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lebektamina.bsky.social
Tamina Lebek
@lebektamina.bsky.social
95 followers 99 following 4 posts
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Reposted by Tamina Lebek
mbadonyi.bsky.social
We’ve updated the acmgscaler manuscript following reviewer and community feedback.

The R package now has a single calibrate() function, and the Colab interface is easier to use.

📄 Manuscript: www.biorxiv.org/content/10.1...
🧪 Colab: edin.ac/4mjzijp

#rstats @theacmg.bsky.social
acmgscaler: An R package and Colab for standardised gene-level variant effect score calibration within the ACMG/AMP framework
A genome-wide variant effect calibration method was recently developed under the guidelines of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology (ACMG/A...
www.biorxiv.org
August 15, 2025 at 8:35 AM
Reposted by Tamina Lebek
cellysally.bsky.social
A small good thing in these difficult times.

The always-impressive Aisling Fairweather treated us to some particularly delicious data in lab meeting today #BakeYourData #NeighbourLabelling
A tasty cheese and veg quiche decorated with a FACS plot. Axis are labelled 530 and 610 using courgettes, the axis are asparagus spears, the data is presented as chopped red pepper (610+ cells) and chopped courgette (530+ cells) and the gate is drawn using rosemary leaves. It is marvellous. The same data is represented ina more conventional format in the adjacent photo. A FACS plot. Axis are labelled 530 and 610 . The data shows that 74.6% of cells are expressing mCherry (610+). The same data is represented in the form of a vegetable quiche in the neighbouring photo.
April 7, 2025 at 1:44 PM
lebektamina.bsky.social
So excited to have been at #biologists100! @biologists.bsky.social very family-friendly as always!
the-node.bsky.social the Node @the-node.bsky.social · Mar 27
Tamina Lebek @lebektamina.bsky.social is a panellist in the last session of #biologists100.

We took a photo of her and her little collaborator! Her key words are #BabiesInScience #PUFFFIN #NeighbourLabelling. Check out this interview with Tamina: thenode.biologists.com/the-sdb-bsdb...
March 27, 2025 at 5:58 PM
Reposted by Tamina Lebek
mbadonyi.bsky.social
1/ Excited to share our latest work on the "Prevalence of loss-of-function, gain-of-function and dominant-negative mechanisms across genetic disease phenotypes". @marshlab.bsky.social @uoe-igc.bsky.social www.biorxiv.org/content/10.1...
Prevalence of loss-of-function, gain-of-function and dominant-negative mechanisms across genetic disease phenotypes
Molecular disease mechanisms caused by mutations in protein-coding regions are diverse, but they can be broadly categorised into loss-of-function (LOF), gain-of-function (GOF), and dominant-negative (...
www.biorxiv.org
March 17, 2025 at 12:44 PM
lebektamina.bsky.social
Honored to be featured in #100biologists alongside so many inspiring scientists! @biologists.bsky.social and @bsdb.bsky.social supported my PhD journey through conferences, seminars, and travel grants. Proud to have two publications in CoB journals and to give back as a BSDB committee member!
biologists.bsky.social The Company of Biologists @biologists.bsky.social · Feb 11
We are featuring Tamina Lebek, @bsdb.bsky.social ECR representative and a PhD student at @edinburgh-uni.bsky.social, as an extraordinary biologist this week. Tamina has also been interviewed by @the-node.bsky.social and given a Development presents…talk.
#100biologists
@lebektamina.bsky.social
The Company of Biologists 100 logo to the left and QR code to the right. Portrait of Tamina Lebek to the left, text to the right 100 extraordinary biologists Tamina Lebek BSDB ECR representative Tamina Lebek has been interviewed by the Node and given a Development presents… talk. Tamina is a PhD student at The University of Edinburgh, UK, and has developed a neighbour-labelling system called PUFFFIN to investigate cell communication. #100biologists #biologists100
February 11, 2025 at 9:57 PM
Reposted by Tamina Lebek
cellysally.bsky.social
How to make labs more sustainable: energy use in labs
www.biologists.com/stories/sust...
How to make labs more sustainable: energy use in labs
13 January 2025 by Jeroen Dobbelaere Within research labs there are several recognisable appliances which use a considerable amount of energy. These appliances include freezers for storing samples, in...
www.biologists.com
January 17, 2025 at 8:36 AM
Reposted by Tamina Lebek
mbadonyi.bsky.social
Happy to see our predictive scores integrated into DECIPHER! We hope they will help clinicians uncover the molecular mechanisms driving dominant disease. Huge thanks to the team at @deciphergenomics.bsky.social for their support. A follow-up study is underway to improve predictions—stay tuned!
deciphergenomics.bsky.social deciphergenomics.bsky.social @deciphergenomics.bsky.social · Jan 8
Protein predictive scores which predict the likelihood that the protein is associated with a dominant-negative, gain-of-function or loss-of-function mechanism are displayed. Curated literature support for a molecular disease mechanism is also shown jmarshlab.bsky.social @mbadonyi.bsky.social
January 8, 2025 at 4:36 PM
Reposted by Tamina Lebek
biologists.bsky.social
The next extraordinary biologist is Anahí Binagui-Casas, an early-career researcher involved in the Biologists @ 100 conference and her research focusses on vertebrate development. #100biologists @abinagui.bsky.social.

