Liam Browne
@liamebrowne.bsky.social
Associate Professor at UCL. Systems Neuroscience, Pain, Damage. Views are my own.
Pinned
Liam Browne
@liamebrowne.bsky.social
· Apr 15
Precision cutaneous stimulation in freely moving mice
elifesciences.org
We've developed a way to remotely and precisely activate skin sensory neurons in mice as they naturally explore and navigate their environment - opening doors for studying sensation, behaviour, and pain in naturalistic settings.
Now out: shorturl.at/ry4s9
#neuroskyence #neuroscience #PainResearch
Now out: shorturl.at/ry4s9
#neuroskyence #neuroscience #PainResearch
Reposted by Liam Browne
Our lab is looking for a postdoc! We have interesting projects and cutting-edge techniques such as Neuropixels Opto, Light Beads Microscopy and more. We would be delighted to receive your application. Deadline is 25 November 2025. More info here:
www.ucl.ac.uk/cortexlab/po...
www.ucl.ac.uk/cortexlab/po...
November 12, 2025 at 3:41 PM
Our lab is looking for a postdoc! We have interesting projects and cutting-edge techniques such as Neuropixels Opto, Light Beads Microscopy and more. We would be delighted to receive your application. Deadline is 25 November 2025. More info here:
www.ucl.ac.uk/cortexlab/po...
www.ucl.ac.uk/cortexlab/po...
Reposted by Liam Browne
🚨 Please RT!
We’re recruiting a motivated postdoc to dissect the neurocircuits of affective pain.
Expertise in behavioral models of pain/SUDs, stereotaxy, microscopy, opto/chemogenetics, or fiber photometry encouraged.
Apply 👉 recruit.apo.ucla.edu/JPF10647
#Neuroscience #Postdoc
We’re recruiting a motivated postdoc to dissect the neurocircuits of affective pain.
Expertise in behavioral models of pain/SUDs, stereotaxy, microscopy, opto/chemogenetics, or fiber photometry encouraged.
Apply 👉 recruit.apo.ucla.edu/JPF10647
#Neuroscience #Postdoc
Postdoctoral Research Position
University of California, Los Angeles is hiring. Apply now!
recruit.apo.ucla.edu
October 21, 2025 at 11:44 PM
🚨 Please RT!
We’re recruiting a motivated postdoc to dissect the neurocircuits of affective pain.
Expertise in behavioral models of pain/SUDs, stereotaxy, microscopy, opto/chemogenetics, or fiber photometry encouraged.
Apply 👉 recruit.apo.ucla.edu/JPF10647
#Neuroscience #Postdoc
We’re recruiting a motivated postdoc to dissect the neurocircuits of affective pain.
Expertise in behavioral models of pain/SUDs, stereotaxy, microscopy, opto/chemogenetics, or fiber photometry encouraged.
Apply 👉 recruit.apo.ucla.edu/JPF10647
#Neuroscience #Postdoc
Reposted by Liam Browne
During these uncertain times, I’m very happy to see that my institution, @scripps.edu has an open tenure-track Assistant Professor position. Any field in Chemistry or Biology is welcome. I’d especially love to see fellow neuroscientists apply. Please repost!
apply.interfolio.com/174756
apply.interfolio.com/174756
Apply - Interfolio
{{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
October 14, 2025 at 5:35 PM
During these uncertain times, I’m very happy to see that my institution, @scripps.edu has an open tenure-track Assistant Professor position. Any field in Chemistry or Biology is welcome. I’d especially love to see fellow neuroscientists apply. Please repost!
apply.interfolio.com/174756
apply.interfolio.com/174756
Reposted by Liam Browne
If evolution, comparative #neuroskyence & #PainResearch are your thing, here's a great review from Terry Walters: journals.biologists.com/jeb/article/...
From nociception in aneural animals to human suffering: toward a comparative biology of pain
Summary: The biology of widely shared and unusual features of human pain is informed by functional and mechanistic comparisons of nociception and pain-like aversive states across vertebrate and invert...
journals.biologists.com
October 14, 2025 at 7:06 AM
If evolution, comparative #neuroskyence & #PainResearch are your thing, here's a great review from Terry Walters: journals.biologists.com/jeb/article/...
Reposted by Liam Browne
One week left to apply!
Please RT
2 new positions in the lab as postdoc & PhD!
Interested in stress, pain, or reward? This project has it all!
We are a friendly but ambitious group. Oslo is a capital city on the fjord & bordered by forest, great urban & outdoors opportunities: 💃 ⛷️ 🚣 🎭 🎶
www.jobbnorge.no/en/available...
