Waser Group
@lcsolab.bsky.social
Organic Chemistry Lab at ISIC EPFL, NCCR Catalysis, SNE ChemBio
https://www.epfl.ch/labs/lcso/ https://www.linkedin.com/in/lcso-lab/
Starter packs - OrgChem https://go.bsky.app/NSEFPFJ https://go.bsky.app/GwH8t
- Chem. in CH https://go.bsky.app/CdvVFKj
https://www.epfl.ch/labs/lcso/ https://www.linkedin.com/in/lcso-lab/
Starter packs - OrgChem https://go.bsky.app/NSEFPFJ https://go.bsky.app/GwH8t
- Chem. in CH https://go.bsky.app/CdvVFKj
Our current view from the lab!
October 28, 2025 at 11:53 AM
Our current view from the lab!
The review of Emma Robert on cycloaddition and annulation reactions with Donor-Acceptor cyclobutanes has now appeared in @helvchimacta.bsky.social !
doi.org/10.1002/hlca...
doi.org/10.1002/hlca...
October 5, 2025 at 2:56 PM
The review of Emma Robert on cycloaddition and annulation reactions with Donor-Acceptor cyclobutanes has now appeared in @helvchimacta.bsky.social !
doi.org/10.1002/hlca...
doi.org/10.1002/hlca...
Current pump vacuo record @lcsolab.bsky.social (with attached Schlenk line)
September 26, 2025 at 3:30 PM
Current pump vacuo record @lcsolab.bsky.social (with attached Schlenk line)
The preprint of the work of Josh Wu, Tobias Milzarek and Matthew Wodrich on the trifluoromethylation of Cyclopropenylbenziodoxoles is now available at ChemRxiv. This method gives access to unique fluorinated building blocks.
chemrxiv.org/engage/chemr...
chemrxiv.org/engage/chemr...
September 1, 2025 at 10:27 AM
The preprint of the work of Josh Wu, Tobias Milzarek and Matthew Wodrich on the trifluoromethylation of Cyclopropenylbenziodoxoles is now available at ChemRxiv. This method gives access to unique fluorinated building blocks.
chemrxiv.org/engage/chemr...
chemrxiv.org/engage/chemr...
Congratulations to Dr. Emma Robert on the successful defense of her PhD! Emma becomes the 32nd PhD graduate from @lcsolab.bsky.social
August 30, 2025 at 6:40 AM
Congratulations to Dr. Emma Robert on the successful defense of her PhD! Emma becomes the 32nd PhD graduate from @lcsolab.bsky.social
From now on until end of September we consider applications to @lcsolab.bsky.social for a regular PhD position starting earliest in September 2026!
For general information, see:
www.epfl.ch/labs/lcso/gr...
For details on the application process, see:
www.epfl.ch/labs/lcso/wp...
For general information, see:
www.epfl.ch/labs/lcso/gr...
For details on the application process, see:
www.epfl.ch/labs/lcso/wp...
August 29, 2025 at 7:22 AM
From now on until end of September we consider applications to @lcsolab.bsky.social for a regular PhD position starting earliest in September 2026!
For general information, see:
www.epfl.ch/labs/lcso/gr...
For details on the application process, see:
www.epfl.ch/labs/lcso/wp...
For general information, see:
www.epfl.ch/labs/lcso/gr...
For details on the application process, see:
www.epfl.ch/labs/lcso/wp...
Interesting preprint from Norihiro Tada and Akichika Itoh and co-workers on the use of diinyl EBX reagents for thiol diinylation:
chemrxiv.org/engage/chemr...
chemrxiv.org/engage/chemr...
August 26, 2025 at 6:36 AM
Interesting preprint from Norihiro Tada and Akichika Itoh and co-workers on the use of diinyl EBX reagents for thiol diinylation:
chemrxiv.org/engage/chemr...
chemrxiv.org/engage/chemr...
Summer update of the research website @lcsolab.bsky.social with improved introduction, addition of the latest progress and a new page dedicated to collaborative works!
www.epfl.ch/labs/lcso/re...
www.epfl.ch/labs/lcso/re...