Register for the conference at 100yearsconference.biologists.com.
The Company of Biologists 100 logo to the left and QR code to the right. Portrait of Binagui-Casas to the left, text to the right 100 extraordinary biologists Anahí Binagui-Casas Anahí Binagui-Casas is a BSDB early-career representative involved in the Biologists @ 100 conference and a Development Travelling Fellowship awardee. She participated in the 2020 Workshop on human birth defects and investigates vertebrate development at The University of Edinburgh. #100biologists #biologists100
January 8, 2025 at 12:03 PM
Reposted by Tamina Lebek
biologists.bsky.social
🧪The #biologists100 programme includes different scientific tracks. Learn more about each in this thread 🧵.

The conference incorporates the BSCB and BSDB @bsdb.bsky.social Spring Meetings.

View the #CellBio & #DevBio programme and speakers at bit.ly/3B2uflr

📆Abstracts due: 13 December
Biologists @ 100 conference Incorporating the Spring Meetings of the British Society for Cell Biology (BSCB) and the British Society for Developmental Biology (BSDB). Organisers BSCB • Aymen al-Rawi, • Vicky Cowling • Viji Draviam • Jason King • Laura Machesky BSDB • Véronique Azuara • Anahi Binagui-Casas • Shankar Srinivas • Abigail Tucker Speakers on cell and developmental biology • Alexander Aulehla • Margarida Cardoso-Moreira • Alain Chedotal • Jennifer DeLuca • Alba Diz-Munoz • Anja Geitmann • Susana Godinho • Matthias Heinemann • Myriam Hemberger • Maneesha Inamdar • Loydie Jerome-Majewska • Ana-Maria Lennon-Dumenil • Tom MacVicar • Marisa Merino • Michel Milinkovitch • Ewa Paluch • Olivier Pourquie • Jordan Raff • Crystal Rogers • Nicolas Rivron • Victoria Sanz Moreno • Ritwick Sawarkar • Hari Shroff • Benjamin Steventon • Chris Whitewoods • Alpha Yap Register now biologists.com/100-years/conference
December 9, 2024 at 12:32 PM
Reposted by Tamina Lebek
biologists.bsky.social
We are happy to report that our journals and community sites now have Bluesky accounts. Follow them at:
@dev-journal.bsky.social
@jcellsci.bsky.social
@jexpbiol.bsky.social
@dmmjournal.bsky.social
@biologyopen.bsky.social
@the-node.bsky.social
@prelights.bsky.social
@focalplane.bsky.social
November 25, 2024 at 2:44 PM
lebektamina.bsky.social
We had a great time at today's Development presents seminar!
cellysally.bsky.social Sally Lowell @cellysally.bsky.social · Nov 20
I'm so incredibly proud of our PhD student @lebektamina.bsky.social for delivering an excellent DevPres seminar this afternoon in close collaboration with her young baby 😍👶🧪

Read Tamina's work on illuminating cell neighbourhoods and locally-synchronising differentiation:PMID: 38997504
#DevBio
A photograph of my computer screen showing a young woman delivering a seminar. She is showing a slide entitled "A new approach to label, isolate and profile neighbours". She is carrying a small sleeping baby in a sling on her front. Irrelevantly, there is also a very small picture of Adam Ant on the wall behing my computer screen: this is there for a very good reason related to surviving a career in science, which I will reveal on demand.
November 20, 2024 at 4:10 PM
lebektamina.bsky.social
Looking forward to talking about our PUFFFIN project at Development presents! Have a look at our paper now www.embopress.org/doi/full/10.... and tune in tomorrow! #DevBio #PUFFFIN
November 19, 2024 at 3:38 PM