2 new positions in the lab as postdoc & PhD!
Interested in stress, pain, or reward? This project has it all!
We are a friendly but ambitious group. Oslo is a capital city on the fjord & bordered by forest, great urban & outdoors opportunities: 💃 ⛷️ 🚣 🎭 🎶
www.jobbnorge.no/en/available...
Postdoctoral Research Fellowship (286516) | University of Oslo
Job title: Postdoctoral Research Fellowship (286516), Employer: University of Oslo, Deadline: Wednesday, October 15, 2025
www.jobbnorge.no
October 7, 2025 at 7:36 AM
One week left to apply!
Reposted by Liam Browne
Lots of exciting clinical PhD projects at Crick - including the opportunity for neurosurgeons to work with us and record electrical activity in patients with neuropixels probes. Please share widely!
We're looking for clinicians who are passionate about research to join our 3-year fully funded clinical PhD programme. 🔬🩺
Apply by 14 November 2025. 👇
www.crick.ac.uk/careers-stud...
Apply by 14 November 2025. 👇
www.crick.ac.uk/careers-stud...
Doctoral clinical fellows
The Crick's clinical PhD programme.
www.crick.ac.uk
October 1, 2025 at 10:08 AM
Lots of exciting clinical PhD projects at Crick - including the opportunity for neurosurgeons to work with us and record electrical activity in patients with neuropixels probes. Please share widely!
Reposted by Liam Browne
We are proud to launch what we think is going to be fantastic opportunity for pain neuroscientists and clinicians to learn the foundations of pain neuroscience
September is #PainAwarenessMonth, and we are excited to be launching our brand-new MSc in Pain Neurosciences. Could you help shape the future of #pain research? Opening soon for 2026 admissions 👀
Learn more 👇
bit.ly/OxMScPain
Learn more 👇
bit.ly/OxMScPain
October 1, 2025 at 5:55 AM
We are proud to launch what we think is going to be fantastic opportunity for pain neuroscientists and clinicians to learn the foundations of pain neuroscience
Reposted by Liam Browne
New preprint out from the lab. We identified three critical windows over which sensorimotor behaviours can be shaped. Altered early experience over these windows changes somatosensory and motor outcomes for life. Tour de force experiments by Laura Andreoli. @medresfdn.bsky.social @uclnpp.bsky.social
Discrete and sequential critical periods organise the development of task-specific sensorimotor circuits in mice https://www.biorxiv.org/content/10.1101/2025.09.18.676788v1
September 19, 2025 at 10:44 AM
New preprint out from the lab. We identified three critical windows over which sensorimotor behaviours can be shaped. Altered early experience over these windows changes somatosensory and motor outcomes for life. Tour de force experiments by Laura Andreoli. @medresfdn.bsky.social @uclnpp.bsky.social
Reposted by Liam Browne
We're looking for a senior project coordinator in Oxford - apply by friday eng.ox.ac.uk/jobs/job-det...
Job Detail
eng.ox.ac.uk
September 1, 2025 at 9:32 AM
We're looking for a senior project coordinator in Oxford - apply by friday eng.ox.ac.uk/jobs/job-det...
Reposted by Liam Browne
We've found a new gene linked to chronic pain in humans! The gene SLC45A4 encodes (the long-awaited) neuronal polyamine transporter, which is important for pain signalling in nerves. We hope this discovery might lead to new chronic pain treatments in the future!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
SLC45A4 is a pain gene encoding a neuronal polyamine transporter - Nature
The SLC45A4 gene encodes a neuronal polyamine transporter and is linked to pain response in humans and mice.
www.nature.com
August 21, 2025 at 12:16 PM
We've found a new gene linked to chronic pain in humans! The gene SLC45A4 encodes (the long-awaited) neuronal polyamine transporter, which is important for pain signalling in nerves. We hope this discovery might lead to new chronic pain treatments in the future!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Liam Browne
We are super excited about the first human transcranial ultrasound study from our lab which is now on BiorXiv, showing the amygdala‘s role in processing ambiguous emotions and showing TUS changed resting-state connectivity and metabolite concentrations (GABA) in the amygdala - a huge team effort! 🥳🙏🏼
Very happy to share my first preprint from @oxexppsy.bsky.social @oxneuro.bsky.social ! We (me + co-first authors @lilweb.bsky.social @mirunarascu.bsky.social + PI @mkflugge.bsky.social + many others) used transcranial focused ultrasound stimulation (TUS/tFUS/LIFU) of the human amygdala ... (1/15)
August 20, 2025 at 6:45 AM
We are super excited about the first human transcranial ultrasound study from our lab which is now on BiorXiv, showing the amygdala‘s role in processing ambiguous emotions and showing TUS changed resting-state connectivity and metabolite concentrations (GABA) in the amygdala - a huge team effort! 🥳🙏🏼
Reposted by Liam Browne
1/3) This may be a very important paper, it suggests that there are no prediction error encoding neurons in sensory areas of cortex:
www.biorxiv.org/content/10.1...