August 6, 2025 at 4:04 PM
Summer update of the research website @lcsolab.bsky.social with improved introduction, addition of the latest progress and a new page dedicated to collaborative works!
www.epfl.ch/labs/lcso/re...
www.epfl.ch/labs/lcso/re...
Last two organic seminars of the semester with Prof. Mariola Tortosa from UAM and Daniel Werz from the University of Freiburg
July 10, 2025 at 6:11 AM
Last two organic seminars of the semester with Prof. Mariola Tortosa from UAM and Daniel Werz from the University of Freiburg
Jerome presenting at the #ICHIC-8 conference at Nankai University in Tianjin, unfortunately he had to cancel his travel and present online....
June 26, 2025 at 7:51 AM
Jerome presenting at the #ICHIC-8 conference at Nankai University in Tianjin, unfortunately he had to cancel his travel and present online....
The work of Xingyu Liu @xingyuliu9595.bsky.social in collaboration with Wei Cai in Beat Fierz @beatfierz.bsky.social group @lcbm-epfl.bsky.social and Anne-Sophie Chauvin on peptide-cyanoarenes used as photocatalysts is now accepted in @angewandtechemie.bsky.social !
doi.org/10.1002/anie...
doi.org/10.1002/anie...
June 5, 2025 at 6:57 PM
The work of Xingyu Liu @xingyuliu9595.bsky.social in collaboration with Wei Cai in Beat Fierz @beatfierz.bsky.social group @lcbm-epfl.bsky.social and Anne-Sophie Chauvin on peptide-cyanoarenes used as photocatalysts is now accepted in @angewandtechemie.bsky.social !
doi.org/10.1002/anie...
doi.org/10.1002/anie...
Have a look at BCP-EBXs, combining ethynylbenziodoxolones and bicyclo[1.1.1] pentanes (BCPs) to open new chemical space around BCP bioisosteres!
This work of Najung, Jonas and Elija has just been accepted in @angewandtechemie.bsky.social !
doi.org/10.1002/anie...
This work of Najung, Jonas and Elija has just been accepted in @angewandtechemie.bsky.social !
doi.org/10.1002/anie...
May 28, 2025 at 1:45 PM
Have a look at BCP-EBXs, combining ethynylbenziodoxolones and bicyclo[1.1.1] pentanes (BCPs) to open new chemical space around BCP bioisosteres!
This work of Najung, Jonas and Elija has just been accepted in @angewandtechemie.bsky.social !
doi.org/10.1002/anie...
This work of Najung, Jonas and Elija has just been accepted in @angewandtechemie.bsky.social !
doi.org/10.1002/anie...
Huge congratulations to Dr. Vu Trung Tin Nguyen @tinvtnguyen.bsky.social on successfully defending his PhD thesis yesterday! He's now PhD graduate number 31 from our lab!
May 28, 2025 at 8:24 AM
Huge congratulations to Dr. Vu Trung Tin Nguyen @tinvtnguyen.bsky.social on successfully defending his PhD thesis yesterday! He's now PhD graduate number 31 from our lab!
The work of Emma Robert on the diastereoselective and enantioselective addition of thiols onto cyclobutenes using bifunctional organocatalysts is now accepted in @chemicalscience.rsc.org
doi.org/10.1039/D5SC...
see also for easily accessible raw data for compounds:
doi.org/10.5281/zeno...
doi.org/10.1039/D5SC...
see also for easily accessible raw data for compounds:
doi.org/10.5281/zeno...
May 23, 2025 at 9:17 AM
The work of Emma Robert on the diastereoselective and enantioselective addition of thiols onto cyclobutenes using bifunctional organocatalysts is now accepted in @chemicalscience.rsc.org
doi.org/10.1039/D5SC...
see also for easily accessible raw data for compounds:
doi.org/10.5281/zeno...
doi.org/10.1039/D5SC...
see also for easily accessible raw data for compounds:
doi.org/10.5281/zeno...
The thirtieth PhD was also the occasion to put the group theses back in order!
April 28, 2025 at 8:58 AM
The thirtieth PhD was also the occasion to put the group theses back in order!
Pierre Palamini successfully defended his PhD thesis! He is the thirtieth PhD student to obtain their degree at LCSO. Congratulations!
