"In every living thing there ticks a clock...": @david-farrier.bsky.social superb & unsettling on how "wild clocks"––spruce saplings, oyster colonies, reindeer herds––are falling out of synchronization as the Earth transforms.
It’s becoming harder to keep time.
emergencemagazine.org/essay/wild-c...

A new ITV documentary at the Oxford Vaccine Group, exploring the groups journey over the past three decades and what’s to come in the next 30 years.

It’s nice to showcase some of our preclinical work in the documentary.

www.itv.com/watch/news/o...

Cellular RNAs directly regulate the activity of an antiviral immune signaling complex
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
@science.org @nandangokhale.bsky.social @ramlabuw.bsky.social

Finally! The Hydroxychloroquine study by Gautret et al. has been retracted. I wrote a critical post about it in March 2020, days after it came out.

scienceintegritydigest.com/2020/03/24/t...

📢 Huge News! 📢

The MRC has launched two centres of research excellence to transform gene therapies: IDRM’s Paul Riley will co-direct the MRC/BHF CoRE in Advanced Cardiac Therapies & Stephan Sanders will direct the MRC CoRE in Therapeutic Genomics.
Read more: lnkd.in/g-3CmAsP
#GeneTherapies

My houseplants watching me pour water in the coffee maker

Ever wondered why walking around museums is weirdly tiring? At normal speed our legs act like pendulums, swinging forward from the hip & saving us a huge amount of energy. In "museum shuffle" our muscles must do ALL the work of constant readjustment. So cake in the cafe is scientifically justified 🥳

The December issue of #Science #Immunology is out now! This week: #MAITcell plasticity in #antibacterial immunity; how #inflammatory status of #lung before #COVID19 infection impacts #viral control; & #helminths utilize glutamate dehydrogenase to prevent #AAMs & #TH2 activation!

bit.ly/SI_DEC_24

The next frontier of T cell therapeutics when the T also stands for tissue-targeting, such as brain or local immune response, via synthetic gene circuits
@science.org

science.org/doi/10.1126/...
science.org/doi/10.1126/...
science.org/doi/10.1126/...

#WeekendRead! #LocationLocationLocation! Amazing @Nature by @touficmayassi.bsky.social, Xavier &co showing regional specialization of the gut at the spatial (single cell) level! Strong resilience after inflammation & ILC2 are key in middle colon adaption to microbiota! www.nature.com/articles/s41...

What is optimally growing in OPTI-MEM?

Totally agree! Feels like a new scientific social hub!

I went to a fantastic talk today given by Dr Dalan Bailey from the Pirbright Institute. Fascinating and important ongoing work in predicting the next pandemic pathogen.

A surprise in Oxford this morning #snow #oxford

Question/help needed: FLOWJO analysis better on a windows laptop or MAC? I have 300+ flow cytometry samples acquired on the Cytek Aurora (15 colour panel) and need to analyse without computer crashing 🫣

✍️ Intro post: I’m Lee, a postdoctoral researcher in the Oxford Vaccine Group, at the University of Oxford. My research focuses on pre-clinical vaccine development using viral vector and mRNA vaccines against deadly arenaviruses. Love reading things immunology and physiology!

All aboard BlueSky. Looking forward to sharing in science over here!