I personally am a big fan of the idea that cortical regions (allo and neo) are doing sequence prediction.
But...
🧠📈 🧪
www.biorxiv.org/content/10.1...
I personally am a big fan of the idea that cortical regions (allo and neo) are doing sequence prediction.
But...
🧠📈 🧪
Sensory responses of visual cortical neurons are not prediction errors
Predictive coding is theorized to be a ubiquitous cortical process to explain sensory responses. It asserts that the brain continuously predicts sensory information and imposes those predictions on lo...
www.biorxiv.org
July 11, 2025 at 3:45 PM
1/3) This may be a very important paper, it suggests that there are no prediction error encoding neurons in sensory areas of cortex:
www.biorxiv.org/content/10.1...
I personally am a big fan of the idea that cortical regions (allo and neo) are doing sequence prediction.
But...
🧠📈 🧪
www.biorxiv.org/content/10.1...
I personally am a big fan of the idea that cortical regions (allo and neo) are doing sequence prediction.
But...
🧠📈 🧪
Reposted by Liam Browne
Calling all neuroscience postdocs!
Come and share your work with the London neuroscience community. No CVs, publication records or recommendation letters needed.
Learn more about SWC’s Emerging Neuroscientists Seminar Series and apply by 10 July:
www.sainsburywellcome.org/web/content/...
Come and share your work with the London neuroscience community. No CVs, publication records or recommendation letters needed.
Learn more about SWC’s Emerging Neuroscientists Seminar Series and apply by 10 July:
www.sainsburywellcome.org/web/content/...
June 5, 2025 at 7:48 AM
Calling all neuroscience postdocs!
Come and share your work with the London neuroscience community. No CVs, publication records or recommendation letters needed.
Learn more about SWC’s Emerging Neuroscientists Seminar Series and apply by 10 July:
www.sainsburywellcome.org/web/content/...
Come and share your work with the London neuroscience community. No CVs, publication records or recommendation letters needed.
Learn more about SWC’s Emerging Neuroscientists Seminar Series and apply by 10 July:
www.sainsburywellcome.org/web/content/...
Reposted by Liam Browne
Excited to present our study in @natneuro.nature.com: a deep brain pathway that triggers safety-driven movement—overriding needs like finding food or social contacts. A look into how the brain weighs deep instincts. Congrats to all and first author @nkrauth.bsky.social. shorturl.at/toYFN
A hypothalamus–brainstem circuit governs the prioritization of safety over essential needs - Nature Neuroscience
Animals need to adapt behavior to balance survival with fulfillment of essential needs. Krauth et al. identify neurons in the lateral hypothalamus that, when activated, prioritize survival over other ...
shorturl.at
May 28, 2025 at 11:52 AM
Excited to present our study in @natneuro.nature.com: a deep brain pathway that triggers safety-driven movement—overriding needs like finding food or social contacts. A look into how the brain weighs deep instincts. Congrats to all and first author @nkrauth.bsky.social. shorturl.at/toYFN
Reposted by Liam Browne
🧠 🍄 ⚡️🐭
Now published in @natneuro.nature.com
Psilocybin enhances fear extinction by reshaping retrosplenial cortex ensembles—suppressing fear neurons, recruiting extinction neurons + boosting plasticity to enable behavioral flexibility
nature.com/articles/s4159…
Now published in @natneuro.nature.com
Psilocybin enhances fear extinction by reshaping retrosplenial cortex ensembles—suppressing fear neurons, recruiting extinction neurons + boosting plasticity to enable behavioral flexibility
nature.com/articles/s4159…
May 26, 2025 at 1:36 PM
🧠 🍄 ⚡️🐭
Now published in @natneuro.nature.com
Psilocybin enhances fear extinction by reshaping retrosplenial cortex ensembles—suppressing fear neurons, recruiting extinction neurons + boosting plasticity to enable behavioral flexibility
nature.com/articles/s4159…
Now published in @natneuro.nature.com
Psilocybin enhances fear extinction by reshaping retrosplenial cortex ensembles—suppressing fear neurons, recruiting extinction neurons + boosting plasticity to enable behavioral flexibility
nature.com/articles/s4159…
Reposted by Liam Browne
Maps are everywhere in the brain...and finally we've discovered one in the nose! Led by @davidhbrann.bsky.social, we uncovered the logic that specifies the positions of each of the 1,000 sensory neuron subtypes in the nose and aligns their projections to the brain.👇👃see more details below👃👇
A spatial code governs olfactory receptor choice and aligns sensory maps in the nose and brain
Although topographical maps organize many peripheral sensory systems, it remains unclear whether olfactory sensory neurons (OSNs) choose which of the ~1100 odor receptors (ORs) to express based upon t...