April 26, 2025 at 8:44 AM
Pierre Palamini successfully defended his PhD thesis! He is the thirtieth PhD student to obtain their degree at LCSO. Congratulations!
The power of EBX reagents strikes again: enantioselective ethynylation of oxindoles developed by Yongqiang Tu and co-workers, setting the stage for the synthesis of four different alkaloids!
doi.org/10.1002/anie...
doi.org/10.1002/anie...
April 25, 2025 at 12:54 PM
The power of EBX reagents strikes again: enantioselective ethynylation of oxindoles developed by Yongqiang Tu and co-workers, setting the stage for the synthesis of four different alkaloids!
doi.org/10.1002/anie...
doi.org/10.1002/anie...
Two of our publications in most read articles in CEJ in 2023!
"Photochemical [2+2] Cycloaddition of Alkynyl Boronates"
doi.org/10.1002/chem...
"Cysteine-Cysteine Cross-Conjugation of both Peptides and Proteins with a Bifunctional Hypervalent Iodine-Electrophilic Reagent"
doi.org/10.1002/chem...
"Photochemical [2+2] Cycloaddition of Alkynyl Boronates"
doi.org/10.1002/chem...
"Cysteine-Cysteine Cross-Conjugation of both Peptides and Proteins with a Bifunctional Hypervalent Iodine-Electrophilic Reagent"
doi.org/10.1002/chem...
April 17, 2025 at 3:50 PM
Two of our publications in most read articles in CEJ in 2023!
"Photochemical [2+2] Cycloaddition of Alkynyl Boronates"
doi.org/10.1002/chem...
"Cysteine-Cysteine Cross-Conjugation of both Peptides and Proteins with a Bifunctional Hypervalent Iodine-Electrophilic Reagent"
doi.org/10.1002/chem...
"Photochemical [2+2] Cycloaddition of Alkynyl Boronates"
doi.org/10.1002/chem...
"Cysteine-Cysteine Cross-Conjugation of both Peptides and Proteins with a Bifunctional Hypervalent Iodine-Electrophilic Reagent"
doi.org/10.1002/chem...
@swisschemistry.bsky.social SCS lectureship (sponsored also by @helvchimacta.bsky.social ) of prof. @anatmilo.bsky.social from Ben Gurion University today at EPFL
April 11, 2025 at 3:27 PM
@swisschemistry.bsky.social SCS lectureship (sponsored also by @helvchimacta.bsky.social ) of prof. @anatmilo.bsky.social from Ben Gurion University today at EPFL
Spring is time to update our group photo!
April 9, 2025 at 10:19 AM
Spring is time to update our group photo!
Stefano's work on the annulation of bicyclobutanes with dienol ethers to access bicyclooctanes has been selected as one of the most popular OC publications at @chemicalscience.rsc.org in 2024! #ChemSciMostPopular
original publication:
doi.org/10.1039/D4SC...
Collection:
pubs.rsc.org/en/journals/...
original publication:
doi.org/10.1039/D4SC...
Collection:
pubs.rsc.org/en/journals/...
April 4, 2025 at 4:03 PM
Stefano's work on the annulation of bicyclobutanes with dienol ethers to access bicyclooctanes has been selected as one of the most popular OC publications at @chemicalscience.rsc.org in 2024! #ChemSciMostPopular
original publication:
doi.org/10.1039/D4SC...
Collection:
pubs.rsc.org/en/journals/...
original publication:
doi.org/10.1039/D4SC...
Collection:
pubs.rsc.org/en/journals/...
Our @snf-fns-ch.bsky.social research project "Hypervalent iodine reagents for peptide and protein modification and applications in chemical biology" has been accepted! 2 PhD and one postdoc positions are now open @lcsolab.bsky.social For more details to apply, See:
www.epfl.ch/labs/lcso/gr...
www.epfl.ch/labs/lcso/gr...
March 31, 2025 at 11:55 AM
Our @snf-fns-ch.bsky.social research project "Hypervalent iodine reagents for peptide and protein modification and applications in chemical biology" has been accepted! 2 PhD and one postdoc positions are now open @lcsolab.bsky.social For more details to apply, See:
www.epfl.ch/labs/lcso/gr...
www.epfl.ch/labs/lcso/gr...