.eurekalert.org
November 13, 2025 at 11:19 AM
Loss of liver GH signaling causes lean fatty liver | EurekAlert! www.eurekalert.org/news-release...
Aberrant miR-378 expression promotes hepatic lipid accumulation via hijacking the bile acid-regulated autophagy url: academic.oup.com/lifemeta/art...
Aberrant miR-378 expression promotes hepatic lipid accumulation via hijacking the bile acid-regulated autophagy
Abstract. Dysregulated autophagy contributes to liver steatosis, yet its regulation under distinct metabolic contexts remains poorly defined. Here, we iden
academic.oup.com
November 12, 2025 at 2:00 PM
Aberrant miR-378 expression promotes hepatic lipid accumulation via hijacking the bile acid-regulated autophagy url: academic.oup.com/lifemeta/art...
Deletion of hepatic growth hormone receptor contributes to the pathogenesis of lean MAFLD by elevating CD36 url: academic.oup.com/lifemeta/art...
Deletion of hepatic growth hormone receptor contributes to the pathogenesis of lean MAFLD by elevating CD36
Abstract. Metabolic dysfunction-associated fatty liver disease (MAFLD) has become the most prevalent chronic liver disease worldwide, affecting both obese
academic.oup.com
October 31, 2025 at 1:58 AM
Deletion of hepatic growth hormone receptor contributes to the pathogenesis of lean MAFLD by elevating CD36 url: academic.oup.com/lifemeta/art...
A newly identified reductive uric acid pathway offers hope for gout | EurekAlert! www.eurekalert.org/news-release...
A newly identified reductive uric acid pathway offers hope for gout
A new study published in Life Metabolism reports an alternative “reductive pathway” that functions without oxygen. In this route, uric acid is first reduced to a newly identified meta...
www.eurekalert.org
September 9, 2025 at 12:20 AM
A newly identified reductive uric acid pathway offers hope for gout | EurekAlert! www.eurekalert.org/news-release...
Well Met: RIPK1 senses S-adenosyl methionine to ensure cell survival url: academic.oup.com/lifemeta/art...
September 4, 2025 at 2:22 AM
Well Met: RIPK1 senses S-adenosyl methionine to ensure cell survival url: academic.oup.com/lifemeta/art...
Review article by Dr. Lauren Palluth, Prof. Joseph S Takahashi and Prof. Carla B Green: Keeping up with the nicotinamides: NADP(H), the forgotten circadian cofactor that keeps metabolic time url: academic.oup.com/lifemeta/art...
September 2, 2025 at 3:44 PM
Review article by Dr. Lauren Palluth, Prof. Joseph S Takahashi and Prof. Carla B Green: Keeping up with the nicotinamides: NADP(H), the forgotten circadian cofactor that keeps metabolic time url: academic.oup.com/lifemeta/art...
The 13th Xiamen Winter Symposium on Lipid Metabolism and Physiology
January 15-18, 2026
Learn more: xws.xmu.edu.cn
January 15-18, 2026
Learn more: xws.xmu.edu.cn
September 2, 2025 at 3:32 PM
The 13th Xiamen Winter Symposium on Lipid Metabolism and Physiology
January 15-18, 2026
Learn more: xws.xmu.edu.cn
January 15-18, 2026
Learn more: xws.xmu.edu.cn
Weight loss benefits of Tirzepatide persist after stopping treatment in Chinese adults | EurekAlert! www.eurekalert.org/news-release...
Weight loss benefits of Tirzepatide persist after stopping treatment in Chinese adults
In a recent study published in Life Metabolism, researchers at Fudan University report that even after stopping the anti-obesity drug tirzepatide, Chinese obese individuals can maintain significant we...
www.eurekalert.org
July 23, 2025 at 1:28 PM
Weight loss benefits of Tirzepatide persist after stopping treatment in Chinese adults | EurekAlert! www.eurekalert.org/news-release...