www.biorxiv.org
May 9, 2025 at 8:44 PM
Maps are everywhere in the brain...and finally we've discovered one in the nose! Led by @davidhbrann.bsky.social, we uncovered the logic that specifies the positions of each of the 1,000 sensory neuron subtypes in the nose and aligns their projections to the brain.👇👃see more details below👃👇
Reposted by Liam Browne
Linking function and structure at scale with X-rays - and several times over. Massive congratulations to the team @yuxinzhang.bsky.social, @carlesbosch.bsky.social, @apacureanu.bsky.social @esrf.fr, @crick.ac.uk and all our collaborators.
My PhD project is out as a preprint!
We combined 2P and synchrotron X-ray to understand mouse olfactory bulb circuits, linking physiology to structure in 3 animals!
doi.org/10.1101/2025...
🙌 @carlesbosch.bsky.social, @apacureanu.bsky.social, @andreas-t-schaefer.bsky.social, @esrf.fr, @crick.ac.uk
We combined 2P and synchrotron X-ray to understand mouse olfactory bulb circuits, linking physiology to structure in 3 animals!
doi.org/10.1101/2025...
🙌 @carlesbosch.bsky.social, @apacureanu.bsky.social, @andreas-t-schaefer.bsky.social, @esrf.fr, @crick.ac.uk
May 1, 2025 at 12:24 PM
Linking function and structure at scale with X-rays - and several times over. Massive congratulations to the team @yuxinzhang.bsky.social, @carlesbosch.bsky.social, @apacureanu.bsky.social @esrf.fr, @crick.ac.uk and all our collaborators.
We've developed a way to remotely and precisely activate skin sensory neurons in mice as they naturally explore and navigate their environment - opening doors for studying sensation, behaviour, and pain in naturalistic settings.
Now out: shorturl.at/ry4s9
#neuroskyence #neuroscience #PainResearch
Now out: shorturl.at/ry4s9
#neuroskyence #neuroscience #PainResearch
Precision cutaneous stimulation in freely moving mice
elifesciences.org
April 15, 2025 at 10:49 AM
We've developed a way to remotely and precisely activate skin sensory neurons in mice as they naturally explore and navigate their environment - opening doors for studying sensation, behaviour, and pain in naturalistic settings.
Now out: shorturl.at/ry4s9
#neuroskyence #neuroscience #PainResearch
Now out: shorturl.at/ry4s9
#neuroskyence #neuroscience #PainResearch
Reposted by Liam Browne
2. Systems Neuroscience PhD position, supervised jointly with Sarah Ruediger @ruedigersarah.bsky.social
This is to investigate the differential circuits involved in habitual and goal-directed behaviours.
www.findaphd.com/phds/project...
This is to investigate the differential circuits involved in habitual and goal-directed behaviours.
www.findaphd.com/phds/project...
Systems Neuroscience PhD at UCL at University College London on FindAPhD.com
PhD Project - Systems Neuroscience PhD at UCL at University College London, listed on FindAPhD.com
www.findaphd.com
April 14, 2025 at 10:24 AM
2. Systems Neuroscience PhD position, supervised jointly with Sarah Ruediger @ruedigersarah.bsky.social
This is to investigate the differential circuits involved in habitual and goal-directed behaviours.
www.findaphd.com/phds/project...
This is to investigate the differential circuits involved in habitual and goal-directed behaviours.
www.findaphd.com/phds/project...
Reposted by Liam Browne
1. Project on Computational Neuroscience / NeuroAI PhD, supervised jointly with Caswell Barry @caswell.bsky.social
Here we want to build NeuroAI models that transform visual information to spatial navigation information.
www.findaphd.com/phds/project...
Here we want to build NeuroAI models that transform visual information to spatial navigation information.
www.findaphd.com/phds/project...