Energy stress-induced PKCζ S-glutathionylation is essential for LKB1 cytoplasmic translocation and AMPK activation url: academic.oup.com/lifemeta/art...
Energy stress-induced PKCζ S-glutathionylation is essential for LKB1 cytoplasmic translocation and AMPK activation
Abstract. Energy stress triggers the activation of AMP-activated protein kinase (AMPK) via phosphorylation mediated by liver kinase B1 (LKB1). A pivotal st
academic.oup.com
July 17, 2025 at 3:10 PM
Energy stress-induced PKCζ S-glutathionylation is essential for LKB1 cytoplasmic translocation and AMPK activation url: academic.oup.com/lifemeta/art...
brown fat-enriched exosomal miR-206-3p attenuates hepatic lipogenesis by decreasing pentose phosphate pathway url: academic.oup.com/lifemeta/art...
The brown fat-enriched exosomal miR-206-3p attenuates hepatic lipogenesis by decreasing pentose phosphate pathway
Abstract. Brown adipose tissue (BAT) orchestrates interorgan crosstalk through secreted mediators, including proteins, lipids, and exosomal microRNAs (miRN
academic.oup.com
July 14, 2025 at 1:56 PM
brown fat-enriched exosomal miR-206-3p attenuates hepatic lipogenesis by decreasing pentose phosphate pathway url: academic.oup.com/lifemeta/art...
Weight loss maintenance after tirzepatide cessation in people with overweight/obesity: a real-world follow-up of the phase 3 SURMOUNT-CN trial url: academic.oup.com/lifemeta/art...
Weight loss maintenance after tirzepatide cessation in people with overweight/obesity: a real-world follow-up of the phase 3 SURMOUNT-CN trial
Abstract. Tirzepatide, a dual GIP/GLP-1 receptor agonist, has shown unprecedented efficacy in weight loss and improving metabolic parameters in clinical tr
academic.oup.com
July 1, 2025 at 4:00 PM
Weight loss maintenance after tirzepatide cessation in people with overweight/obesity: a real-world follow-up of the phase 3 SURMOUNT-CN trial url: academic.oup.com/lifemeta/art...
RME-1-associated recycling endosomes participate in vitellogenin secretion in Caenorhabditis elegans url: academic.oup.com/lifemeta/art...
RME-1-associated recycling endosomes participate in vitellogenin secretion in Caenorhabditis elegans
Abstract. Vitellogenins (VITs), the lipoprotein precursors of yolk proteins in Caenorhabditis elegans, are expressed in the intestine, secreted into the ps
academic.oup.com
July 1, 2025 at 3:49 PM
RME-1-associated recycling endosomes participate in vitellogenin secretion in Caenorhabditis elegans url: academic.oup.com/lifemeta/art...
Research Highlight: MDVs bridge metabolite signals to mitochondrial fitness url:https://academic.oup.com/lifemeta/article/doi/10.1093/lifemeta/loaf022/8158082
June 10, 2025 at 3:04 PM
Research Highlight: MDVs bridge metabolite signals to mitochondrial fitness url:https://academic.oup.com/lifemeta/article/doi/10.1093/lifemeta/loaf022/8158082
Building the adipose atlas: consensus guidelines and a standardized analytical workflow url:https://academic.oup.com/lifemeta/article/doi/10.1093/lifemeta/loaf020/8158406
June 10, 2025 at 2:57 PM
Building the adipose atlas: consensus guidelines and a standardized analytical workflow url:https://academic.oup.com/lifemeta/article/doi/10.1093/lifemeta/loaf020/8158406
Combination of time-restricted feeding with resistance exercise ameliorates MAFLD and improves glycemic homeostasis in obese mice url:https://academic.oup.com/lifemeta/article/doi/10.1093/lifemeta/loaf023/8159207
June 10, 2025 at 2:52 PM
Combination of time-restricted feeding with resistance exercise ameliorates MAFLD and improves glycemic homeostasis in obese mice url:https://academic.oup.com/lifemeta/article/doi/10.1093/lifemeta/loaf023/8159207