Computational Neuroscience, NeuroAI PhD at UCL at University College London on FindAPhD.com
PhD Project - Computational Neuroscience, NeuroAI PhD at UCL at University College London, listed on FindAPhD.com
www.findaphd.com
April 14, 2025 at 10:24 AM
1. Project on Computational Neuroscience / NeuroAI PhD, supervised jointly with Caswell Barry @caswell.bsky.social
Here we want to build NeuroAI models that transform visual information to spatial navigation information.
www.findaphd.com/phds/project...
Here we want to build NeuroAI models that transform visual information to spatial navigation information.
www.findaphd.com/phds/project...
Reposted by Liam Browne
New preprint ✍️🚨
✨Ontogeny of tactile, vocal and kinship dynamics in rat pup huddling
-Huddle dynamics develop w/o kinship selectivity
-Vocal/internal-state quiets w/ huddling & kin/ touch in yng pups
tinyurl.com/y7vhkwjc
👏 @flor-bela.bsky.social @hughtakemoto.bsky.social @kinshiplab.bsky.social
✨Ontogeny of tactile, vocal and kinship dynamics in rat pup huddling
-Huddle dynamics develop w/o kinship selectivity
-Vocal/internal-state quiets w/ huddling & kin/ touch in yng pups
tinyurl.com/y7vhkwjc
👏 @flor-bela.bsky.social @hughtakemoto.bsky.social @kinshiplab.bsky.social
April 9, 2025 at 9:42 AM
New preprint ✍️🚨
✨Ontogeny of tactile, vocal and kinship dynamics in rat pup huddling
-Huddle dynamics develop w/o kinship selectivity
-Vocal/internal-state quiets w/ huddling & kin/ touch in yng pups
tinyurl.com/y7vhkwjc
👏 @flor-bela.bsky.social @hughtakemoto.bsky.social @kinshiplab.bsky.social
✨Ontogeny of tactile, vocal and kinship dynamics in rat pup huddling
-Huddle dynamics develop w/o kinship selectivity
-Vocal/internal-state quiets w/ huddling & kin/ touch in yng pups
tinyurl.com/y7vhkwjc
👏 @flor-bela.bsky.social @hughtakemoto.bsky.social @kinshiplab.bsky.social
Reposted by Liam Browne
Last few days to apply to come work with our team- deadline 11th April. See details below.
Come join our lab as Postdoctoral Fellow! The project will investigate the maturation of spinal circuits and their plasticity within chronic widespread pain states.
Apply here: www.ucl.ac.uk/work-at-ucl/... until 11th April.
@ucllifesciences.bsky.social @uclnpp.bsky.social @jobrxiv.bsky.social
Apply here: www.ucl.ac.uk/work-at-ucl/... until 11th April.
@ucllifesciences.bsky.social @uclnpp.bsky.social @jobrxiv.bsky.social
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
www.ucl.ac.uk
April 8, 2025 at 3:54 PM
Last few days to apply to come work with our team- deadline 11th April. See details below.
Reposted by Liam Browne
New preprint out! We developed a behavioural platform for the kinematic analysis of skilled whole body behaviour. Very fun collaboration with Christopher Black, @liamebrowne.bsky.social and Rob Brownstone.
Ethologically relevant behavioural assay for investigating reach and grasp kinematics during whole-body motor control in mice https://www.biorxiv.org/content/10.1101/2025.04.04.647225v1
April 6, 2025 at 1:59 PM
New preprint out! We developed a behavioural platform for the kinematic analysis of skilled whole body behaviour. Very fun collaboration with Christopher Black, @liamebrowne.bsky.social and Rob Brownstone.
Reposted by Liam Browne
How is the input of the different kinds of primary sensory neurons responding to heat and mechanical stimuli summarized in the spinal cord? Check out our recent study.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Neural ensembles that encode nocifensive mechanical and heat pain in mouse spinal cord - Nature Neuroscience
Zhang et al. identify unimodal neural representations in the spinal cord of cutaneous mechanical and heat stimuli gated by a shared feed-forward local inhibitory neuron type and a neural transition du...
www.nature.com
March 24, 2025 at 4:07 PM
How is the input of the different kinds of primary sensory neurons responding to heat and mechanical stimuli summarized in the spinal cord? Check out our recent study.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Liam Browne
Excited to present the latest from the lab out today in Cell www.cell.com/cell/fulltex.... See Thread! 1/8
March 4, 2025 at 4:34 PM
Excited to present the latest from the lab out today in Cell www.cell.com/cell/fulltex.... See Thread! 1/8